Abstract: Provided are methods, compositions and kits for depleting host nucleic acid in a biological sample, said sample having been previously obtained from an animal host.

Abstract: A targeting guide is disclosed includes a handle extending substantially along a longitudinal axis. The longitudinal handle defines one or more burr holes extending from a first side of the handle to a second side of the handle. A head is coupled to a distal end of the longitudinal handle. The head defines a plurality of guide holes sized and configured to receive a k-wire therethrough.

Abstract: Metering automation controller functionality includes accessing a project code that defines one or more operations of an industrial automation controller, analyzing the project code to identify one or more capabilities of the industrial automation controller that are utilized by the one or more operations, generating a file indicative of the one or more capabilities of the industrial automation controller, transmitting the file to a server that generates a certificate for authorizing the industrial automation controller to execute the project code, receiving the certificate from the server that identifies the file and an authorization for the industrial automation controller to execute the project code to perform the one or more operations, and transmitting the project code, the file, and the certificate to the industrial automation controller for execution.

Abstract: Metering automation controller functionality includes accessing a project code that defines one or more operations of an industrial automation controller, analyzing the project code to identify one or more capabilities of the industrial automation controller that are utilized by the one or more operations, generating a file indicative of the one or more capabilities of the industrial automation controller, transmitting the file to a server that generates a certificate for authorizing the industrial automation controller to execute the project code, receiving the certificate from the server that identifies the file and an authorization for the industrial automation controller to execute the project code to perform the one or more operations, and transmitting the project code, the file, and the certificate to the industrial automation controller for execution.

Abstract: An apparatus including a stator coil including a laminated stack including a wire-wrapped bobbin. The bobbin including a cylindrical bobbin having an inner bobbin surface and an outer bobbin surface, at least one wire wrapped around both the inner and outer surfaces of the cylindrical bobbin to form a winding, and a first layer of one or more fiber strands wound on the inner surface of the wire-wrapped cylindrical bobbin and a second layer of one or more fiber strands wound on the outer surface of the wire-wrapped cylindrical bobbin. The stator coil comprising a cured potting material potting the wire-wrapped cylindrical bobbin and bonding the wire-wrapped cylindrical bobbin together and further comprising a first layer of one or more fiber strands wound on the inner surface of the stator coil and the second layer of one or more fiber strands wound on the outer surface of the stator coil.

Abstract: A method of controlling a brake system of a vehicle. The method may include determining whether an environmental brake pad wear condition is detected that may be indicative of wear of a friction material of a brake pad assembly due to an environmental contaminant.

Abstract: A slack adjuster comprises a worm shaft that is configured to drive a worm gear adapted for coupling to a camshaft. An adjustment assembly receives slack adjustment input from a push rod and is configured to automatically rotate the worm shaft when brake slack exceeds a predetermined limit. The slack adjuster includes a manual adjuster that is moveable between a non-adjustment position where the manual adjuster is de-coupled from the worm shaft and a manual adjustment position where the manual adjuster is coupled to the worm shaft such that a position of the worm shaft can be manually adjusted as needed.

Abstract: A slack adjuster comprises a worm gear configured to be coupled to a camshaft, a worm shaft in engagement with the worm gear, and a housing having a lever configured for connection to a brake chamber output rod. The housing includes an opening that receives the worm gear and a blind bore that receives the worm shaft. An adjustment assembly is installed within the blind bore and is coupled to the worm shaft. The adjustment assembly is configured to automatically rotate the worm shaft when brake slack exceeds a predetermined limit.

Abstract: A slack adjuster comprises a worm shaft that is configured to drive a worm gear adapted for coupling to a camshaft. An adjustment assembly receives slack adjustment input from a push rod and is configured to automatically rotate the worm shaft when brake slack exceeds a predetermined limit. The slack adjuster includes a manual adjuster that is moveable between a non-adjustment position where the manual adjuster is de-coupled from the worm shaft and a manual adjustment position where the manual adjuster is coupled to the worm shaft such that a position of the worm shaft can be manually adjusted as needed.

Abstract: A brake lining wear sensor includes a thermoplastic body that is secured to a support plate between adjacent brake lining blocks. The support plate includes an opening formed within a gap between adjacent lining blocks. The thermoplastic body is received within the opening and includes a central bore that extends from a first body end to a second body end. A sensor wire is received within the bore and includes a single looped portion that extends outwardly from an end face of the second body end. The single looped portion is positioned at a predefined maximum lining wear limit. When the single looped portion is broken due to contact with a rotating brake component, a warning signal is communicated to an operator to indicate that the predefined maximum lining wear limit has been reached.

Abstract: A brake lining wear sensor includes a first portion attached to a brake lining support plate, a second portion that engages a rotating brake component after brake lining material wears to a predetermined wear level, and an internal bore that extends through the first and said second portions. A sensor wire is received within the internal bore and includes a looped portion positioned within the second portion such that the looped portion is held at a predetermined brake lining wear level limit. When the looped portion is broken due to contact with a rotating brake component, a warning signal is communicated to an operator to indicate that a wear limit has been reached.

Abstract: A brake component assembly includes a support plate and a friction lining mounted to the support plate with a plurality of fasteners. A sealing barrier is formed between the support plate and the friction lining. A liquid material is initially applied to at least one of the support plate and friction lining, which are then fastened together. The liquid material subsequently forms the sealing barrier between the support plate and the friction lining. Optionally, a flexible gasket is used to form the sealing barrier. The flexible gasket is sandwiched between the support plate and friction lining when the support plate and friction lining are fastened together.

Abstract: A brake slack adjuster is provided that includes a housing having an opening with a gear arranged within the opening. The housing includes a bore adjacent to the opening. A worm gear has an axis disposed within the bore and is an engagement with the gear. The worm gear has an end portion with helical teeth. An actuator loosely is arranged within the bore and includes an inner surface with complementary helical teeth engaging the helical teeth of the worm gear. An actuator rod includes an end arranged within the actuator aperture. The rod end is captured in the actuator by a retainer. A pawl assembly is supported by the housing and coacts with the actuator for retaining the actuator in a rotational position relative to the axis. Biasing members are arranged between the actuator and housing bore to urge the actuator engagement with the worm gear end portion.

Abstract: A brake spider includes a spider body with a central opening and a slot for receiving a camshaft and bracket assembly. The brake spider is attached to an axle housing via the central opening. The slot is defined by an inner surface that does not completely surround the camshaft. The slot allows the camshaft and bracket assembly to be removed from a wheel end assembly for service operations without having to remove other components from the wheel end assembly, such as a wheel hub, for example.

Abstract: A self-energized disk brake assembly includes gain stabilization features for controlling the multiplication of applied force against a rotatable brake member. The brake assembly includes a first brake pad supported about a first pivot and a second brake pad supported about a second pivot. An actuator applies a force to drive the brake pads into the rotatable brake member. Frictional force between the brake pads and the rotatable brake member pulls the brake pads into further engagement generating an increase in braking force from self-energization. A position of the first and second pivots is adjustable to control the amount of braking force generated from self-energization.

Abstract: A self-energized disk brake assembly includes gain stabilization features for controlling the multiplication of applied force against a rotatable brake member. The brake assembly includes a first brake pad supported about a first pivot and a second brake pad supported about a second pivot. An actuator applies a force to drive the brake pads into the rotatable brake member. Frictional force between the brake pads and the rotatable brake member pulls the brake pads into further engagement generating an increase in braking force from self-energization. A position of the first and second pivots is adjustable to control the amount of braking force generated from self-energization.

Abstract: A brake assembly has a caliper with a first brake pad and a second brake pad. The first brake pad is moveable relative to the caliper. A brake actuator moves the first brake pad and has a first threaded member and a second threaded member. The first threaded member has first thread characteristics for moving the brake actuator at a first speed and a first force. The second threaded member has a second thread characteristics for moving the brake actuator at a second speed and a second force. The first speed is greater than the second speed while the first force is lower than the second force.

Abstract: A brake assembly includes a brake pad movable on a support. The support is pivotally mounted to provide adjustment of an angle defined between the support and a centerline of a rotor. A force applied to the brake pad causes engagement between the rotor and the brake pad. A frictional force drives the brake pad along the support to increase the magnitude of braking force beyond the force applied by the actuator. The increase in braking force is proportionally controlled by adjusting the angle.

Abstract: A self-energized disk brake assembly includes gain stabilization features for controlling the multiplication of applied force against a rotatable brake member. The brake assembly includes a first brake pad supported about a first pivot and a second brake pad supported about a second pivot. An actuator applies a force to drive the brake pads into the rotatable brake member. Frictional force between the brake pads and the rotatable brake member pulls the brake pads into further engagement generating an increase in braking force from self-energization. A position of the first and second pivots is adjustable to control the amount of braking force generated from self-energization.

Abstract: A brake slack adjuster is provided that includes a housing having an opening with a gear arranged within the opening. The housing includes a bore adjacent to the opening. A worm gear has an axis disposed within the bore and is an engagement with the gear. The worm gear has an end portion with helical teeth. An actuator loosely is arranged within the bore and includes an inner surface with complementary helical teeth engaging the helical teeth of the worm gear. An actuator rod includes an end arranged within the actuator aperture. The rod end is captured in the actuator by a retainer. A pawl assembly is supported by the housing and coacts with the actuator for retaining the actuator in a rotational position relative to the axis. Biasing members are arranged between the actuator and housing bore to urge the actuator engagement with the worm gear end portion.