Patents by Inventor Joseph A. Toce

Joseph A. Toce has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYMERIC NUCLEOSIDE PRODRUGS
    Publication number: 20100081627
    Abstract: Disclosed are polymeric compounds which are useful as prodrugs, comprising a chain of monomeric nucleosides, nucleoside analogs or abasic nucleosides, wherein at least one of the nucleosides or nucleoside analogs or a heterocyclic derivative thereof is pharmaceutically active and the nucleosides, nucleoside analogs or abasic nucleosides are linked by a phosphodiester group, a phosphorothioate group or an H—, alkyl or alkenyl phosphonate group.
    Type: Application
    Filed: October 2, 2009
    Publication date: April 1, 2010
    Applicant: RELIABLE BIOPHARMACEUTICAL, INC.
    Inventors: UmaShanker Sampath, Joseph A. Toce, Sourena Nadji
  • POLYMERIC NUCLEOSIDE PRODRUGS
    Publication number: 20070179112
    Abstract: Disclosed are polymeric compounds which are useful as prodrugs, comprising a chain of monomeric nucleosides, nucleoside analogs or abasic nucleosides, wherein at least one of the nucleosides or nucleoside analogs or a heterocyclic derivative thereof is pharmaceutically active and the nucleosides, nucleoside analogs or abasic nucleosides are linked by a phosphodiester group, a phosphorothioate group or an H—, alkyl or alkenyl phosphonate group.
    Type: Application
    Filed: January 29, 2007
    Publication date: August 2, 2007
    Applicant: Reliable Biopharmaceutical, Inc.
    Inventors: UmaShanker Sampath, Joseph Toce, Sourena Nadji
  • Polymeric nucleoside prodrugs
    Publication number: 20040132684
    Abstract: Disclosed are polymeric compounds which are useful as prodrugs, comprising a chain of monomeric nucleosides, nucleoside analogs or abasic nucleosides, wherein at least one of the nucleosides or nucleoside analogs or a heterocyclic derivative thereof is pharmaceutically active and the nucleosides, nucleoside analogs or abasic nucleosides are linked by a phosphodiester group, a phosphorothioate group or an H—, alkyl or alkenyl phosphonate group.
    Type: Application
    Filed: December 17, 2003
    Publication date: July 8, 2004
    Inventors: Umashanker Sampath, Joseph A. Toce, Sourena Nadji
  • Polymeric compounds useful as prodrugs
    Publication number: 20020013287
    Abstract: Disclosed are polymeric compounds which are useful as prodrugs, comprising a chain of monomeric nucleosides, nucleoside analogs or abasic nucleosides, wherein at least one of the nucleosides or nucleoside analogs or a heterocyclic derivative thereof is pharmaceutically active and the nucleosides, nucleoside analogs or abasic nucleosides are linked by a phosphodiester group, a phosphorothioate group or an H—, alkyl or alkenyl phosphonate group.
    Type: Application
    Filed: May 9, 2001
    Publication date: January 31, 2002
    Applicant: Reliable Biopharmaceuticals, Inc. St Louis Missouri
    Inventors: UmaShanker Sampath, Joseph A. Toce, Sourena Nadji
  • Sulfated acid amides having anticoagulant properties
    Patent number: 5714598
    Abstract: A sulfated acid amide having heparin-like properties of the formula:(R.sub.1)--NH--R--NH--(R.sub.1)where R.sub.1 is a di-, tri- or tetra-saccharide acid selected from cellobiose, cellotriose, cellotetrose, maltose, maltotriose and maltotetrose or mixtures thereof, and R is an alkylene of from 3 to 12 carbons, and is optionally substituted with one or more hydroxyls.
    Type: Grant
    Filed: October 4, 1995
    Date of Patent: February 3, 1998
    Assignee: Reliable Biopharmaceutical Corporation
    Inventor: Joseph A. Toce
  • Sulfated acid amides having anticoagulant properties
    Patent number: 5589588
    Abstract: A sulfated acid amide having heparin-like properties of the formula:(R.sub.1)--NH--R--NH--(R.sub.1)whereR.sub.1 is a di-, tri- or tetra-saccharide acid selected from cellobiose, cellotriose, cellotetrose, maltose, maltotriose and maltotetrose or mixtures thereof, andR is an alkylene of from 3 to 12 carbons, and is optionally substituted with one or more hydroxyls.
    Type: Grant
    Filed: March 30, 1993
    Date of Patent: December 31, 1996
    Assignee: Reliable Biopharmaceutical Corporation
    Inventor: Joseph A. Toce