Abstract: The first objective comparison of automated and human segmentation of magnetic resonance images, or MRI, using a blinded controlled assessment study. Computers connected over a network divide duties including computerized segmenting of the images, manual segmenting of the images, comparison of the computer segmented images and the manually segmented images, and scoring of the images for accuracy. The scores are evaluated to update configuration parameters of a neural network.

Abstract: There is a need for more effective and efficient heightened need prediction. In one example, a method comprises, during an online prediction phase: receiving incoming monitoring data associated with the user profile; performing anomaly reduction on the incoming monitoring data to generate anomaly-reduced incoming monitoring data; generating an incoming monitoring window based on the anomaly-reduced incoming monitoring data; processing the incoming monitoring window using a trained heightened need prediction machine learning model to determine a heightened need prediction for the incoming monitoring window; and in response to determining that the heightened need prediction is positive, performing one or more responsive actions by communicating with one or more client devices associated with the user profile.

Abstract: Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.

Abstract: Apparatuses, systems, and methods are disclosed for a surgical device with suction capabilities to effectively remove fluid, tissue, and other debris from a surgical site and with a gripper for manipulating tissues and other anatomical structures during surgery. The surgical device also includes a handle having an actuator operable for controlling a position of the gripper and a suction control for adjusting a suctioning level of the device as desired, where the actuator and suction control are arranged on the handle to facilitate individual or simultaneous operation of both mechanisms.

Abstract: Airborne LiDAR bathymetry systems and methods of use are provided. The airborne LiDAR bathymetry system can collect topographic data and bathymetric data at high altitudes. The airborne LiDAR bathymetry system has a receiver system, a detector system, and a laser transmission system.

Abstract: A system and method for identifying over sedation risk factors and generating appropriate alerts for healthcare professionals as a result of an algorithm triggered based whether a calculated over sedation risk score/level for the patient crosses a predefined threshold, and determine whether the patient score is at a low, moderate, or high risk for over sedation. If the patient is at a moderate or high risk, an alert may be triggered and displayed to the healthcare professional, along with data associated with the alert in a synchronized timeline displayed on a user interface.

Abstract: A multilayer integral geogrid, including one or more cellular layers, has a plurality of oriented multilayer strands interconnected by partially oriented multilayer junctions with an array of openings therein. The multilayer integral geogrid having one or more cellular layers is produced from a coextruded or laminated multilayer polymer starting sheet. The integral geogrid has a multilayer construction, with at least one outer layer thereof having the cellular structure. By virtue of the cellular layer structure, the multilayer integral geogrid provides for increased layer vertical compressibility under load, resulting in enhanced material properties that provide performance benefits to use of the multilayer integral geogrid to stabilize and strengthen soil, aggregates, or other particulate materials.

Abstract: A monolayer multi-axial integral geogrid suitable for stabilizing aggregate includes a plurality of interconnected oriented strands and partially oriented junctions forming a repeating pattern of outer hexagons having an array of openings therein. Oriented ribs extending inwardly from each of said outer hexagons support and surround a smaller inner hexagon having oriented strands thus forming a plurality of trapezoidal openings and a single hexagonal opening. The oriented strands and partially oriented junctions of the outer hexagons form a plurality of linear strong axis strands that extend continuously throughout the entirety of the geogrid and form additional triangular openings. The geogrid thus includes three different repeating geometric shapes. The inner hexagons preferably also can move up and down, out of the plane of the geogrid. The multi-axial integral geogrid thus provides a geometry configured to engage with, confine and stabilize a large variety and quality of aggregates.

Abstract: There is provided methods for insect control, including controlling myiasis, in animals by affixing to the animal an elastomeric band having infused or contained within an insecticide, an insect repellant, lidocaine, or any combination thereof. The insect control may be a dual-mode control and may be in respect of existing or impending open wounds, including open wounds caused by castration, tail docking, umbilical cord ligation, or dehorning of an animal. There is also provided methods for castration, docking, umbilical cord ligation, or dehorning of an animal with concurrent insect control. Also provided are elastomeric bands for insect control and methods for preparing such elastomeric bands.

Abstract: Implementations of this disclosure provide an anomaly detection system and methods of performing anomaly detection on a time-series dataset. The anomaly detection may include utilization of a forecasting machine learning algorithm to obtain a prediction of points of the dataset and comparing the predicted value of a point in the dataset with the actual value to determine an error value associated with that point. Additionally, the anomaly detection may include determination of a sensitivity threshold that impacts whether points within the dataset associated with certain error values are flagged as anomalies. The forecasting machine learning algorithm may implement a seasonality component determination process that accounts for seasonality or patterns in the dataset. A search query statement may be automatically generated through importing the sensitivity threshold into a predetermined search query statement that implements that forecasting machine learning algorithm.

Abstract: A case can provide a mechanism for securely retaining a stylus with a host device while the stylus is not in use. Such a mechanism can maintain the alignment of the stylus with the host device for attachment, power transfer, and/or communication. The mechanism can further protect the stylus from impact or other external influences. The same mechanism can transition to a lower profile while not retaining the stylus (e.g., while the stylus is in use as an input device for the host device). Such a mechanism can selectably be placed into a configuration that substantially conceals the mechanism, such that it can temporarily appear to be a case or portion of the host device that does not necessarily have a dedicated receptacle for retaining the stylus.

Abstract: Methods are provided for making and recycling recyclable food grade plastic products from recycled, post-consumer plastic. The recyclable food grade plastic products may have wash away labels with printed text, graphics, or images that can be easily removed such that the plastic product may be recycled into FDA-approved food grade (i.e., food safe) plastic that is capable of being reused to manufacture new recyclable food grade products.

Abstract: A variable air flow air conditioning (HVAC) systems and methods are disclosed. In example embodiments, one or more variable speed fans or air-moving devices are in communication with ducts connecting one or more zones of a structure or other space to be air conditioned. Zone temperature sensors and air flow measurement are provided to obtain particular measurements relative to the zone it is serving while communicating with a central control. Optionally, a distributed control system can be provided such that zone sensors communicate with both the central control and its respective zone controller. The control system collects and processes multiple datasets to dynamically and proportionally adjust the volumetric air flows of each of the zones to satisfy any loads or heating/cooling demands while also maintaining a net volumetric air flow across a coil of the indoor heat transfer unit within a preset range.

Abstract: A method of diagnosing anomalous patterns from metrics data associated with a microservices-based application comprises aggregating a plurality of ingested spans into a plurality of streams of metric data. The method also comprises performing computations on a stream of metric data from the plurality of streams of metric data to identify an anomalous pattern. Further, the method comprises generating an alert in response to the anomalous pattern and querying a data set using metadata associated with the alert to retrieve additional information pertaining to the anomalous pattern.

Abstract: Minimally invasive methods and devices for introducing a spinal fixation element into a surgical site in a patient's spinal column are provided. In general, the method involves advancing a spinal fixation element in a first, lengthwise orientation along a pathway extending from a minimally invasive percutaneous incision to a spinal anchor site. As the spinal fixation element approaches the spinal anchor site, the fixation element can be manipulated to extend in a second orientation, which is preferably substantially transverse to the first orientation, to position the fixation element in relation to one or more spinal anchors.

Abstract: A method and system for facilitating interaction between users viewing same digital contents is provided. Further, the method may include a step of receiving one or more second digital content requests of the digital content. Further, the method may include a step of analyzing the first digital content request and the one or more second digital content requests. Further, the method may include a step of determining a simultaneous access of the digital content from the first user device and the one or more second user devices based on the analyzing. Further, the method may include a step of generating a notification for the simultaneous access of the digital content based on the determining. Further, the method may include a step of transmitting the notification to one or more of the first user device and the one or more second user devices.

Abstract: The first objective comparison of automated and human segmentation of magnetic resonance images, or MRI, using a blinded controlled assessment study. Computers connected over a network divide duties including computerized segmenting of the images, manual segmenting of the images, comparison of the computer segmented images and the manually segmented images, and scoring of the images for accuracy. The scores are evaluated to update configuration parameters of a neural network.

Abstract: Variable air flow air conditioning (HVAC) systems including a method of cooling or heating a structure having at least two zones. In example embodiments, individual air flow rates of the at least two zones are measured, and a control system adjusts the individual air flow rates to maintain an instantaneous measured net volumetric air flow rate at a preset volumetric air flow rate as if there was a single fan operating the system.

Abstract: Minimally invasive methods and devices are provided for positioning a spinal fixation element in relation to adjacent spinal anchors. In an exemplary embodiment, the device is a percutaneous access device that can be coupled to a spinal anchor, and the method includes the step of positioning a spinal fixation element through at least one sidewall opening of at least two percutaneous access devices such that the spinal fixation element extends in a lengthwise orientation that is substantially transverse to the longitudinal axis of each percutaneous access device. The spinal fixation element can then be advanced in the lengthwise orientation to seat the spinal fixation element in or adjacent to the receiver heads of at least two adjacent spinal anchors. A fastening element or other closure mechanism can then be applied to each spinal anchor to engage the spinal fixation element within the receiver heads of the adjacent anchors.

Abstract: There is a need for more effective and efficient heightened need prediction. In one example, a method comprises, during an online prediction phase: receiving incoming monitoring data associated with the user profile; performing anomaly reduction on the incoming monitoring data to generate anomaly-reduced incoming monitoring data; generating an incoming monitoring window based on the anomaly-reduced incoming monitoring data; processing the incoming monitoring window using a trained heightened need prediction machine learning model to determine a heightened need prediction for the incoming monitoring window; and in response to determining that the heightened need prediction is positive, performing one or more responsive actions by communicating with one or more client devices associated with the user profile.