Abstract: Light detection devices and related methods are provided. The devices may comprise a reaction structure for containing a reaction solution with a relatively high or low pH and a plurality of reaction sites that generate light emissions. The devices may comprise a device base comprising a plurality of light sensors, device circuitry coupled to the light sensors, and a plurality of light guides that block excitation light but permit the light emissions to pass to a light sensor. The device base may also include a shield layer extending about each light guide between each light guide and the device circuitry, and a protection layer that is chemically inert with respect to the reaction solution extending about each light guide between each light guide and the shield layer. The protection layer prevents reaction solution that passes through the reaction structure and the light guide from interacting with the device circuitry.

Abstract: Disclosed is a system for providing personalized self-medication, onboarding, training and improving medication adherence. The system includes a patient computer system comprising at least one processor and at least one memory component: a display, an optional input device, and an optional pointing device, a server connected to the patient computer system by a network link, the server comprising at least one processor and at least one computer readable medium wherein at least one computer readable medium comprises instructions that when executed by at least one processor, cause at least one processor to perform acts comprising: (i) responsive to patient input data, producing a patient personalized assessment; (ii) formulating a customized intervention for the patient based on the patient input data and/or personalized assessment; and (iii) presenting the patient personalized assessment and/or customized intervention on the display.

Abstract: Cryogenic analysis systems are provided that can include: a cryogenic fluid source component; an analysis component; and a thermal connection assembly operably engaged with both the cryogenic fluid source component and the analysis component to provide disengagement or engagement of the cryogenic fluid source component to/from the analysis component while maintaining the cooling status of the cryogenic fluid source component. Methods for performing sample analysis under cryogenic conditions are provided, the methods comprising: providing an analysis component; providing a cryogenic fluid source component having cryogenic fluid in a cold state; operably engaging the analysis component and the cryogenic fluid source component; preparing a sample for analysis within the analysis component; and while maintaining the cryogenic fluid in the cold state, disengaging the cryogenic fluid source component from the analysis component.

Abstract: Cryocooler assemblies are provided that can include: a first mass operatively engaged with a pumphouse configured to generate mechanical responses; a second mass operably engaged with the first mass; and an assembly between the first and second mass, the assembly configured to allow movement of the first mass in relation to the second mass. Assemblies can include a coldhead operatively engaged with a chamber configured to retain cryofluid; and a first thermally conductive mass thermally engaged with the cryofluid. Methods can include: generating a mechanical response about a first mass within a cryocooler assembly operatively engaged with a pumphouse; suspending the second mass in relation to the first mass of the assembly; and operatively engaging the second mass as a cold source for a sample chamber. Additional methods can include operatively engaging at least cryofluid of a cryocooler with one or more thermally conductive masses.

Abstract: An optical fiber cable including an optical fiber ribbon in a pipe, wherein the ribbon includes at least two optical fibers arranged side by side, and wherein at least two of the optical fibers are bonded intermittently along a length of the fibers.

Abstract: Disclosed herein are scientific instrument support systems, as well as related methods, apparatus, computing devices, and computer-readable media. In some embodiments, a support apparatus for a scientific instrument includes a processing device and an interface device. The processing device runs a first software module to operate the scientific instrument in a spot mode and in an imaging mode and a second software module to implement spot-mode measurements along a trajectory crossing an edge feature in a sample. The interface device supports communications between the processing device and an acquisition circuit of the scientific instrument. The second software module specifies spot locations and dwell times along the trajectory based on a calibrated disturbance waveform.

Abstract: Systems and methods for performing anticipatory detection of a user's need to be picked up by an autonomous vehicle (AV) are provided. The method may comprise, using a computing device, comprising a processor and a memory, determining a location of an AV, determining whether a pick-up is required at the location, when a pick-up is required at the location, collecting data pertaining to a user and a destination, based on the data, calculating a trigger value indicative of a percent likelihood that a pick-up request is required, determining whether the trigger value is greater than a threshold value, and, when the trigger value is greater than the threshold value, triggering the pick-up, causing the AV to perform the pick-up.

Abstract: Systems and methods facilitate sensing and tallying defecation events of subjects, such as participants in clinical trials for treatments for treating digestive diseases, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and chronic constipation. Systems and methods may also be used by individual patients for sensing and tallying defecation events, and resulting data may be reviewed by a healthcare provider when evaluating patient gastrointestinal health and/or treatments.

Abstract: A method of forming a composition having exfoliated nanoplatelets functionalized with covalently bound surface-modifiers, includes exfoliating a layered nanoclay is exfoliated with a surfactant. The method also includes reacting the exfoliated layered nanoclay with a surface modifier comprising one or more of an epoxide, a silane, or an isocyanate.

Abstract: The technical problem of generating a video feed that represents a user who is party to a video call in a manner that invokes the sense of visual presence of the caller without communicating the live video of the user is addressed by configuring a video calling system to include an avatar call platform. The avatar call platform is configured to generate and display a video of an animated figure that represents a caller during a call, in that the face of the animated figure moves in a way that matches what the caller is saying during the call.

Abstract: An apparatus is disclosed as including a first material volume with at least a hardened portion and a second material volume that includes at least two layers. The first material volume is composed of at least a hardenable alloy of steel. The at least two layers is located adjacent to a first surface comprising the hardened portion of the first material volume. The at least two layers includes a first layer composed of at least a ductile low-carbon alloy of steel and a second layer composed of at least a cobalt-based hardfacing over the first layer. The apparatus is applicable in preparing shear ram blocks and shear ram blades to provide a hardened blade edge with an adjacent hardfacing surface.

Abstract: A method of selecting a wager during a live event on a play by play wagering platform to offer to a user such that a wager includes a win condition, odds, and a wager amount based upon the previous wager history of a user. The user being provided the option to accept or decline the wager as offered.

Abstract: A method of printing on a polymeric article includes applying a decoration-forming deposit on a transfer unit. The method further includes transferring the decoration-forming deposit from the transfer unit to the polymeric article to provide a decoration on the polymeric article.

Abstract: The technical problem of generating a video feed that represents a user who is party to a video call in a manner that invokes the sense of visual presence of the caller without communicating the live video of the user is addressed by configuring a video calling system to include an avatar call platform. The avatar call platform is configured to generate and display a video of an animated figure that represents a caller during a call, in that the face of the animated figure moves in a way that matches what the caller is saying during the call.

Abstract: A method of printing on a polymeric article includes applying a decoration-forming deposit on a transfer blanket. The method further includes transferring the decoration-forming deposit from the transfer unit to the polymeric article to provide a decoration on the polymeric article.

Abstract: Cryocooler assemblies are provided that can include: a first mass configured to generate mechanical responses; a second mass operably engaged with the first mass; and an assembly between the first and second mass, the assembly configured to allow movement of the first mass in relation to the second mass. Methods for isolating mechanical responses within a cryocooler assembly are provided. The methods can include: generating a mechanical response about a first mass within a cryocooler assembly; suspending the first mass in relation to a second mass of the assembly; and operatively engaging the second mass as a cold source for the cryocooler assembly.

Abstract: A method for managing a supply of aerosolisable material for a non-combustible aerosol provision system involves receiving one or more characteristics relating to usage of the non-combustible aerosol provision system. The method also involves predicting a length of time remaining until the supply of aerosolisable material is depleted based on the one or more characteristics relating to usage and an initial supply of aerosolisable material. The method additionally involves taking a pre-emptive action before the supply of aerosolisable material is depleted.

Abstract: A pre-treatment make-up water system and method are provided. The system includes a make-up water line for providing an incoming water source, a nano-filtration system designed to filter the incoming water source, a heat rejection system designed to use the filtered incoming water source as a coolant, and a bypass line in fluid communication with the make-up water line and the heat rejection system, the bypass line designed to supply the incoming water source to the heat rejection system, wherein a tie-in for the bypass line is provided upstream of the nano-filtration system. The system can further include a controller communicatively coupled to one or more components of the system for monitoring and controlling one or more valves, probes, and sensors.

Abstract: This invention provides nonaqueous electrolyte solutions for lithium batteries. The nonaqueous electrolyte solutions comprise a liquid electrolyte medium; a lithium-containing salt; and at least one oxygen-containing brominated flame retardant.