Patents by Inventor Joseph A. Brennan
Joseph A. Brennan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180068123Abstract: A service for protecting the privacy of domain name registrants while preserving the registrant's ability to directly change the registration information or transfer the registration. A domain name registration is created that reflects the registrant's actual identity but contains contact information that is entirely associated with a privacy service.Type: ApplicationFiled: October 16, 2017Publication date: March 8, 2018Inventor: Charles Joseph Brennan, III
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Patent number: 9839648Abstract: A drug combination against acid-fast bacillus, including: an inhibitor for WecA or an ortholog thereof; and at least one of an inhibitor for MurX or an ortholog thereof and an RNA synthesis inhibitor, wherein the inhibitor for WecA or an ortholog thereof is used in combination with the at least one of an inhibitor for MurX or an ortholog thereof and an RNA synthesis inhibitor; a screening method for a drug against acid-fast bacillus; and an inhibitor for WecA or an ortholog thereof.Type: GrantFiled: June 3, 2014Date of Patent: December 12, 2017Assignees: MICROBIAL CHEMISTRY RESEARCH FOUNDATION, COLORADO STATE UNIVERSITY RESEARCH FOUNDATIONInventors: Yoshimasa Ishizaki, Masayuki Igarashi, Patrick Joseph Brennan, Dean Calvin Crick
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Patent number: 9823261Abstract: A multi-well fluid container that includes a container body is provided for use in an in vitro diagnostics automation system. The container body includes a first well having a first well size configured to hold a first fluid and an openable first well closure that covers a first well opening. The first well opening provides access to the first fluid in the first well when the openable first well closure is opened. The container body also includes a second well having a second well size configured to hold a second fluid and having an openable second well closure that covers a second well opening. The second well opening provides access to the second fluid in the second well when the openable second well closure is opened. The first well size of the first well is different than the second well size of the second well.Type: GrantFiled: October 30, 2014Date of Patent: November 21, 2017Assignee: Siemens Healthcare Diagnostics Inc.Inventors: Joseph Brennan, James Kegelman
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Patent number: 9817979Abstract: A service for protecting the privacy of domain name registrants while preserving the registrant's ability to directly change the registration information or transfer the registration. A whois record is created that reflects the registrant's actual identity but contains contact information that is entirely associated with a privacy service.Type: GrantFiled: May 25, 2012Date of Patent: November 14, 2017Assignee: Network Solutions, LLCInventor: Charles Joseph Brennan, III
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Publication number: 20170285619Abstract: Method of designing and manufacturing a distributor bar for use in a production line comprising a mixing head for providing a viscous foamable liquid mixture, a laminator with a predefined speed of at least 20 m/min, the distributor bar having a central inlet fluidly connected to a number of outlets via a main channel. The method comprises: choosing (3001) a geometry for the distributor bar and defining a set of geometrical parameters; assigning (3002) values to said parameters; creating (3003) a virtual model; simulating (3005) flow in said model by performing a Computational Fluid Dynamics simulation (CFD), taking into account (3004) a non-Newtonian shear thinning model; e) evaluating the simulated flow; building (2007) a physical distributor bar. A distributor bar, a production line, and a computer program product.Type: ApplicationFiled: August 24, 2015Publication date: October 5, 2017Inventor: Mark Joseph Brennan
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Patent number: 9522165Abstract: The present invention relates to a formulation and method for the treatment of fungal nail infections, such as those caused by Trichophyton rubrum and/or Aspergillus niger. The formulation of the invention comprises glucose oxidase, D-glucose and hydrogen peroxide in an aqueous solution. Advantageously, the formulation of the invention provides a two-stage hydrogen peroxide release for the treatment of the fungal nail infections.Type: GrantFiled: January 2, 2013Date of Patent: December 20, 2016Assignee: Institute of Technology SligoInventors: John Reginald Barrett, James Joseph Brennan, Thomas Patrick Patton
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Patent number: 9522177Abstract: The present invention relates to an antimicrobial and immunostimulatory system, applications thereof and a process for the production of the antimicrobial and immunostimulatory system. The present invention provides a storage-stable antimicrobial and immunostimulatory system comprising an oxidoreductase enzyme, a substrate for the oxidoreductase enzyme and hydrogen peroxide in an aqueous solution wherein the substrate for the oxidoreductase enzyme is present up to 90% by weight and water is present up to 20% by weight based on the weight of the total composition; the system has a pH from approximately 4 to 8; and the system provides a two-stage hydrogen peroxide release.Type: GrantFiled: December 20, 2012Date of Patent: December 20, 2016Assignee: INSTITUTE OF TECHNOLOGY SLIGOInventors: John Reginald Barrett, James Joseph Brennan, Thomas Patrick Patton
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Publication number: 20160362737Abstract: The invention provides modified nucleotide or nucleoside molecule comprising a purine or pyrimidine base and a ribose or deoxyribose sugar moiety having a removable 3?-OH blocking group covalently attached thereto, such that the 3? carbon atom has attached a group of the structure —O—Z wherein Z is any of —C(R?)2—O—R?, —C(R?)2-N(R?)2,—C(R?)2-N(H)R?, —C(R?)2-S—R? and —C(R?)2-F, wherein each R? is or is part of a removable protecting group; each R? is independently a hydrogen atom, an alkyl, substituted alkyl, arylalkyl, alkenyl, alkynyl, aryl, heteroaryl, heterocyclic, acyl, cyano, alkoxy, aryloxy, heteroaryloxy or amido group, or a detectable label attached through a linking group; or (R?)2 represents an alkylidene group of formula ?C(R??)2 wherein each R?? may be the same or different and is selected from the group comprising hydrogen and halogen atoms and alkyl groups; and wherein said molecule may be reacted to yield an intermediate in which each R? is exchanged for H or, where Z is —C(R?)2-F, the F is excType: ApplicationFiled: June 10, 2016Publication date: December 15, 2016Inventors: John MILTON, Xiaolin WU, Mark SMITH, Joseph BRENNAN, Colin BARNES, Xiaohai LIU, Silke RUEDIGER
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Patent number: 9517468Abstract: Disclosed are methods to aid in a calibration of a vertical orientation of a nozzle tip to a sample container in a processing or testing system. The method includes positioning the nozzle over a calibration target at a home height location (HM), moving the nozzle downward a distance (D) until contact with the calibration target is sensed, positioning the nozzle over the sample rack and moving the nozzle downward until contact with a registration location is sensed, imaging the sample rack and calibration target to determine a height (H) between the registration location and calibration target, and calculating a translation ratio (TR) between the height (H) measured in pixel space and the distance (D) measured in machine space. The translation ratio (TR) may be used to drive the nozzle tip to a predetermined depth. A robot calibration system is disclosed, as are other aspects.Type: GrantFiled: March 16, 2012Date of Patent: December 13, 2016Assignee: Siemens Healthcare Diagnostics Inc.Inventors: Antoine E. Haddad, John Esposito, Joseph Brennan, John Mizzer
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Publication number: 20160266155Abstract: A multi-well fluid container that includes a container body is provided for use in an in vitro diagnostics automation system. The container body includes a first well having a first well size configured to hold a first fluid and an openable first well closure that covers a first well opening. The first well opening provides access to the first fluid in the first well when the openable first well closure is opened. The container body also includes a second well having a second well size configured to hold a second fluid and having an openable second well closure that covers a second well opening. The second well opening provides access to the second fluid in the second well when the openable second well closure is opened. The first well size of the first well is different than the second well size of the second well.Type: ApplicationFiled: October 30, 2014Publication date: September 15, 2016Applicant: Siemens Healthcare Diagnostics Inc.Inventors: Joseph Brennan, James Kegelman
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Publication number: 20160266156Abstract: An anti-evaporation tube for use with an in vitro diagnostics automation system is provided. The anti-evaporation tube includes an anti-evaporation tube body configured to be automatically inserted in a container and to limit evaporation of one or more fluids in the container and an alignment portion disposed on the anti-evaporation tube body. The alignment portion is configured to automatically align the anti-evaporation tube body within the container and cause the anti-evaporation tube body to remain aligned within the container. The alignment portion includes one or more openings disposed on an upper area of the anti-evaporation tube body. The one or more openings are configured to provide ventilation.Type: ApplicationFiled: October 30, 2014Publication date: September 15, 2016Applicant: Siemens Healthcare Diagnostics Inc.Inventors: Joseph Brennan, James Kegelman, William Hudson
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Patent number: 9417255Abstract: An analyzer for use with in vitro diagnostics includes one or more containers. Each container includes a container body configured to hold one or more fluids, a closure device disposed on the container body and housing a movable cannula, and a sealing portion configured to seal off the one or more fluids in the container body from matter outside the container body when the sealing portion is closed. The system also includes one or more pick and place devices configured to move the one or more containers between different locations. The movable cannula is configured to move downward responsive to a force from the one or more pick and place devices and cause an opening in the sealing portion.Type: GrantFiled: February 19, 2014Date of Patent: August 16, 2016Assignee: Siemens Healthcare Diagnostics Inc.Inventors: Joseph Brennan, James Kegelman
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Patent number: 9393249Abstract: The present invention relates to an improved antimicrobial composition comprising a hydrogen peroxide source and one or more antimicrobial agents. Ideally, the invention relates to an antimicrobial composition comprising (i) hydrogen peroxide source and (ii) an antimicrobial agent and its associated use in therapy, particularly in the treatment of antimicrobial infections.Type: GrantFiled: March 26, 2009Date of Patent: July 19, 2016Assignee: INSTITUTE OF TECHNOLOGY SLIGOInventors: John Reginald Barrett, James Joseph Brennan, Thomas Patrick Patton
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Patent number: 9388464Abstract: The invention provides modified nucleotide or nucleoside molecule comprising a purine or pyrimidine base and a ribose or deoxyribose sugar moiety having a removable 3?-OH blocking group covalently attached thereto, such that the 3? carbon atom has attached a group of the structure —O—Z wherein Z is any of —C(R?)2-O—R?, —C(R?)2-N(R?)2, —C(R?)2-N(H)R?, —C(R?)2-S—R? and —C(R?)2-F, wherein each R? is or is part of a removable protecting group; each R? is independently a hydrogen atom, an alkyl, substituted alkyl, arylalkyl, alkenyl, alkynyl, aryl, heteroaryl, heterocyclic, acyl, cyano, alkoxy, aryloxy, heteroaryloxy or amido group, or a detectable label attached through a linking group; or (R?)2 represents an alkylidene group of formula ?C(R??)2 wherein each R?? may be the same or different and is selected from the group comprising hydrogen and halogen atoms and alkyl groups; and wherein said molecule may be reacted to yield an intermediate in which each R? is exchanged for H or, where Z is —C(R?)2-F, the F is exType: GrantFiled: August 7, 2015Date of Patent: July 12, 2016Assignee: Illumina Cambridge LimitedInventors: John Milton, Xiaolin Wu, Mark Smith, Joseph Brennan, Colin Barnes, Xiaohai Liu, Silke Ruediger
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Publication number: 20160129035Abstract: A drug combination against acid-fast bacillus, including: an inhibitor for WecA or an ortholog thereof; and at least one of an inhibitor for MurX or an ortholog thereof and an RNA synthesis inhibitor, wherein the inhibitor for WecA or an ortholog thereof is used in combination with the at least one of an inhibitor for MurX or an ortholog thereof and an RNA synthesis inhibitor; a screening method for a drug against acid-fast bacillus; and an inhibitor for WecA or an ortholog thereof.Type: ApplicationFiled: June 3, 2014Publication date: May 12, 2016Inventors: Yoshimasa ISHIZAKI, Masayuki IGARASHI, Patrick Joseph BRENNAN, Dean Calvin CRICK
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Publication number: 20160032378Abstract: The invention provides modified nucleotide or nucleoside molecule comprising a purine or pyrimidine base and a ribose or deoxyribose sugar moiety having a removable 3?-OH blocking group covalently attached thereto, such that the 3? carbon atom has attached a group of the structure —O—Z wherein Z is any of —C(R?)2-O—R?, —C(R?)2-N(R?)2, —C(R?)2-N(H)R?, —C(R?)2-S—R? and —C(R?)2-F, wherein each R? is or is part of a removable protecting group; each R? is independently a hydrogen atom, an alkyl, substituted alkyl, arylalkyl, alkenyl, alkynyl, aryl, heteroaryl, heterocyclic, acyl, cyano, alkoxy, aryloxy, heteroaryloxy or amido group, or a detectable label attached through a linking group; or (R?)2 represents an alkylidene group of formula ?C(R??)2 wherein each R?? may be the same or different and is selected from the group comprising hydrogen and halogen atoms and alkyl groups; and wherein said molecule may be reacted to yield an intermediate in which each R? is exchanged for H or, where Z is —C(R?)2-F, the F is exType: ApplicationFiled: August 7, 2015Publication date: February 4, 2016Inventors: John MILTON, Xiaolin WU, Mark SMITH, Joseph BRENNAN, Colin BARNES, Xiaohai LIU, Silke RUEDIGER
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Publication number: 20160016162Abstract: A fluid container includes a container body configured to hold one or more fluids. The container body has a first side wall and an opposing second side wall. The fluid container also includes one or more container alignment features disposed on an outer surface of the first side wall and configured to self-align the container body with a datum. The fluid container also includes one or more anti-evaporation tube alignment mechanisms disposed on one or more inner surfaces of the container body and configured to self-align an anti-evaporation tube within the container body.Type: ApplicationFiled: February 27, 2014Publication date: January 21, 2016Applicant: Siemens Healthcare Diagnostics Inc.Inventors: Joseph Brennan, James Kegelman, William Hudson, Peter Gebrian
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Publication number: 20160003861Abstract: An analyzer for use with in vitro diagnostics includes one or more containers. Each container includes a container body configured to hold one or more fluids, a closure device disposed on the container body and housing a movable cannula, and a sealing portion configured to seal off the one or more fluids in the container body from matter outside the container body when the sealing portion is closed. The system also includes one or more pick and place devices configured to move the one or more containers between different locations. The movable cannula is configured to move downward responsive to a force from the one or more pick and place devices and cause an opening in the sealing portion.Type: ApplicationFiled: February 19, 2014Publication date: January 7, 2016Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.Inventors: Joseph Brennan, James Kegelman
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Patent number: 9121060Abstract: The invention provides modified nucleotide or nucleoside molecule comprising a purine or pyrimidine base and a ribose or deoxyribose sugar moiety having a removable 3?-OH blocking group covalently attached thereto, such that the 3? carbon atom has attached a group of the structure —O—Z wherein Z is any of —C(R?)2-O—R?, —C(R?)2-N(R?)2, —C(R?)2-N(H)R?, —C(R?)2-S—R? and —C(R?)2-F, wherein each R? is or is part of a removable protecting group; each R? is independently a hydrogen atom, an alkyl, substituted alkyl, arylalkyl, alkenyl, alkynyl, aryl, heteroaryl, heterocyclic, acyl, cyano, alkoxy, aryloxy, heteroaryloxy or amido group, or a detectable label attached through a linking group; or (R?)2 represents an alkylidene group of formula ?C(R??)2 wherein each R?? may be the same or different and is selected from the group comprising hydrogen and halogen atoms and alkyl groups; and wherein said molecule may be reacted to yield an intermediate in which each R? is exchanged for H or, where Z is —C(R?)2-F, the F is exType: GrantFiled: March 8, 2013Date of Patent: September 1, 2015Assignee: Illumina Cambridge LimitedInventors: John Milton, Xiaolin Wu, Mark Smith, Joseph Brennan, Colin Barnes, Xiaohai Liu, Silke Ruediger
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Patent number: 8897810Abstract: A method for establishing wireless communication between a service vendor and a customer accepts entry of a wireless address for a customer communications device, obtained from an electronic transaction. The entry of the stored wireless address is confirmed by transmitting a first wireless message that displays a hypertext link to a network address. Response to hypertext link selection classifies the customer communications device, identifies a network applications storage location, and transmits a second wireless message to the customer device that includes a first set of programmed instructions that display a download prompt. Response to download prompt selection transmits a third wireless message to the customer communications device, including a second set of programmed instructions associated with the service vendor, wherein the second set of programmed instructions generates and displays a user-actuable link on the customer communications device.Type: GrantFiled: July 8, 2013Date of Patent: November 25, 2014Assignee: BuzzTable, Inc.Inventors: John Joseph Brennan, Warner Hardwick Siebert, Michael Christopher Cerrone, John Rider Williams