Abstract: A switchable magnetic device comprising a first ferromagnetic material or layer comprising or consisting of a first rare earth nitride alloy, the first rare earth nitride alloy including at least two lanthanide species; a second ferromagnetic material or layer comprising or consisting of a second rare earth nitride alloy, the second rare earth nitride alloy including at least two lanthanide species; a blocking material or layer located between the first and second ferromagnetic materials or layers.

Abstract: The present disclosure relates generally to the field of medical devices for treating heart disease. In particular, the present disclosure relates to medical devices, systems, and methods for delivering artificial chordae tendineae in a patient. A system for delivering a chordae tendineae into a heart may include a delivery catheter. A clamp catheter may be configured to translate through the delivery catheter. A spreader may be disposed on the clamp catheter. A first clamp may be at least partially contained in the spreader in a closed configuration and may be attached to the chordae tendineae. An anchor catheter may be configured to translate through the delivery catheter and may have an anchor attached to the chordae tendineae. A sheath may be extended over the anchor catheter and anchor and may be configured to restrain an arm of the anchor.

Abstract: The disclosure is directed to improved methods for preparing substituted quinolinylcyclohexylpropanamide compounds.

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

Abstract: This disclosure teaches determining a recommended LAA closure device size based on simulations of deployment of multiple closure devices with the LAA anatomy. Input images of the patient's LAA anatomy are received. Multiple simulations are run providing options of device interaction, closure, and anchoring for multiple anchoring sites and device sizes. Gaps between the simulated deployed devices are analyzed based on leak paths and a recommended closure device size determined based on the simulated gaps.

Abstract: The present disclosure relates generally to the field of medical devices for treating heart disease. In particular, the present disclosure relates to medical devices, systems, and methods for delivering artificial chordae tendineae in a patient. A system for delivering a chordae tendineae into a heart may include a delivery catheter. A clamp catheter may be configured to translate through the delivery catheter. A spreader may be disposed on the clamp catheter. A first clamp may be at least partially contained in the spreader in a closed configuration and may be attached to the chordae tendineae. An anchor catheter may be configured to translate through the delivery catheter and may have an anchor attached to the chordae tendineae. A sheath may be extended over the anchor catheter and anchor and may be configured to restrain an arm of the anchor.

Abstract: An implantable medical device includes an expandable frame moveable between a collapsed configuration for delivery, an expanded configuration for deployment, and a distended configuration. The expandable frame includes a first frame apex and a second frame apex, a distance between the first frame apex and the second frame apex while within the expanded configuration defining an expanded configuration apex distance, a distance between the first frame apex and the second frame apex while in the distended configuration defining a distended configuration apex distance. A support member extends between the first frame apex and the second frame apex, the support member including a first end secured to the first frame apex and a second end releasably securable relative to the second frame apex, the adjustable support adapted to limit the distended configuration apex distance relative to the expanded configuration apex distance.

Abstract: A trailer adapted to haul one or more reels for carrying conveyor belts is disclosed. The trailer includes a loading means to lift the reel on the deck of the trailer. The loading means includes two articulated arms located each side of the trailer, each articulated arm comprising a first elongate member and a second elongate member pivotally mounted to the first elongate member. The first elongate members are movable relative to the trailer between a retracted position and a rearwardly extended position. The second elongate members are pivotable between a horizontal position and an upright position wherein the second elongate members are orthogonal to the first elongate members. A hoist is disposed between the second elongate members and is operable to lift the reel from the support surface to an effective height greater than an effective height of the deck. Jacks are also provided to stabilise the loading means.

Abstract: A manual vibrato control device, system and processing arrangement are disclosed. A manual vibrato includes a rotatable shaft, a raised cam section on the shaft, first and second biased collars received on the shaft either side of the cam section, the bias of the first collar being rotationally opposite to the bias of the second collar such that as the shaft rotates in one direction, it receives a return force from the first collar but does not rotate the second collar, and vice versa. Also disclosed are processing techniques to take the rotational data from rotational sensors, preferably Hall Effect, on the shaft and generate pitch change instructions for a pitch modification device. The mapping is user controllable to produce desired effects and performance.

Abstract: A clip and a clip deployment and delivery system. The clip may be engaged with a clip spreader such that simple relative movement, such as sliding movement, between the clip and clip spreader causes the clip and clip spreader to disengage from each other. A clip spreader actuator may be coupled to one arm of the clip spreader, extend distally around a distal end of the clip spreader, proximally along the other clip spreader arm, and to a proximal end at which the actuator may be controlled to open or close the clip spreader. The clips may be leaflet clips having teeth on one arm thereof and bumps on another arm thereof. The arms of the leaflet clip may be biased into a closed configuration by a flex zone which has an expanded portion extending laterally away from only one of the clip arms.

Abstract: A tissue anchor and an anchor delivery and deployment system. The tissue anchor is shiftable between a delivery configuration when housed in anchor garage of the anchor delivery and deployment system, and a deployment configuration when deployed outside the anchor garage. The anchor has a plurality of talons which may be formed from a laser cut tube. The talons may taper, such as widthwise.

Abstract: A 3D printer successively fuses sheet material in a stack to form a three-dimensional object. The sheet material may provide a mesh separating islands of material that will be fused to produce the desired three-dimensional object. The mesh provides support for the island material during the fusing process and may be removed afterwards.

Abstract: High-throughput printing, possible with multiple electron beams, is facilitated by a continuous powder bed preparation process operating in parallel to apply and pre-sinter the powder along a continuous helical path. The sintered powder may be self-supporting to allow unconstrained expansion in the radial direction when high energy is used for powder fusion.

Abstract: Methods and systems for automating carbon footprinting are disclosed. In some embodiments, the methods include a plurality of steps. In some embodiments, related to predetermined resources associated with an item from predetermined data sources is obtained. Then, estimated emission factors are calculated for each of the resources. Next, a contributory uncertainty of the data and of the emission factors is determined. Then, a user is guided based on a comparison of the respective contributory uncertainty of data related to the resources or emission factors. Next, both data related to the resources and the estimated emission factors of the resources are utilized to determine a carbon footprint of the item.

Abstract: An exercise apparatus with an adjustable rotating element around which a force transferring material wraps either clockwise or counterclockwise to provide bidirectional rotational resistance for exercising. The force transferring material is preferably guided to remain in close proximity to the rotating element while wrapping around the rotating element. Multiple attachments provide great flexibility in performing exercise or physical therapy.

Abstract: Methods and systems for automating carbon footprinting are disclosed. In some embodiments, the methods include a plurality of steps. In some embodiments, related to predetermined resources associated with an item from predetermined data sources is obtained. Then, estimated emission factors are calculated for each of the resources. Next, a contributory uncertainty of the data and of the emission factors is determined. Then, a user is guided based on a comparison of the respective contributory uncertainty of data related to the resources or emission factors. Next, both data related to the resources and the estimated emission factors of the resources are utilized to determine a carbon footprint of the item.

Abstract: A manual vibrato control device, system and processing arrangement are disclosed. A manual vibrato includes a rotatable shaft, a raised cam section on the shaft, first and second biased collars received on the shaft either side of the cam section, the bias of the first collar being rotationally opposite to the bias of the second collar such that as the shaft rotates in one direction, it receives a return force from the first collar but does not rotate the second collar, and vice versa. Also disclosed are processing techniques to take the rotational data from rotational sensors, preferably Hall Effect, on the shaft and generate pitch change instructions for a pitch modification device. The mapping is user controllable to produce desired effects and performance.

Abstract: A manual vibrato control device, system and processing arrangement are disclosed. A manual vibrato includes a rotatable shaft, a raised cam section on the shaft, first and second biased collars received on the shaft either side of the cam section, the bias of the first collar being rotationally opposite to the bias of the second collar such that as the shaft rotates in one direction, it receives a return force from the first collar but does not rotate the second collar, and vice versa. Also disclosed are processing techniques to take the rotational data from rotational sensors, preferably Hall Effect, on the shaft and generate pitch change instructions for a pitch modification device. The mapping is user controllable to produce desired effects and performance.

Abstract: The present disclosure relates generally to the field of medical devices for treating heart disease. In particular, the present disclosure relates to medical devices, systems, and methods for delivering artificial chordae tendineae in a patient. A system for delivering a chordae tendineae into a heart may include a delivery catheter. A clamp catheter may be configured to translate through the delivery catheter. A spreader may be disposed on the clamp catheter. A first clamp may be at least partially contained in the spreader in a closed configuration and may be attached to the chordae tendineae. An anchor catheter may be configured to translate through the delivery catheter and may have an anchor attached to the chordae tendineae. A sheath may be extended over the anchor catheter and anchor and may be configured to restrain an arm of the anchor.