Patents by Inventor Joseph A. McDonough

Joseph A. McDonough has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240066798
    Abstract: A 3D printer includes a gantry configured to move in a plane substantially parallel to a x-y build plane and a print head configured to extrude molten material to print a 3D part in a layer-by-layer process. The 3D printer includes a platen configured to support the part being printed in the layer by layer process and positionable with a primary Z positioner along a z-axis substantially normal to the x-y build plane. The 3D printer includes a local Z positioner moved by the gantry, the local Z positioner comprising a linear motor configured to move the print head in the z-direction and having an operable range of motion extending from a nominal build position at which a nozzle of the print head is positioned in the x-y build plane to a raised position above the x-y build plane.
    Type: Application
    Filed: July 20, 2023
    Publication date: February 29, 2024
    Inventors: Paul Joseph Leavitt, Thomas Joseph McDonough, Zachary James Davis
  • Patent number: 11865111
    Abstract: Antiviral drugs targeting the N-terminal domain (NTD) of the spike receptor binding domain (RBD) and methods of treating a subject suffering from coronavirus.
    Type: Grant
    Filed: August 11, 2022
    Date of Patent: January 9, 2024
    Assignees: Southwest Research Institute, The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Government of the United States, as Represented by the Secretary of the Army
    Inventors: Jonathan A. Bohmann, Nadean M. Gutierrez, Joseph A. McDonough, Robert Francis Campbell, Michael Gordon Joyce, Rekha Panchal, Rajeshwer Sankhala, Allen Duplantier
  • Patent number: 11760015
    Abstract: A 3D printer includes a gantry configured to move in a plane substantially parallel to a x-y build plane and a print head configured to extrude molten material to print a 3D part in a layer-by-layer process. The 3D printer includes a platen configured to support the part being printed in the layer by layer process and positionable with a primary Z positioner along a z-axis substantially normal to the x-y build plane. The 3D printer includes a local Z positioner moved by the gantry, the local Z positioner comprising a linear motor configured to move the print head in the z-direction and having an operable range of motion extending from a nominal build position at which a nozzle of the print head is positioned in the x-y build plane to a raised position above the x-y build plane.
    Type: Grant
    Filed: December 30, 2021
    Date of Patent: September 19, 2023
    Assignee: Stratasys, Inc.
    Inventors: Paul Joseph Leavitt, Thomas Joseph McDonough, Zachary James Davis
  • Patent number: 11708017
    Abstract: A cup holder insert for increasing the depth of an existing cup holder includes a generally cylindrical body with an open top, a bottom and a sidewall. The body also includes an upper lip extending outwardly from the sidewall and surrounding the top. An engagement system having a flexible lip, an engagement aperture and an alignment flange functions to secure the cup holder insert into an existing cup holder to increase the existing cup holder depth. A method for inserting the cup holder insert into an existing cup holder is also disclosed.
    Type: Grant
    Filed: November 23, 2021
    Date of Patent: July 25, 2023
    Assignee: Deer Solutions LLC
    Inventors: Ronnie I Matteucci, Patrick Joseph McDonough
  • Publication number: 20230211553
    Abstract: A method of moving a print head between a plurality of partitioned chambers in a 3D printer includes providing the 3D printer having a thermal barrier having an area defined by a length and width, wherein a print head nozzle can be positioned through the thermal barrier along the width or the length and at least two partitioned chambers below the area of the thermal barrier, wherein a first chamber comprises a printing chamber and a second chamber comprises a chamber providing another functionality. The method includes raising the print head in a z direction from the second chamber to above the thermal barrier and moving the print head in a x-y direction from above the second chamber over the partition to a location above the first chamber. The method also includes lowering the print head in the z direction and into the first chamber such that an extrusion port of a nozzle of the print head is proximate a x-y print plane.
    Type: Application
    Filed: December 30, 2022
    Publication date: July 6, 2023
    Inventors: Paul Joseph Leavitt, Thomas Joseph McDonough
  • Publication number: 20230211556
    Abstract: A 3D printer includes a gantry configured to move in a plane and in a direction substantially normal to the plane and at least one print head carried by the gantry, the at least on print head comprising an extrusion nozzle at a bottom end. The 3D printer includes a plurality of partitioned chambers accessible by the at least one print head, each of the partitioned chambers having an upper edge defining an opening into each of the plurality of chambers, and a platen within a first chamber of the plurality of chambers, the platen configured to receive material from the print head to print the 3D part.
    Type: Application
    Filed: December 30, 2022
    Publication date: July 6, 2023
    Inventors: Paul Joseph Leavitt, Thomas Joseph McDonough
  • Publication number: 20230074535
    Abstract: Antiviral drugs targeting the N-terminal domain (NTD) of the spike receptor binding domain (RBD) and methods of treating a subject suffering from coronavirus.
    Type: Application
    Filed: August 11, 2022
    Publication date: March 9, 2023
    Inventors: Jonathan A. BOHMANN, Nadean M. GUTIERREZ, Joseph A. MCDONOUGH, Robert Francis CAMPBELL, Michael Gordon JOYCE, Rekha PANCHAL, Rajeshwer SANKHALA, Allen DUPLANTIER
  • Publication number: 20230065024
    Abstract: Inhibitors against SARS-COV-1, SARS-CoV-2 (Covid-19), MERS-CoV, and variants within each, including methods of treating a subject suffering from such respiratory disease.
    Type: Application
    Filed: August 12, 2022
    Publication date: March 2, 2023
    Inventors: Jonathan A. BOHMANN, Nadean M. GUTIERREZ, Joseph A. MCDONOUGH, Robert Francis CAMPBELL, Michael Gordon JOYCE, Rekha PANCHAL, Rajeshwer SANKHALA, Allen DUPLANTIER
  • Publication number: 20230028236
    Abstract: A 3D printer includes a gantry configured to move in a plane substantially parallel to a x-y build plane and a print head configured to extrude molten material to print a 3D part in a layer-by-layer process. The 3D printer includes a platen configured to support the part being printed in the layer by layer process and positionable with a primary Z positioner along a z-axis substantially normal to the x-y build plane. The 3D printer includes a local Z positioner moved by the gantry, the local Z positioner comprising a linear motor configured to move the print head in the z-direction and having an operable range of motion extending from a nominal build position at which a nozzle of the print head is positioned in the x-y build plane to a raised position above the x-y build plane.
    Type: Application
    Filed: December 30, 2021
    Publication date: January 26, 2023
    Inventors: Paul Joseph Leavitt, Thomas Joseph McDonough, Zachary James Davis
  • Publication number: 20220111780
    Abstract: A cup holder insert for increasing the depth of an existing cup holder includes a generally cylindrical body with an open top, a bottom and a sidewall. The body also includes an upper lip extending outwardly from the sidewall and surrounding the top. An engagement system having a flexible lip, an engagement aperture and an alignment flange functions to secure the cup holder insert into an existing cup holder to increase the existing cup holder depth. A method for inserting the cup holder insert into an existing cup holder is also disclosed.
    Type: Application
    Filed: November 23, 2021
    Publication date: April 14, 2022
    Applicant: Deer Solutions LLC
    Inventors: Ronnie I Matteucci, Patrick Joseph McDonough
  • Patent number: 11247599
    Abstract: A cup holder insert for increasing the depth of an existing cup holder includes a generally cylindrical body with an open top, a bottom and a sidewall. The body also includes an upper lip extending outwardly from the sidewall and surrounding the top. An engagement system having a flexible lip, an engagement aperture and an alignment flange functions to secure the cup holder insert into an existing cup holder to increase the existing cup holder depth. A method for inserting the cup holder insert into an existing cup holder is also disclosed.
    Type: Grant
    Filed: October 8, 2019
    Date of Patent: February 15, 2022
    Assignee: Deer Solutions LLC
    Inventors: Ronnie I Matteucci, Patrick Joseph McDonough
  • Publication number: 20210101514
    Abstract: A cup holder insert for increasing the depth of an existing cup holder includes a generally cylindrical body with an open top, a bottom and a sidewall. The body also includes an upper lip extending outwardly from the sidewall and surrounding the top. An engagement system having a flexible lip, an engagement aperture and an alignment flange functions to secure the cup holder insert into an existing cup holder to increase the existing cup holder depth. A method for inserting the cup holder insert into an existing cup holder is also disclosed.
    Type: Application
    Filed: October 8, 2019
    Publication date: April 8, 2021
    Applicant: Deer Solutions LLC
    Inventors: Ronnie I Matteucci, Patrick Joseph McDonough
  • Publication number: 20200345658
    Abstract: The present disclosure is directed at compositions of dimethyl trisulfide (DMTS) suitable for use for treatment of cyanide intoxication. The compositions show particularly useful stability such that the DMTS remains stable for therapeutic use at the identified time periods. The compositions are therefore particularly suitable for use in autoinjectors.
    Type: Application
    Filed: March 10, 2020
    Publication date: November 5, 2020
    Inventors: Hong DIXON, Joseph A. McDONOUGH
  • Patent number: 10576077
    Abstract: The present disclosure relates to the preparation of polymorphic mixtures of Cepharanthine.2HCl. Mixtures of at least two polymorphic forms can be formed into a mobile liquid phase in organic/aqueous solvent mixtures along with enteric polymer that can be spray dried to produce solid particulate enteric formulations for medicinal drug-treatment applications.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: March 3, 2020
    Assignee: Southwest Research Institute
    Inventors: William E. Bauta, Joseph A. McDonough, Hong Dixon, Stephen T. Wellinghoff, Kevin Fitzpatrick
  • Patent number: 10478488
    Abstract: The present invention relates to the field of pharmaceutical and vaccine formulations. More specifically, formulations which comprise an antigen comprising a mixture of oligopeptides loaded into liposome nanoparticles, optionally including an adjuvant, to provide an improved immune response.
    Type: Grant
    Filed: October 3, 2017
    Date of Patent: November 19, 2019
    Assignee: Southwest Research Institute
    Inventors: Xingguo Cheng, Kenneth H. Carson, Joseph A. McDonough, Renukaradhya J. Gourapura, Chang Won Lee, Santosh Dhakal
  • Patent number: 10350200
    Abstract: The present invention is directed at aqueous suspensions of oxime compounds, such as 2-pyridine aldoxime methyl chloride (2-PAM Cl) for autoinjectors. The suspensions are able to provide 600 mg of 2-PAM Cl in one relatively small dose of less than or equal to 1.0 mL, and are particularly useful for placement in relatively small size autoinjectors.
    Type: Grant
    Filed: January 23, 2017
    Date of Patent: July 16, 2019
    Assignee: SOUTHWEST RESEARCH INSTITUTE
    Inventors: Hong Dixon, Joseph A. McDonough, Larry A. Cabell
  • Publication number: 20190099482
    Abstract: The present invention relates to the field of pharmaceutical and vaccine formulations. More specifically, formulations which comprise an antigen comprising a mixture of oligopeptides loaded into liposome nanoparticles, optionally including an adjuvant, to provide an improved immune response.
    Type: Application
    Filed: October 3, 2017
    Publication date: April 4, 2019
    Inventors: Xingguo CHENG, Kenneth H. CARSON, Joseph A. McDONOUGH, Renukaradhya J. GOURAPURA, Chang Won LEE, Santosh DHAKAL
  • Patent number: 10117859
    Abstract: Methods for preparing suspensions of active pharmaceutical ingredients for ensuing drug delivery. The suspension may include a mixture of a relatively low dosage API and a relatively high dosage API or a mixture of an API with a suitable excipient.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: November 6, 2018
    Assignee: SOUTHWEST RESEARCH INSTITUTE
    Inventors: Hong Dixon, Larry A. Cabell, Joseph A. McDonough
  • Publication number: 20180303823
    Abstract: The present disclosure relates to the preparation of polymorphic mixtures of Cepharanthine.2HCl. Mixtures of at least two polymorphic forms can be formed into a mobile liquid phase in organic/aqueous solvent mixtures along with enteric polymer that can be spray dried to produce solid particulate enteric formulations for medicinal drug-treatment applications.
    Type: Application
    Filed: March 19, 2018
    Publication date: October 25, 2018
    Inventors: William E. BAUTA, Joseph A. McDONOUGH, Hong DIXON, Steven T. WELLINGHOFF, Kevin FITZPATRICK
  • Patent number: D927269
    Type: Grant
    Filed: October 8, 2019
    Date of Patent: August 10, 2021
    Assignee: Deer Solutions LLC
    Inventors: Ronnie I Matteucci, Patrick Joseph McDonough