Patents by Inventor Joseph A. Treadway
Joseph A. Treadway has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11407938Abstract: A structure may include a quantum structure and a barrier layer that may coat the quantum structure. The barrier layer may include aluminum and at least one material that is X1, X2, Si, O, or combinations thereof where X1 and X2 are monovalent positively charged elements and/or divalent positively charged elements. In addition, an agglomerate, a conversion element, and a method of producing a structure are disclosed.Type: GrantFiled: January 31, 2020Date of Patent: August 9, 2022Assignee: OSRAM Opto Semiconductors GmbHInventors: Erik Johansson, Joseph A. Treadway, Juanita N. Kurtin
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Patent number: 11152463Abstract: A semiconductor nanocrystal structure may include a core, an inner absorption shell surrounding the core, at least one emission shell surrounding the inner absorption shell, and an outer absorption shell surrounding the emission shell(s). The core may include a different material than the optional inner absorption shell and/or the outer absorption shell. The core may be less absorbent to electromagnetic radiation as compared to the optional inner absorption shell and/or the outer absorption shell. An optoelectronic device may include the semiconductor nanocrystal structure.Type: GrantFiled: March 18, 2020Date of Patent: October 19, 2021Assignee: OSRAM Opto Semiconductors GmbHInventors: Joseph A. Treadway, Benjamin Daniel Mangum, David O'Brien
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Publication number: 20210296440Abstract: A semiconductor nanocrystal structure may include a core, an inner absorption shell surrounding the core, at least one emission shell surrounding the inner absorption shell, and an outer absorption shell surrounding the emission shell(s). The core may include a different material than the optional inner absorption shell and/or the outer absorption shell. The core may be less absorbent to electromagnetic radiation as compared to the optional inner absorption shell and/or the outer absorption shell. An optoelectronic device may include the semiconductor nanocrystal structure.Type: ApplicationFiled: March 18, 2020Publication date: September 23, 2021Inventors: Joseph A. Treadway, Benjamin Daniel Mangum, David O'Brien
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Publication number: 20200255733Abstract: A method for fabricating a connected network of oxide-coated semiconductor structure, comprising: preparing a first solution comprising a nanocrystalline material and a first solvent; preparing a second solution comprising a surfactant and a second solvent; adding the first solution and a bifunctional linker to the second solution, thereby preparing a third solution; adding a catalyst, water and a silicate to the third solution; thereby preparing a connected network of oxide-coated semiconductor structure; wherein the ratio of the water to surfactant is more than 3.5. Furthermore, an oxide-coated semiconductor structure and a light source comprising an oxide-coated semiconductor structure are described herein.Type: ApplicationFiled: February 7, 2019Publication date: August 13, 2020Inventors: Weiwen Zhao, Juanita N. Kurtin, Joseph A. Treadway, Brian Theobald
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Patent number: 9174187Abstract: Provided herein are methods for making water-soluble nanoparticles comprising a core/shell nanocrystal that is coated with a surface layer comprising enough hydrophilic ligands to render the nanoparticle water soluble or water dispersable. Methods for crosslinking molecules on the surface of a nanoparticle, which methods can be used on the above water-soluble nanoparticles also are provided. Nanoparticle compositions resulting from these methods are also provided.Type: GrantFiled: August 6, 2009Date of Patent: November 3, 2015Assignee: Life Technologies CorporationInventors: Eric Tulsky, Kari Haley, Imad Naasani, John Mauro, Roman Rozhkov, Joseph A. Treadway
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Patent number: 9012204Abstract: The use of nanostructures to monitor or modulate changes in cellular membrane potentials is disclosed.Type: GrantFiled: July 20, 2011Date of Patent: April 21, 2015Assignee: Life Technologies CorporationInventors: Michael J. Ignatius, Elena Molokanova, Alexei Savtchenko, Joseph A. Bartel, Weiwen Zhao, Joseph A. Treadway
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Patent number: 8603792Abstract: Disclosed herein are conjugates comprising a biomolecule linked to a label that have biological activity and are useful in a wide variety of biological applications. For example, provided herein are polymerase-nanoparticle conjugates including a polymerase linked to a nanoparticle, wherein the conjugate has polymerase activity. Such conjugates can exhibit reduced aggregation and improved stochiometries wherein the average biomolecule:nanoparticle ratio approaches or equals 1:1. Also disclosed herein are improved methods for preparing such conjugates, and methods and systems for using such conjugates in biological applications such as nucleotide incorporation, primer extension and single molecule sequencing.Type: GrantFiled: March 26, 2010Date of Patent: December 10, 2013Assignee: Life Technologies CorporationInventors: Theo Nikiforov, Daniel Mazur, Xinzhan Peng, Tommie Lloyd Lincecum, Jr., Yuri Belosludtsev, Howard Reese, Dmitriy Gremyachinskiy, Roman Rozhkov, John M. Mauro, Joseph Beechem, Eric Tulsky, Imad Naasani, Kari Haley, Joseph A. Treadway
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Preparation of Stable, Bright Luminescent Nanoparticles Having Compositionally Engineered Properties
Publication number: 20130037762Abstract: A method is provided for preparing luminescent semiconductor nanoparticles composed of a first component X, a second component A, and a third component B, wherein X, A, and B are different, by combining B with X and A in an amount such that the molar ratio B:(A+B) is in the range of approximately 0.001 to 0.20 and the molar ratio X:(A+B) is in the range of approximately 0.5:1.0 to 2:1. The characteristics of these nanoparticles can be substantially similar to those of nanoparticles containing only X and B while maintaining many useful properties characteristic of nanoparticles containing only X and A; and can additionally exhibit emergent properties such as a peak emission energy less than that characteristic of a particle composed of XA or XB alone. This method is particularly applicable to the preparation of stable, bright nanoparticles that emit in the red to infrared regions of the electromagnetic spectrum.Type: ApplicationFiled: September 10, 2012Publication date: February 14, 2013Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Marc D. Schrier, Donald A. Zehnder, Joseph A. Treadway, Joseph A. Bartel -
Publication number: 20120034622Abstract: The use of nanostructures to monitor or modulate changes in cellular membrane potentials is disclosed.Type: ApplicationFiled: July 20, 2011Publication date: February 9, 2012Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Michael J. Ignatius, Elena Molokanova, Alexei Savtchenko, Joseph A. Bartel, Weiwen Zhao, Joseph A. Treadway
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Publication number: 20110306079Abstract: Provided herein are methods for making water-soluble nanoparticles comprising a core/shell nanocrystal that is coated with a surface layer comprising enough hydrophilic ligands to render the nanoparticle water soluble or water dispersable. Methods for crosslinking molecules on the surface of a nanoparticle, which methods can be used on the above water-soluble nanoparticles also are provided. Nanoparticle compositions resulting from these methods are also provided.Type: ApplicationFiled: August 6, 2009Publication date: December 15, 2011Inventors: Eric Tulsky, Kari Haley, Imad Naasani, John Mauro, Roman Rozhkow, Joseph A. Treadway
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Publication number: 20110226991Abstract: A population of nanoparticles is disclosed. The population is comprised of a plurality of core/shell nanocrystals, each including: a semiconductor core, an intermediate semiconductor shell layer disposed over the semiconductor core, an external semiconductor shell layer disposed over the intermediate semiconductor shell layer, and a hydrophilic organic layer in direct contact with the external semi-conductor shell layer. The population of nanoparticles has a ?on value of less than about 1.4.Type: ApplicationFiled: October 23, 2009Publication date: September 22, 2011Applicant: Life Technologies CorporationInventors: Joseph A. Treadway, Eric Tulsky
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Publication number: 20110003343Abstract: Disclosed herein are conjugates comprising a biomolecule linked to a label that have biological activity and are useful in a wide variety of biological applications. For example, provided herein are polymerase-nanoparticle conjugates including a polymerase linked to a nanoparticle, wherein the conjugate has polymerase activity. Such conjugates can exhibit reduced aggregation and improved stochiometries wherein the average biomolecule:nanoparticle ratio approaches or equals 1:1. Also disclosed herein are improved methods for preparing such conjugates, and methods and systems for using such conjugates in biological applications such as nucleotide incorporation, primer extension and single molecule sequencing.Type: ApplicationFiled: March 26, 2010Publication date: January 6, 2011Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Theo Nikiforov, Daniel Mazur, Xinzhan Peng, Tommie Lloyd Lincecum, JR., Yuri Belosludtsev, Howard Reese, Dmitriy Gremyachinskiy, Roman Rozhkov, John M. Mauro, Joseph Beechem, Eric Tulsky, Imad Naasani, Kari Haley, Joseph A. Treadway
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Publication number: 20100108530Abstract: A method is described for the manufacture of semiconductor nanoparticles. Improved yields are obtained by use of a reducing agent or oxygen reaction promoter.Type: ApplicationFiled: December 23, 2009Publication date: May 6, 2010Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Donald A. ZEHNDER, Joseph A. Treadway
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Preparation of stable, bright luminescent nanoparticles having compositionally engineered properties
Patent number: 7695642Abstract: A method is provided for preparing luminescent semiconductor nanoparticles composed of a first component X, a second component A, and a third component B, wherein X, A, and B are different, by combining B with X and A in an amount such that the molar ratio B:(A+B) is in the range of approximately 0.001 to 0.20 and the molar ratio X:(A+B) is in the range of approximately 0.5:1.0 to 2:1. The characteristics of the thus-prepared nanoparticles can be substantially similar to those of nanoparticles containing only X and B while maintaining many useful properties characteristic of nanoparticles containing only X and A. The nanoparticles so prepared can additionally exhibit emergent properties such as a peak emission energy less than that characteristic of a particle composed of XA or XB alone; this method is particularly applicable to the preparation of stable, bright nanoparticles that emit in the red to infrared regions of the electromagnetic spectrum.Type: GrantFiled: December 13, 2004Date of Patent: April 13, 2010Assignee: Life Technologies CorporationInventors: Marc D. Schrier, Donald A. Zehnder, Joseph A. Treadway, Joseph A. Bartel -
Preparation of Stable, Bright Luminescent Nanoparticles Having Compositionally Engineered Properties
Publication number: 20100059713Abstract: A method is provided for preparing luminescent semiconductor nanoparticles composed of a first component X, a second component A, and a third component B, wherein X, A, and B are different, by combining B with X and A in an amount such that the molar ratio B:(A+B) is in the range of approximately 0.001 to 0.20 and the molar ratio X:(A+B) is in the range of approximately 0.5:1.0 to 2:1. The characteristics of the thus-prepared nanoparticles can be substantially similar to those of nanoparticles containing only X and B while maintaining many useful properties characteristic of nanoparticles containing only X and A. The nanoparticles so prepared can additionally exhibit emergent properties such as a peak emission energy less than that characteristic of a particle composed of XA or XB alone; this method is particularly applicable to the preparation of stable, bright nanoparticles that emit in the red to infrared regions of the electromagnetic spectrum.Type: ApplicationFiled: June 15, 2009Publication date: March 11, 2010Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Marc Schrier, Donald A. Zehnder, Joseph A. Treadway, Joseph A. Bartel -
Patent number: 7559481Abstract: Devices, systems, methods, and compositions of matter can track and/or identify a library of elements, particularly for use with fluids, particulates, cells, and the like. Signals from one or more semiconductor nanocrystals may be combined to define spectral codes. Separation of signal wavelengths within dedicated wavelength ranges or windows facilitates differentiation of spectral codes, while calibration signals within the spectral codes can avoid ambiguity. Modeling based on prior testing can help derive libraries of acceptable codes.Type: GrantFiled: March 23, 2004Date of Patent: July 14, 2009Assignee: Life Technologies CorporationInventors: Joseph A. Treadway, Stephen A. Empedocles, Andrew R. Watson
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Patent number: 7172791Abstract: Methods for synthesizing luminescent nanoparticles and nanoparticles prepared by such methods are provided. The nanoparticles are prepared by a method in which an additive is included in the reaction mixture. The additive may be a Group 2 element, a Group 12 element, a Group 13 element, a Group 14 element, a Group 15 element, or a Group 16 element. In additions, a luminescent nanoparticle is provided that comprises a semiconductive core surrounded by an inorganic shell, an interfacial region and an additive present in the interfacial region or both the interfacial region and the shell.Type: GrantFiled: November 9, 2004Date of Patent: February 6, 2007Assignee: Invitrogen Corp.Inventors: Joseph A. Treadway, Donald A. Zehnder, Marc D. Schrier
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Patent number: 7147712Abstract: A method is described for the manufacture of semiconductor nanoparticles. Improved yields are obtained by use of a reducing agent or oxygen reaction promoter.Type: GrantFiled: October 1, 2002Date of Patent: December 12, 2006Assignee: Invitrogen CorporationInventors: Donald A. Zehnder, Joseph A. Treadway
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Patent number: 7144458Abstract: Nanocrystals are synthesized with a high degree of control over reaction conditions and hence product quality in a flow-through reactor in which the reaction conditions are maintained by on-line detection of characteristic properties of the product and by adjusting the reaction conditions accordingly. The coating of nanocrystals is achieved in an analogous manner.Type: GrantFiled: December 2, 2003Date of Patent: December 5, 2006Assignee: Invitrogen CorporationInventors: Donald A. Zehnder, Marcel P. Bruchez, Joseph A. Treadway, Jonathan P. Earhart
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Publication number: 20040247517Abstract: Nanocrystals are synthesized with a high degree of control over reaction conditions and hence product quality in a flow-through reactor in which the reaction conditions are maintained by on-line detection of characteristic properties of the product and by adjusting the reaction conditions accordingly. The coating of nanocrystals is achieved in an analogous manner.Type: ApplicationFiled: December 2, 2003Publication date: December 9, 2004Applicant: Quantum Dot Corporation, a corporation of the state of CaliforniaInventors: Donald A. Zehnder, Marcel P. Bruchez, Joseph A. Treadway, Jonathan P. Earhart