Abstract: There is provided a nozzle for a fan assembly. The nozzle comprises an air inlet, a first air outlet and a second air outlet that are oriented in convergent directions, and a valve for controlling the first and second air outlets. The valve comprises one or more valve members that are moveable to simultaneously adjust the size of the first air outlet and inversely adjust the size of the second air outlet. The nozzle further comprises a third air outlet and a fourth air outlet, the third air outlet being opposite the fourth air outlet, the third and fourth air outlets being oriented in convergent directions, and the third air outlet and the fourth air outlet each being substantially perpendicular to each of the first and second air outlets.

Abstract: Example implementations include a method, apparatus and computer-readable medium of configuring a license for a component configurable with a computer system, comprising storing the component on the computer system. The implementations further include encoding computer system information corresponding to the computer system into a barcode, such as a Quick Response (QR) code. Additionally, the implementations further include displaying the barcode and a license identifier field. Additionally, the implementations further include receiving a license identifier in the license identifier field, wherein the license identifier is based on the barcode. Additionally, the implementations further include decoding the license for the component based on the license identifier.

Abstract: An air conditioning appliance or a make-up air (MUA) assembly may include an intake conduit and a secondary air duct. The intake conduit may be attachable to a housing of the air conditioning appliance. The intake conduit may define an intake passage upstream from the indoor inlet. The intake conduit may further define a secondary inlet upstream from the intake passage to permit air thereto. The secondary air duct may extend from the intake conduit outside of the housing upstream from the secondary inlet to direct air thereto.

Abstract: Systems and methods for identifying a condition associated with an individual in a home environment are provided. Sensors associated with the home environment detect data, which is captured and analyzed by a local or remote processor to identify the condition. In some instances, the sensors are configured to capture data indicative of electricity use by devices associated with the home environment, including, e.g., which devices are using electricity, what date/time electricity is used by each device, how long each device uses electricity, and/or the power source for the electricity used by each device. The processor analyzes the captured data to identify any abnormalities or anomalies, and, based upon any identified abnormalities or anomalies, the processor determines a condition (e.g., a medical condition) associated with an individual in the home environment. The processor generates and transmits a notification indicating the condition associated with the individual to a caregiver of the individual.

Abstract: An apparatus for providing material feedstock into a plasma of a plasma torch includes a material feeding device having an input end and an output end. The output end of the material feeding device extends at least partially around the periphery of a plasma generated near the output end of the plasma torch. The material feeding device is oriented at an angle with respect to a central axis of the plasma torch.

Abstract: A method of facilitating first mile/last mile transfer of a vehicle includes analyzing a first route using a first trained machine learning model and a second route using a second trained machine learning model to determine, respectively, an incentive to a first user and a cost to a second user; causing a first message including the incentive to be displayed to the first user via an electronic device of the first user; and causing a second message including the cost to be displayed to the second user via an electronic device of the second user.

Abstract: Processes of making [1.1.1]propellane utilize reaction conditions that include reacting 1,1-dibromo-2,2-bis(chloromethyl)cyclopropane with an effective amount of solid magnesium.

Abstract: A method and rivet apparatus comprise a rivet block, the rivet block comprising a rivet block, a pin bore, and a rivet feed bore. The rivet block is comprised of a top end and a bottom end. The pin bore includes a top end and a bottom end and is disposed within the rivet block. The pin bore extends from the top end to the bottom end of the rivet block and guides a rivet pin that slides downward within the pin bore to push a head of a rivet into a workpiece. The rivet feed bore includes a top end and a bottom end and is disposed within the rivet block. The rivet feed bore extends from the top end to the bottom end of the rivet block, accepts the rivet at the top end of the rivet feed bore, and guides the rivet to the bottom end of the rivet feed bore. The rivet feed bore intersecting the pin bore between the top end and the bottom end of the pin bore at an oblique angle.

Abstract: This invention is in the area of improved compounds and methods for treating selected cancers and hyperproliferative disorders.

Abstract: This invention is in the area of improved compounds, compositions and methods of transiently protecting healthy cells, and in particular hematopoietic stem and progenitor cells (HSPC) as well as renal cells, from damage associated with DNA damaging chemotherapeutic agents. In one aspect, improved protection of healthy cells is disclosed using disclosed compounds that act as highly selective and short, transiently-acting cyclin-dependent kinase 4/6 (CDK 4/6) inhibitors when administered to subjects undergoing DNA damaging chemotherapeutic regimens for the treatment of proliferative disorders.

Abstract: A lower drill tool that is structurally configured to receive a bracket, and, to cooperate with an upper drill tool having a pair of spaced apart drill bits. The lower drill tool has part receiving surface, a pair of spaced apart drill bores, a central bore, a centering nub and a biasing member. The drill bores extend downwardly away from the part receiving surface. The central bore is between the drill bores and extends downwardly away from the part receiving surface. The centering nub is slidable within the central bore, and has an upper tip extendable beyond the part receiving surface, positionable between an extended position and a partially retracted position. The upper tip has a conical configuration. The biasing member is positioned within the central bore and biases the centering nub toward the extended position. A drill system and a method are also disclosed.

Abstract: This invention directed to methods for treating select RB-positive cancers and other Rb-positive abnormal cellular proliferative disorders using CDK4/6 inhibitors in specific dosing and combination or alternation regimes. In one aspect, treatments of select RB-positive cancers are disclosed using specific CDK4/6 inhibitors in combination or alternation with a Bruton's tyrosine kinase (BTK) inhibitor.

Abstract: Described herein are PARP1 inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of cancer.

Abstract: An air distribution assembly for a recreational vehicle may include a frame mounted within an opening of the recreational vehicle and a baffle positioned therein to sealing divide an air handling chamber into an air supply side and an air return side. The baffle may include mounting flanges for rigidly connecting the baffle to the inside surface of the frame.

Abstract: A single-package air conditioner unit may include, a housing, an outdoor heat exchanger assembly, an indoor heat exchanger assembly, a compressor, an electronics casing, and an electronics board. The housing may define an outdoor portion and an indoor portion. The outdoor heat exchanger assembly may be disposed in the outdoor portion and include an outdoor heat exchanger and an outdoor fan. The indoor heat exchanger assembly may be disposed in the indoor portion and include an indoor heat exchanger and an indoor fan. The compressor may be in fluid communication with the outdoor heat exchanger and the indoor heat exchanger to circulate a refrigerant between the outdoor heat exchanger and the indoor heat exchanger. The electronics casing may be disposed in the outdoor portion apart from the outdoor heat exchanger. The electronics casing may define a board chamber in which the electronics board may be mounted.

Abstract: A method and rivet apparatus to rivet a workpiece comprises an upper riveting portion and a lower riveting portion. The lower riveting portion comprising a fixed base, support member, and a pin assembly. The pin assembly comprises a center pin, a forming pin, a first biasing member, an outer shroud, and a second biasing member. The center pin pushes against a tail of a rivet to deform the tail of the rivet. The forming pin, fixedly coupled to the support member, pushes against the tail of the rivet to deform the tail of the rivet. The first biasing member, disposed below the center pin, biases the center pin through the forming pin and away from the support member. The outer shroud encircles the forming pin and the center pin. The second biasing member, disposed below the outer shroud, biases the outer shroud away from the support member.

Abstract: Described herein is a method for obtaining a selective estrogen receptor degrader, and compounds used in preparing the selective estrogen receptor degrader.

Abstract: Disclosed herein are compounds of Formula (A) as defined herein, and combinations of compounds, for treating amylodosis. Some of the types of amyloidosis that are treated include amyloid light-chain (AL) amyloidosis, amyloid type A (AA) amyloidosis, dialysis-related amyloidosis (DRA), familial or hereditary amyloidosis, age-related (senile) systemic amyloidosis, and organ-specific amyloidosis. In various embodiments, a compound of the Formula (A) is used in combination with a corticosteroid for the treatment of amyloidosis.

Abstract: A battery tray for an electric vehicle includes a tub component that has a floor portion and a perimeter wall portion that integrally extends upward around a peripheral edge of the floor portion to border a battery containment area of the tub component. The tub component may include a plurality of cross member portions that integrally interconnect with the floor portion and the perimeter wall portion so as to span laterally across the battery containment area to divide the battery containment area into separate compartments. A support structure of the battery tray may have an elongated member coupled at an exterior side of each of opposing longitudinal sections of the perimeter wall portion of the tub component.

Abstract: A method of manufacturing a thin film optical apparatus includes providing a substrate and applying an alignment layer over the substrate. The alignment layer ranges from about 50 to 100 nm in thickness. The method includes imprinting a hologram with a desired optic pattern onto the alignment layer and applying at least one layer of mesogen material over the alignment layer.