Patents by Inventor Joseph A. Pike

Joseph A. Pike has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHESIS AND NOVEL SALT FORMS OF (R)-5-((E)-2-PYRROLIDIN-3-YLVINYL)PYRIMIDINE
    Publication number: 20230295126
    Abstract: The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine, its salt forms, and novel polymorphic forms of these salts.
    Type: Application
    Filed: December 2, 2022
    Publication date: September 21, 2023
    Inventors: Srinivasa Rao AKIREDDY, Balwinder Singh BHATTI, Timothy J. CUTHBERTSON, Gary Maurice Dull, Graig Harrison MILLER, Joseph Pike MITCHENER, Julio A. MUNOZ, Pieter Albert OTTEN
  • Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine
    Patent number: 11542253
    Abstract: The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine, its salt forms, and novel polymorphic forms of these salts.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: January 3, 2023
    Assignee: Oyster Point Pharma, Inc.
    Inventors: Srinivasa Rao Akireddy, Balwinder Singh Bhatti, Timothy J. Cuthbertson, Gary Maurice Dull, Craig Harrison Miller, Joseph Pike Mitchener, Jr., Julio A. Munoz, Pieter Albert Otten
  • SYNTHESIS AND NOVEL SALT FORMS OF (R)-5-((E)-2-PYRROLIDIN-3-YLVINYL)PYRIMIDINE
    Publication number: 20210371401
    Abstract: The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine, its salt forms, and novel polymorphic forms of these salts.
    Type: Application
    Filed: January 8, 2021
    Publication date: December 2, 2021
    Inventors: Srinivasa Rao AKIREDDY, Balwinder Singh BHATTI, Timothy J. CUTHBERTSON, Gary Maurice DULL, Craig Harrison MILLER, Joseph Pike MITCHENER, JR., Julio A. MUNOZ, Pieter Albert OTTEN
  • Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine
    Patent number: 10919879
    Abstract: The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine, its salt forms, and novel polymorphic forms of these salts.
    Type: Grant
    Filed: August 14, 2019
    Date of Patent: February 16, 2021
    Assignee: Oyster Point Pharma, Inc.
    Inventors: Srinivasa Rao Akireddy, Balwinder Singh Bhatti, Timothy J. Cuthbertson, Gary Maurice Dull, Craig Harrison Miller, Joseph Pike Mitchener, Jr., Julio A. Munoz, Pieter Albert Otten
  • SYNTHESIS AND NOVEL SALT FORMS OF (R)-5-((E)-2-PYRROLIDIN-3-YLVINYL)PYRIMIDINE
    Publication number: 20200207740
    Abstract: The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine, its salt forms, and novel polymorphic forms of these salts.
    Type: Application
    Filed: August 14, 2019
    Publication date: July 2, 2020
    Inventors: Srinivasa Rao AKIREDDY, Balwinder Singh BHATTI, Timothy J. CUTHBERTSON, Gary Maurice DULL, Craig Harrison MILLER, Joseph Pike MITCHENER, JR., Julio A. MUNOZ, Pieter Albert OTTEN
  • Salt forms of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine
    Patent number: 10421745
    Abstract: The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine, its salt forms, and novel polymorphic forms of these salts.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: September 24, 2019
    Assignee: Oyster Point Pharma, Inc.
    Inventors: Srinivasa Rao Akireddy, Balwinder Singh Bhatti, Timothy J. Cuthbertson, Gary Maurice Dull, Craig Harrison Miller, Joseph Pike Mitchener, Jr., Julio A. Munoz, Pieter Albert Otten
  • NOVEL SALT FORMS OF (R)-5-((E)-2-PYRROLIDIN-3-YLVINYL)PYRIMIDINE
    Publication number: 20190071428
    Abstract: The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine, its salt forms, and novel polymorphic forms of these salts.
    Type: Application
    Filed: April 25, 2018
    Publication date: March 7, 2019
    Inventors: Srinivasa Rao AKIREDDY, Balwinder Singh BHATTI, Timothy J. CUTHBERTSON, Gary Maurice DULL, Craig Harrison MILLER, Joseph Pike MITCHENER, JR., Julio A. MUNOZ, Pieter Albert OTTEN
  • Thermal insulation
    Patent number: 9993990
    Abstract: A thermal shield material includes a laminate of a homogeneously blended fiber mat of fiberglass, polyester and bi-component polyester, a plurality of tufts disposed on only one side of mat, the tufts formed by needling the mat from a single side, first and second adhesive layers disposed on first and second sides of the blended fiber mat, respectively, at least one of the adhesive layers being a heat activated adhesive and, a foil layer on the heat activate adhesive layer.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: June 12, 2018
    Assignee: CTA Acoustics, Inc.
    Inventors: Shawn Jose Guzman, Matthew Bargo, II, Demetrio Bellocido Borja, James Joseph Pike
  • Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine
    Patent number: 9981949
    Abstract: The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine, its salt forms, and novel polymorphic forms of these salts.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: May 29, 2018
    Assignee: Oyster Point Pharma, Inc.
    Inventors: Srinivasa Rao Akireddy, Balwinder Singh Bhatti, Timothy J. Cuthbertson, Gary Maurice Dull, Craig Harrison Miller, Joseph Pike Mitchener, Jr., Julio A. Munoz, Pieter Albert Otten
  • SYNTHESIS AND NOVEL SALT FORMS OF (R)-5-((E)-2-PYRROLIDIN-3-YLVINYL)PYRIMIDINE
    Publication number: 20170260167
    Abstract: The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine, its salt forms, and novel polymorphic forms of these salts.
    Type: Application
    Filed: November 17, 2016
    Publication date: September 14, 2017
    Inventors: Srinivasa Rao Akireddy, Balwinder Singh Bhatti, Timothy J. Cuthbertson, Gary Maurice Dull, Craig Harrison Miller, Joseph Pike Mitchener, JR., Julio A. Munoz, Pieter Albert Otten
  • SYNTHESIS AND NOVEL SALT FORMS OF (R)-5-((E)-2-PYRROLIDIN-3YLVINYL)PYRIMIDINE
    Publication number: 20160046609
    Abstract: The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine, its salt forms, and novel polymorphic forms of these salts.
    Type: Application
    Filed: August 21, 2015
    Publication date: February 18, 2016
    Inventors: Srinivasa Rao Akireddy, Balwinder Singh Bhatti, Timothy J. Cuthbertson, Gary Maurice Dull, Craig Harrison Miller, Joseph Pike Mitchener, Julio A. Munoz, Pieter Albert Otten
  • Thermal and acoustical insulation
    Patent number: 9193131
    Abstract: A thermal shield material comprises a laminate of a homogeneously blended fiber mat of fiberglass, polyester and bi-component polyester, a plurality of tufts disposed on only one side of the laminate mat, the tufts formed by needling the laminate mat from a single side, first and second pressure sensitive adhesive layers disposed on first and second sides of the blended fiber mat, a foil layer on at least one of the first and second pressure sensitive adhesive layers.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: November 24, 2015
    Assignee: CTA Acoustics, Inc.
    Inventors: Shawn Jose Guzman, Matthew Bargo, II, Demetrio Bellocido Borja, James Joseph Pike
  • Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3ylvinyl)pyrimidine
    Patent number: 9145396
    Abstract: The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine, its salt forms, and novel polymorphic forms of these salts.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: September 29, 2015
    Assignee: Targacept, Inc.
    Inventors: Srinivasa Rao Akireddy, Balwinder Singh Bhatti, Timothy J. Cuthbertson, Gary Maurice Dull, Craig Harrison Miller, Joseph Pike Mitchener, Julio A. Munoz, Pieter Albert Otten
  • Thermal Insulation
    Publication number: 20150266265
    Abstract: A thermal shield material includes a laminate of a homogeneously blended fiber mat of fiberglass, polyester and bi-component polyester, a plurality of tufts disposed on only one side of mat, the tufts formed by needling the mat from a single side, first and second adhesive layers disposed on first and second sides of the blended fiber mat, respectively, at least one of the adhesive layers being a heat activated adhesive and, a foil layer on the heat activate adhesive layer.
    Type: Application
    Filed: March 30, 2015
    Publication date: September 24, 2015
    Inventors: SHAWN JOSE GUZMAN, MATTHEW BARGO, II, DEMETRIO BELLOCIDO BORJA, JAMES JOSEPH PIKE
  • Salts of physiologically active and psychoactive alkaloids and amines simultaneously exhibiting bioavailability and abuse resistance
    Patent number: 8859622
    Abstract: Drug substances comprising a pharmaceutically acceptable organic acid addition salt of amine containing pharmaceutically active compounds useful for the treatment of a therapeutic ailment administration and exhibiting prophylactic properties when employed in non-therapeutic administration.
    Type: Grant
    Filed: April 3, 2008
    Date of Patent: October 14, 2014
    Assignee: Pisgah Laboratories, Inc.
    Inventors: David William Bristol, Clifford Riley King, Joseph Pike Mitchener, Jr., Vicki Haynes Audia
  • SYNTHESIS AND NOVEL SALT FORMS OF (R)-3-((E)-2-(PYRROLIDIN-3-YL)VINYL)-5-(TETRAHYDROPYRAN-4-YLOXY)PYRIDINE
    Publication number: 20140107163
    Abstract: The present invention relates to (R)-3-((E)-2-(pyrrolidin-3-yl)vinyl)-5-(tetrahydropyran-4-yloxy)pyridine, its salt forms, and to processes for the commercial-scale production of these compounds in sufficient purity and quality for use in pharmaceutical compositions.
    Type: Application
    Filed: December 16, 2013
    Publication date: April 17, 2014
    Applicant: Targecept, Inc.
    Inventors: Srinvasa Rao Akireddy, Scott R. Breining, Timothy J. Cuthbertson, Gary Maurice Dull, Gregory J. Gatto, John Genus, Phillip S. Hammond, Joseph Pike Mitchener, JR., Julio A. Munoz, Pieter Albert Otten, Daniel Yohannes, Nikolai Fedorov
  • SYNTHESIS AND NOVEL SALT FORMS OF (R)-5-((E)-2-PYRROLIDIN-3YLVINYL)PYRIMIDINE
    Publication number: 20140066460
    Abstract: The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine, its salt forms, and novel polymorphic forms of these salts.
    Type: Application
    Filed: November 7, 2013
    Publication date: March 6, 2014
    Applicant: Targacept, Inc.
    Inventors: Srinivasa Rao Akireddy, Balwinder Singh Bhatti, Timothy J. Cuthbertson, Gary Maurice Dull, Craig Harrison Miller, Joseph Pike Mitchener, Julio A. Munoz, Pieter Albert Otten
  • Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3YLVINYL)pyrimidine
    Patent number: 8604191
    Abstract: The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-yl)pyrimidine, novel salt forms, and novel polymorphic forms of these salts.
    Type: Grant
    Filed: November 30, 2009
    Date of Patent: December 10, 2013
    Assignee: Targacept, Inc.
    Inventors: Srinivasa Rao Akireddy, Balwinder Singh Bhatti, Timothy J. Cuthbertson, Gary Maurice Dull, Craig Harrison Miller, Joseph Pike Mitchener, Jr., Julio A. Munoz, Pieter Albert Otten
  • Salts of physiologically active and psychoactive alkaloids and amines simultaneously exhibiting bioavailability and abuse resistance
    Patent number: 8575151
    Abstract: Drug substances comprising a pharmaceutically acceptable organic acid addition salt of amine containing pharmaceutically active compounds useful for the treatment of a therapeutic ailment administration and exhibiting prophylactic properties when employed in non-therapeutic administration.
    Type: Grant
    Filed: April 3, 2008
    Date of Patent: November 5, 2013
    Assignee: Pisgah National Laboratories, Inc.
    Inventors: David William Bristol, Clifford Riley King, Joseph Pike Mitchener, Jr., Vicki Haynes Audia
  • Salts of physiologically active and psychoactive alkaloids and amines simultaneously exhibiting bioavailability and abuse resistance
    Patent number: 8334322
    Abstract: Drug substances comprising a pharmaceutically acceptable organic acid addition salt of amine containing pharmaceutically active compounds useful for the treatment of a therapeutic ailment administration and exhibiting prophylactic properties when employed in non-therapeutic administration.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: December 18, 2012
    Assignee: Pisgah Laboratories, LLC
    Inventors: David William Bristol, Clifford Riley King, Joseph Pike Mitchener, Jr., Vicki Haynes Audia