Patents by Inventor Joseph B. Ciolino

Joseph B. Ciolino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions for the Treatment of Dry Eye and Methods of Use Thereof
    Publication number: 20230226006
    Abstract: The disclosure relates to compositions containing allyl isothiocyanate and methods of use thereof for stimulating tearing in a subject to treat dry eye.
    Type: Application
    Filed: December 15, 2022
    Publication date: July 20, 2023
    Inventor: Joseph B. Ciolino
  • Compositions for the treatment of dry eye and methods of use thereof
    Patent number: 11554104
    Abstract: The disclosure relates to compositions containing allyl isothiocyanate and methods of use thereof for stimulating tearing in a subject to treat dry eye.
    Type: Grant
    Filed: August 20, 2018
    Date of Patent: January 17, 2023
    Assignee: The Schepens Eye Research Institute, Inc.
    Inventor: Joseph B. Ciolino
  • Methods for cross-linking corneal collagen with verteporfin for the treatment of disorders of the eye
    Patent number: 10918719
    Abstract: Described are compositions and methods of using verteporfin-based photodynamic therapy (PDT) to increase the biomechanical strength of the cornea. More particularly, described herein are compositions and methods for cross-linking collagen in corneal tissue which are useful in the treatment of corneal ectatic disorders.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: February 16, 2021
    Assignee: Massachusetts Eye and Ear Infirmary
    Inventors: Saleh Alageel, Joseph B. Ciolino
  • COMPOSITIONS FOR THE TREATMENT OF DRY EYE AND METHODS OF USE THEREOF
    Publication number: 20200246301
    Abstract: The disclosure relates to compositions containing allyl isothiocyanate and methods of use thereof for stimulating tearing in a subject to treat dry eye.
    Type: Application
    Filed: August 20, 2018
    Publication date: August 6, 2020
    Inventor: Joseph B. Ciolino
  • METHODS FOR CROSS-LINKING CORNEAL COLLAGEN WITH VERTEPORFIN FOR THE TREATMENT OF DISORDERS OF THE EYE
    Publication number: 20170043015
    Abstract: Described are compositions and methods of using verteporfin-based photodynamic therapy (PDT) to increase the biomechanical strength of the cornea. More particularly, described herein are compositions and methods for cross-linking collagen in corneal tissue which are useful in the treatment of corneal ectatic disorders.
    Type: Application
    Filed: February 26, 2015
    Publication date: February 16, 2017
    Inventors: Saleh ALAGEEL, Joseph B. CIOLINO
  • Contact lens drug delivery device
    Patent number: 8414912
    Abstract: The present invention relates generally to devices and methods for administering one or more active agents to the eye of a human or animal patient in need thereof, and more particularly to devices for application to the cornea which release active agent to the eye in a controlled manner.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: April 9, 2013
    Assignees: Massachusetts Institute of Technology, Children's Medical Center Corporation, Massachusetts Eye and Ear Infirmary
    Inventors: Joseph B. Ciolino, Todd R. Hoare, Daniel S. Kohane
  • CONTACT LENS DRUG DELIVERY DEVICE
    Publication number: 20100239637
    Abstract: The present invention relates generally to devices and methods for administering one or more active agents to the eye of a human or animal patient in need thereof, and more particularly to devices for application to the cornea which release active agent to the eye in a controlled manner.
    Type: Application
    Filed: December 11, 2009
    Publication date: September 23, 2010
    Applicants: Massachusetts Institute of Technology, Children's Medical Center Corporation, Massachusetts Eye and Ear Infirmary
    Inventors: Joseph B. Ciolino, Todd R. Hoare, Daniel S. Kohane