Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device includes an ablation system. The ablation system may include an elongate shaft having a distal region. A plurality of ablation tines may be disposed at the distal region. Each of the ablation tines may include a tubular member having a flexible circuit disposed therein. The flexible circuit may include a substrate, one or more electrodes coupled to the substrate, and a temperature sensor coupled to the substrate and positioned adjacent to the one or more electrodes. The plurality of ablation tines may include a first ablation tine and a second ablation tine. A pair of bipolar electrodes may defined by a first electrode disposed at the first ablation tine and a second electrode disposed at the second ablation tine.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device includes an ablation system. The ablation system may include an elongate shaft having a distal region. A plurality of ablation tines may be disposed at the distal region. Each of the ablation tines may include a tubular member having a flexible circuit disposed therein. The flexible circuit may include a substrate, one or more electrodes coupled to the substrate, and a temperature sensor coupled to the substrate and positioned adjacent to the one or more electrodes. The plurality of ablation tines may include a first ablation tine and a second ablation tine. A pair of bipolar electrodes may defined by a first electrode disposed at the first ablation tine and a second electrode disposed at the second ablation tine.

Abstract: A medical device that may include an elongate member having a proximal end and a distal end, and a lumen disposed through the elongate member is disclosed. The medical device may also include an opening disposed at the distal end of the elongate member in communication with the lumen, and a pushing element disposed with the lumen. The medical device may also include at least one fiducial disposed within the lumen and distal to the pushing element, and a separating mechanism disposed at the distal end of the elongate member. The separating mechanism may be configured to apply a separating force to deploy the at least one fiducial.

Abstract: A medical device that may include an elongate member having a proximal end and a distal end, and a lumen disposed through the elongate member is disclosed. The medical device may also include an opening disposed at the distal end of the elongate member in communication with the lumen, and a pushing element disposed with the lumen. The medical device may also include at least one fiducial disposed within the lumen and distal to the pushing element, and a separating mechanism disposed at the distal end of the elongate member. The separating mechanism may be configured to apply a separating force to deploy the at least one fiducial.

Abstract: A handle for a medical device includes a distal portion extending longitudinally and including a distal channel extending therethrough, the distal end of the distal portion including a connector configured to connect to a proximal end of an endoscope, a central portion slidably connected to the distal portion, the central portion extending longitudinally. The handle also includes a central channel extending therethrough, the distal end of the central portion connected to a sheath, the central portion including an introducer port extending laterally therefrom so that an auxiliary tool inserted through the introducer port is directed through a lumen of the sheath. Further, the handle includes a proximal portion slidably connected to the central portion, the proximal portion extending longitudinally and including a proximal channel extending therethrough, the distal end of the proximal portion connected to a needle so that the needle is passed through the lumen.

Abstract: A medical device may include an expandable energy delivery array reciprocally movable between a first configuration and a second configuration. The expandable energy delivery array may include a first assembly having a first proximal end piece, a first distal end piece, and one or more first energy transfer elements extending between the first proximal and first distal end pieces, and a second assembly having a second proximal end piece, a second distal end piece, and one or more second energy transfer elements extending between the second proximal and second distal end pieces. The second proximal end piece may be proximal to the first proximal end piece and the second distal end piece may be distal to the first distal end piece.

Abstract: A medical device may include an expandable energy delivery array reciprocally movable between a first configuration and a second configuration. The expandable energy delivery array may include a first assembly having a first proximal end piece, a first distal end piece, and one or more first energy transfer elements extending between the first proximal and first distal end pieces, and a second assembly having a second proximal end piece, a second distal end piece, and one or more second energy transfer elements extending between the second proximal and second distal end pieces. The second proximal end piece may be proximal to the first proximal end piece and the second distal end piece may be distal to the first distal end piece.

Abstract: A medical device that may include an elongate member having a proximal end and a distal end, and a lumen disposed through the elongate member is disclosed. The medical device may also include an opening disposed at the distal end of the elongate member in communication with the lumen, and a pushing element disposed with the lumen. The medical device may also include at least one fiducial disposed within the lumen and distal to the pushing element, and a separating mechanism disposed at the distal end of the elongate member. The separating mechanism may be configured to apply a separating force to deploy the at least one fiducial.

Abstract: A medical device that may include an elongate member having a proximal end and a distal end, and a lumen disposed through the elongate member is disclosed. The medical device may also include an opening disposed at the distal end of the elongate member in communication with the lumen, and a pushing element disposed with the lumen. The medical device may also include at least one fiducial disposed within the lumen and distal to the pushing element, and a separating mechanism disposed at the distal end of the elongate member. The separating mechanism may be configured to apply a separating force to deploy the at least one fiducial.

Abstract: An apparatus for treating tissue of a mammalian body. In one embodiment, a spring mechanism is carried by first and second tubular members and actuatable for moving a needle from a first position disposed within the distal extremity of the first tubular member to a second position extending distally of the first tubular member. In another embodiment, a nozzle is coupled to the distal extremity of an elongate tubular member for delivering a material into tissue of the mammalian body. In a further embodiment, a flexible elongate member provided with a recess is introduced into a cavity of the body to capture tissue in the recess and electrical energy is applied to such tissue in the recess so as to change the compliance of the tissue.

Abstract: This disclosure concerns systems and methods for tissue sampling using ultrasound guidance. Systems according to the various embodiments of the disclosure include a needle, for instance a biopsy needle, disposed coaxially about small gauge ultrasound probe. These systems are useful in a variety of procedures including pulmonary nodule sampling.

Abstract: A handle for a medical device includes a distal portion extending longitudinally and including a distal channel extending therethrough, the distal end of the distal portion including a connector configured to connect to a proximal end of an endoscope, a central portion slidably connected to the distal portion, the central portion extending longitudinally. The handle also includes a central channel extending therethrough, the distal end of the central portion connected to a sheath, the central portion including an introducer port extending laterally therefrom so that an auxiliary tool inserted through the introducer port is directed through a lumen of the sheath. Further, the handle includes a proximal portion slidably connected to the central portion, the proximal portion extending longitudinally and including a proximal channel extending therethrough, the distal end of the proximal portion connected to a needle so that the needle is passed through the lumen.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device includes an ablation system. The ablation system may include an elongate shaft having a distal region. A plurality of ablation tines may be disposed at the distal region. Each of the ablation tines may include a tubular member having a flexible circuit disposed therein. The flexible circuit may include a substrate, one or more electrodes coupled to the substrate, and a temperature sensor coupled to the substrate and positioned adjacent to the one or more electrodes. The plurality of ablation tines may include a first ablation tine and a second ablation tine. A pair of bipolar electrodes may defined by a first electrode disposed at the first ablation tine and a second electrode disposed at the second ablation tine.

Abstract: A medical device may include an expandable energy delivery array reciprocally movable between a first configuration and a second configuration. The expandable energy delivery array may include a first assembly having a first proximal end piece, a first distal end piece, and one or more first energy transfer elements extending between the first proximal and first distal end pieces, and a second assembly having a second proximal end piece, a second distal end piece, and one or more second energy transfer elements extending between the second proximal and second distal end pieces. The second proximal end piece may be proximal to the first proximal end piece and the second distal end piece may be distal to the first distal end piece.

Abstract: A medical device that may include an elongate member having a proximal end and a distal end, and a lumen disposed through the elongate member is disclosed. The medical device may also include an opening disposed at the distal end of the elongate member in communication with the lumen, and a pushing element disposed with the lumen. The medical device may also include at least one fiducial disposed within the lumen and distal to the pushing element, and a separating mechanism disposed at the distal end of the elongate member. The separating mechanism may be configured to apply a separating force to deploy the at least one fiducial.

Abstract: A method for treating a mammalian body having tissue comprising creating a cavity in the tissue formed by an internal surface of the tissue. The internal surface is ablated. An implant-forming material is introduced into the cavity to create an implant in the tissue. The ablation of the internal surface inhibits migration of the implant. An apparatus and kit for use with the method are provided.

Abstract: An apparatus for treating tissue of a mammalian body. In one embodiment, a spring mechanism is carried by first and second tubular members and actuatable for moving a needle from a first position disposed within the distal extremity of the first tubular member to a second position extending distally of the first tubular member. In another embodiment, a nozzle is coupled to the distal extremity of an elongate tubular member for delivering a material into tissue of the mammalian body. In a further embodiment, a flexible elongate member provided with a recess is introduced into a cavity of the body to capture tissue in the recess and electrical energy is applied to such tissue in the recess so as to change the compliance of the tissue.

Abstract: A vial adapter suitable for use in transferring fluid from a vial to a needleless syringe, the vial having a top end sealed with a septum.

Abstract: An apparatus for treating tissue of a mammalian body. In one embodiment, a spring mechanism is carried by first and second tubular members and actuatable for moving a needle from a first position disposed within the distal extremity of the first tubular member to a second position extending distally of the first tubular member. In another embodiment, a nozzle is coupled to the distal extremity of an elongate tubular member for delivering a material into tissue of the mammalian body. In a further embodiment, a flexible elongate member provided with a recess is introduced into a cavity of the body to capture tissue in the recess and electrical energy is applied to such tissue in the recess so as to change the compliance of the tissue.

Abstract: Catheter for use in biliary procedures, including a shaft having a proximal end and a distal end. A guidewire lumen is carried by the shaft extending from a location proximal the distal end of the shaft to a location proximate the distal end of the shaft. An opening is included for accessing the guidewire lumen from a location exterior the catheter shaft located distal the proximal end of the shaft. The guidewire lumen may be formed integral the catheter shaft. The catheter may be used in rapid exchange catheter procedures. The catheter may further include a port and channel design including a first opening into the guidewire lumen located proximal the distal end of the shaft, a second opening located proximal the first opening, and a channel extending longitudinally between the first opening and the second opening.