Patents by Inventor Joseph A. Ventura
Joseph A. Ventura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11246963Abstract: Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In one embodiment, the delivery composition includes a cationic delivery agent, a therapeutically effective amount of a hydrophobic active agent and a pharmaceutically acceptable aqueous carrier. In one embodiment, the cationic delivery agent includes polyethyleneimine (PEI). In an embodiment, the invention includes a drug delivery device including a substrate; and coated therapeutic agent particles disposed on the substrate, the coated therapeutic agent particles comprising a particulate hydrophobic therapeutic agent; and a vinyl amine polymer. Methods of making the delivery composition, as well as kits and methods of use are also included herein.Type: GrantFiled: May 16, 2014Date of Patent: February 15, 2022Assignee: Surmodics, Inc.Inventors: Joram Slager, Dale G. Swan, Darin DuMez, Joseph Ventura, Shannon Wadman, Joseph Schmidt McGonigle, Robert W. Hergenrother
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Patent number: 9999675Abstract: Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In one embodiment, the delivery composition includes a cationic delivery agent, a therapeutically effective amount of a hydrophobic active agent and a pharmaceutically acceptable aqueous carrier. In one embodiment, the cationic delivery agent includes polyethyleneimine (PEI). In a more specific embodiment, the cationic delivery agent includes branched PEI. Methods of making the delivery composition, as well as kits and methods of use are also disclosed.Type: GrantFiled: November 21, 2016Date of Patent: June 19, 2018Assignee: Surmodics, Inc.Inventors: Joseph Ventura, Shannon Wadman, Joram Slager, Joseph Schmidt McGonigle, Robert W. Hergenrother
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Publication number: 20170072057Abstract: Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In one embodiment, the delivery composition includes a cationic delivery agent, a therapeutically effective amount of a hydrophobic active agent and a pharmaceutically acceptable aqueous carrier. In one embodiment, the cationic delivery agent includes polyethyleneimine (PEI). In a more specific embodiment, the cationic delivery agent includes branched PEI. Methods of making the delivery composition, as well as kits and methods of use are also disclosed.Type: ApplicationFiled: November 21, 2016Publication date: March 16, 2017Inventors: Joseph Ventura, Shannon Wadman, Joram Slager, Joseph Schmidt McGonigle, Robert W. Hergenrother
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Patent number: 9555119Abstract: Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In one embodiment, the delivery composition includes a cationic delivery agent, a therapeutically effective amount of a hydrophobic active agent and a pharmaceutically acceptable aqueous carrier. In one embodiment, the cationic delivery agent includes polyethyleneimine (PEI). In a more specific embodiment, the cationic delivery agent includes branched PEI. Methods of making the delivery composition, as well as kits and methods of use are also disclosed.Type: GrantFiled: November 5, 2013Date of Patent: January 31, 2017Assignee: Surmodics, Inc.Inventors: Joseph Ventura, Shannon Wadman, Joram Slager, Joseph Schmidt McGonigle, Robert W. Hergenrother
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Publication number: 20140336571Abstract: Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In one embodiment, the delivery composition includes a cationic delivery agent, a therapeutically effective amount of a hydrophobic active agent and a pharmaceutically acceptable aqueous carrier. In one embodiment, the cationic delivery agent includes polyethyleneimine (PEI). In an embodiment, the invention includes a drug delivery device including a substrate; and coated therapeutic agent particles disposed on the substrate, the coated therapeutic agent particles comprising a particulate hydrophobic therapeutic agent; and a vinyl amine polymer. Methods of making the delivery composition, as well as kits and methods of use are also included herein.Type: ApplicationFiled: May 16, 2014Publication date: November 13, 2014Applicant: SurModics, Inc.Inventors: Joram Slager, Dale G. Swan, Darin DuMez, Joseph Ventura, Shannon Wadman, Joseph Schmidt McGonigle, Robert W. Hergenrother
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Publication number: 20140200411Abstract: Disclosed herein are activatable conductive compositions and methods of making and using activatable conductive compositions. In particular, activatable conductive monomers polymers are described and electrically conductive coatings that include activatable conductive polymers.Type: ApplicationFiled: January 10, 2014Publication date: July 17, 2014Applicant: SurModics, Inc.Inventors: Bruce M. Jelle, Aleksey V. Kurdyumov, Joseph Schmidt McGonigle, Robert W. Hergenrother, Nathan A. Lockwood, Joseph Ventura, Sean M. Stucke
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Publication number: 20140142166Abstract: Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In one embodiment, the delivery composition includes a cationic delivery agent, a therapeutically effective amount of a hydrophobic active agent and a pharmaceutically acceptable aqueous carrier. In one embodiment, the cationic delivery agent includes polyethyleneimine (PEI). In a more specific embodiment, the cationic delivery agent includes branched PEI. Methods of making the delivery composition, as well as kits and methods of use are also disclosed.Type: ApplicationFiled: November 5, 2013Publication date: May 22, 2014Applicant: SurModics, Inc.Inventors: Joseph Ventura, Shannon Wadman, Joram Slager, Joseph Schmidt McGonigle, Robert W. Hergenrother
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Publication number: 20090082843Abstract: The invention is directed to a self-expanding stent for implantation into a body lumen, such as an artery. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by a plurality of interconnecting members placed on the stent in a collinear arrangement such as to create at least one continuous spine which extends along the length of the stent. The invention is also directed to a stent delivery system for implantation of a stent in a vessel which includes an outer tubular member having a restraining sheath and an inner tubular member having a distal end which has a compressed stent mounted thereto. The proximal end of the inner tubular member is connected to a housing assembly which prevents the inner tubular member from moving when the outer tubular member is retracted to deploy the stent.Type: ApplicationFiled: September 25, 2008Publication date: March 26, 2009Applicant: ADVANCED CARDIOVASCULAR SYSTEMS, INC.Inventors: Daniel L. Cox, Matthew J. Fitz, William James Harrison, Michael D. Schultz, Joseph A. Ventura
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Patent number: 7491224Abstract: The invention is directed to a self-expanding stent for implantation into a body lumen, such as an artery. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by a plurality of interconnecting members placed on the stent in a collinear arrangement such as to create at least one continuous spine which extends along the length of the stent. The invention is also directed to a stent delivery system for implantation of a stent in a vessel which includes an outer tubular member having a restraining sheath and an inner tubular member having a distal end which has a compressed stent mounted thereto. The proximal end of the inner tubular member is connected to a housing assembly which prevents the inner tubular member from moving when the outer tubular member is retracted to deploy the stent.Type: GrantFiled: December 29, 2003Date of Patent: February 17, 2009Assignee: Advanced Cardiovascular Systems, Inc.Inventors: Daniel L. Cox, Matthew J. Fitz, William James Harrison, Michael D. Schultz, Joseph A. Ventura
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Publication number: 20070256255Abstract: A process for making a colored article of manufacture is disclosed. Accordingly an article of manufacture is first prepared of a material selected from the group consisting of metal, wood, glass, ceramic, masonry and polymeric materials. A polymeric coating (superstrate) is then applied to at least a portion of the surface of the article. At least a portion of the superstrate is brought into contact with a material system that contains (i) water, (ii) a carrier, (iii) a dye and (iv) a diol, under conditions calculated to bring about diffusion of said dye into said superstrate.Type: ApplicationFiled: May 4, 2006Publication date: November 8, 2007Inventors: Mark Witman, Robert Pyles, Rick Archey, Joseph Ventura
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Publication number: 20070063808Abstract: A monitoring module for a fusible switch disconnect device includes an open fuse detecting element and wire leads for completing an electrical connection with a fuse.Type: ApplicationFiled: November 22, 2006Publication date: March 22, 2007Inventors: Matthew Darr, Joseph Ventura
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Patent number: 6893458Abstract: A self-expanding stent for implantation into a body lumen, such as an artery, includes a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by a plurality of interconnecting members placed on the stent in a collinear arrangement to create at least one continuous spine which extends along the length of the stent. The cylindrical elements are nested when placed in a collapsed position. The cylindrical elements may include a W-shared portion to which the interconnecting members attach.Type: GrantFiled: June 17, 2003Date of Patent: May 17, 2005Assignee: Advanced Cardiovascular Systems, Inc.Inventors: Daniel L. Cox, Matthew J. Fitz, William James Harrison, Michael D. Schultz, Joseph A. Ventura
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Publication number: 20040158315Abstract: The invention is directed to a self-expanding stent for implantation into a body lumen, such as an artery. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by a plurality of interconnecting members placed on the stent in a collinear arrangement such as to create at least one continuous spine which extends along the length of the stent. The invention is also directed to a stent delivery system for implantation of a stent in a vessel which includes an outer tubular member having a restraining sheath and an inner tubular member having a distal end which has a compressed stent mounted thereto. The proximal end of the inner tubular member is connected to a housing assembly which prevents the inner tubular member from moving when the outer tubular member is retracted to deploy the stent.Type: ApplicationFiled: December 29, 2003Publication date: August 12, 2004Inventors: Daniel L. Cox, Matthew J. Fitz, William James Harrison, Michael D. Schultz, Joseph A. Ventura
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Publication number: 20040044399Abstract: A longitudinally flexible stent having high visibility under fluoroscopy for implanting in a body lumen. The stent includes a plurality of radiopaque interconnecting elements, configured to be expandable and encapsulated by polymeric material in a coil-like configuration, that are connected to a plurality of cylindrical elements at least at distal and proximal ends of the stent such that the radiopaque interconnecting elements are visible under fluoroscopy to enable identification of the position, diameter, and length of the stent at the implantation site. Alternatively, the stent includes a plurality of radiopaque interconnecting elements having a polymeric material filled with a radiopaque material attached to the cylindrical elements of the stent at least at the distal and proximal ends of the stent.Type: ApplicationFiled: September 4, 2002Publication date: March 4, 2004Inventor: Joseph A. Ventura
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Patent number: 6695862Abstract: The invention is directed to a self-expanding stent for implantation into a body lumen, such as an artery. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by a plurality of interconnecting members placed on the stent in a collinear arrangement such as to create at least one continuous spine which extends along the length of the stent. The invention is also directed to a stent delivery system for implantation of a stent in a vessel which includes an outer tubular member having a restraining sheath and an inner tubular member having a distal end which has a compressed stent mounted thereto. The proximal end of the inner tubular member is connected to a housing assembly which prevents the inner tubular member from moving when the outer tubular member is retracted to deploy the stent.Type: GrantFiled: July 31, 2001Date of Patent: February 24, 2004Assignee: Advanced Cardiovascular Systems, Inc.Inventors: Daniel L. Cox, Matthew J. Fitz, William James Harrison, Michael D. Schultz, Joseph A. Ventura
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Publication number: 20030212451Abstract: The invention is directed to a self-expanding stent for implantation into a body lumen, such as an artery. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by a plurality of interconnecting members placed on the stent in a collinear arrangement such as to create at least one continuous spine which extends along the length of the stent. The invention is also directed to a stent delivery system for implantation of a stent in a vessel which includes an outer tubular member having a restraining sheath and an inner tubular member having a distal end which has a compressed stent mounted thereto. The proximal end of the inner tubular member is connected to a housing assembly which prevents the inner tubular member from moving when the outer tubular member is retracted to deploy the stent.Type: ApplicationFiled: June 17, 2003Publication date: November 13, 2003Inventors: Daniel L. Cox, Matthew J. Fitz, William James Harrison, Michael D. Schultz, Joseph A. Ventura
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Patent number: 6638290Abstract: A connector assembly for connecting a surgical saw blade to a housing of a surgical instrument. The connector assembly allows a surgeon to align, insert and lock the surgical blade in the collect of the surgical instrument without any special tools, and further provides a stable and robust platform for mounting the surgical saw blade thereto. The connector assembly includes a gripper having a centrally located bore and a pair of opposing shelves. A shaft having shoulders is slidably fitted within the bore of the gripper. The shoulders communicate with ledges of the shelves to prohibit movement of the finger gripper. This same mechanism also prevents movement of a surgical saw blade, once inserted within the slot of the shaft, from becoming dislodged or ejected from the connector assembly. A biasing spring biases the gripper in a first position, but the gripper can move between the first position and a second position.Type: GrantFiled: December 6, 2000Date of Patent: October 28, 2003Assignee: Microaire Surgical Instruments, Inc.Inventors: John Pascaloff, Joseph Ventura
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Publication number: 20020068952Abstract: A connector assembly for connecting a surgical saw blade to a housing of a surgical instrument. The connector assembly allows a surgeon to align, insert and lock the surgical blade in the collet of the surgical instrument without any special tools, and further provides a stable and robust platform for mounting the surgical saw blade thereto. The connector assembly includes a gripper having a centrally located bore and a pair of opposing shelves. A shaft having shoulders is slidably fitted within the bore of the gripper. The shoulders communicate with ledges of the shelves to prohibit movement of the finger gripper. This same mechanism also prevents movement of a surgical saw blade, once inserted within the slot of the shaft, from becoming dislodged or ejected from the connector assembly. A biasing spring biases the gripper in a first position, but the gripper can move between the first position and a second position.Type: ApplicationFiled: December 6, 2000Publication date: June 6, 2002Inventors: John Pascaloff, Joseph Ventura
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Publication number: 20020052642Abstract: The invention is directed to a self-expanding stent for implantation into a body lumen, such as an artery. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by a plurality of interconnecting members placed on the stent in a collinear arrangement such as to create at least one continuous spine which extends along the length of the stent. The invention is also directed to a stent delivery system for implantation of a stent in a vessel which includes an outer tubular member having a restraining sheath and an inner tubular member having a distal end which has a compressed stent mounted thereto. The proximal end of the inner tubular member is connected to a housing assembly which prevents the inner tubular member from moving when the outer tubular member is retracted to deploy the stent.Type: ApplicationFiled: July 31, 2001Publication date: May 2, 2002Inventors: Daniel L. Cox, Matthew J. Fitz, William James Harrison, Michael D. Schultz, Joseph A. Ventura
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Patent number: 6302406Abstract: A connector assembly for connecting a surgical saw blade to a housing of a surgical instrument. The connector assembly allows a surgeon to align, insert and lock the surgical blade in the collet of the surgical instrument without any special tools, and further provides a stable and robust platform for mounting the surgical saw blade thereto. The connector assembly includes a tapered conical shaped sleeve which is positioned within the housing and rotatable in both a clockwise and counter-clock wise direction. A pair of grippers are mounted within the connector assembly and engage the surgical saw blade when the tapered conical shaped gripper sleeve is rotated in a first position. A sternum guard is also mounted to the housing.Type: GrantFiled: January 10, 2000Date of Patent: October 16, 2001Assignee: Microaire Surgical Instruments, Inc.Inventor: Joseph Ventura