Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.

Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: Example embodiments relate to a user equipment that can receive a cellular broadcast message comprising a data element identifying the cellular broadcast message as a wireless emergency alert. The network address information (e.g., URL) can identify a network location associated with multimedia content to be transmitted to the user equipment, the multimedia content stored at a repository associated with a server device. The user equipment can, in response to detecting that the cellular broadcast message comprises the data element, send a content request to the server device associated with the network location identified by the network address information, and subsequently it can receive the multimedia content from the server device and provide the multimedia content via a graphical user interface displayed on a screen of the user equipment.

Abstract: Example embodiments relate to a user equipment that can receive a cellular broadcast message comprising a data element identifying the cellular broadcast message as a wireless emergency alert. The network address information (e.g., URL) can identify a network location associated with multimedia content to be transmitted to the user equipment, the multimedia content stored at a repository associated with a server device. The user equipment can, in response to detecting that the cellular broadcast message comprises the data element, send a content request to the server device associated with the network location identified by the network address information, and subsequently it can receive the multimedia content from the server device and provide the multimedia content via a graphical user interface displayed on a screen of the user equipment.

Abstract: Example embodiments relate to a user equipment that can receive a cellular broadcast message comprising a data element identifying the cellular broadcast message as a wireless emergency alert. The network address information (e.g., URL) can identify a network location associated with multimedia content to be transmitted to the user equipment, the multimedia content stored at a repository associated with a server device. The user equipment can, in response to detecting that the cellular broadcast message comprises the data element, send a content request to the server device associated with the network location identified by the network address information, and subsequently it can receive the multimedia content from the server device and provide the multimedia content via a graphical user interface displayed on a screen of the user equipment.

Abstract: A method for making a soil remediation product using dehydrated and decontaminated manure and a method for providing a time release of nutrients and water to turf and plants in the soil. Further, a method form making a soil remediation product using vulcanized rice hulls.

Abstract: A primary user of a payment account may designate one or more secondary users who may access and utilize the primary user's payment account. When a secondary user is making a transaction using the payment account, the primary user may be notified in real time. The transaction may be delayed for a specified period of time until approval from the primary user is received. The transaction may be processed if approval from the primary user is received within the specified period of time. On the other hand, the transaction may be canceled or denied if the primary user disapproves the transaction or if the specified period of time has expired without receiving approval from the primary user.

Abstract: One example embodiment relates to a method that comprises receiving from a first user, via a network, a listing of one or more items that are part of a garage sale. The method includes storing the item listing in a database and presenting, using at least one processor and via the network, at least part of the item listing to a second user connected to the network. The method also includes providing data to the second user indicating a geographic region or location at which the garage sale is located.

Abstract: Embodiments of the present invention relate to a method, apparatus and system for providing personal audio alert messages (PAAM) to a called party and a calling party during a call connection. In response to a call origination by the calling party, a PAAM database may be queried. One ore more personal audio alert message (PAAM) strings may be received from a database in response to the query. A first PAAM string, from the one or more PAAM strings identifying the called party to the calling party, may be returned. The call may be routed to the called party. A second PAAM string and a third PAAM string may be returned, from the one or more PAAM strings, to the called party in the routed call. The call is connected if the called party accepts the call.

Abstract: The invention concerns new oxazine derivatives of the general formula I 1