Patents by Inventor Joseph BASCONI

Joseph BASCONI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR REDUCING LOW MOLECULAR WEIGHT SPECIES OF RECOMBINANTLY-PRODUCED PROTEINS
    Publication number: 20240209115
    Abstract: The present invention relates to methods for reducing low molecular weight species of recombinantly-produced proteins. In particular, methods of reducing the formation of low molecular weight species produced by a host cell during the cell culture process through pH control of the production cell culture are disclosed. Also disclosed are methods for reducing or eliminating the generation of alternative splice variants by a host cell during production of a recombinant protein.
    Type: Application
    Filed: April 28, 2022
    Publication date: June 27, 2024
    Applicants: AMGEN INC., AMGEN RESEARCH (MUNICH) GmbH
    Inventors: Anika MENTHE, Joseph BASCONI, Nitya M. JACOB, Russell JAMPOL, Huong Thi Ngoc LE, Kim LE, Jessica PEDROSO, Jennitte STEVENS, Sreekanth SURAVAJJALA, Charilyn TEJAMO, Pheng YAM