Patents by Inventor Joseph BAUR

Joseph BAUR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for enhancing liver regeneration
    Patent number: 11559522
    Abstract: The invention includes methods, kits, and pharmaceutical compositions for enhancing liver regeneration in a mammal in need thereof, comprising administering a therapeutically effective amount of an agent that increases nicotinamide adenine dinucleotide (NAD) activity. The methods may include administering a therapeutically effective amount of an agent that increases nicotinamide adenine dinucleotide (NAD) activity and a sirtuin 1 (Sirt1) agonist. The agent that increases NAD activity may be a NAD precursor. The NAD precursor may include one or more of tryptophan, nicotinic acid, nicotinic acid riboside, nicotinamide riboside (NR), nicotinamide, NADP, and NAD itself, and a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: July 26, 2021
    Date of Patent: January 24, 2023
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Joseph Baur, Sarmistha Mukherjee
  • METHODS FOR ENHANCING LIVER REGENERATION
    Publication number: 20210346365
    Abstract: The invention includes methods, kits, and pharmaceutical compositions for enhancing liver regeneration in a mammal in need thereof, comprising administering a therapeutically effective amount of an agent that increases nicotinamide adenine dinucleotide (NAD) activity. The methods may include administering a therapeutically effective amount of an agent that increases nicotinamide adenine dinucleotide (NAD) activity and a sirtuin 1 (Sirt1) agonist. The agent that increases NAD activity may be a NAD precursor. The NAD precursor may include one or more of tryptophan, nicotinic acid, nicotinic acid riboside, nicotinamide riboside (NR), nicotinamide, NADP, and NAD itself, and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: July 26, 2021
    Publication date: November 11, 2021
    Applicant: The Trustees of the Universtiy of Pennsylvania
    Inventors: Joseph BAUR, Sarmistha Mukherjee
  • Methods for enhancing liver regeneration
    Patent number: 11103496
    Abstract: The invention includes methods, kits, and pharmaceutical compositions for enhancing liver regeneration in a mammal in need thereof, comprising administering a therapeutically effective amount of an agent that increases nicotinamide adenine dinucleotide (NAD) activity. The methods may include administering a therapeutically effective amount of an agent that increases nicotinamide adenine dinucleotide (NAD) activity and a sirtuin 1 (Sirt1) agonist. The agent that increases NAD activity may be a NAD precursor. The NAD precursor may include one or more of tryptophan, nicotinic acid, nicotinic acid riboside, nicotinamide riboside (NR), nicotinamide, NADP, and NAD itself and a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: August 31, 2021
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Joseph Baur, Sarmistha Mukherjee
  • METHODS FOR ENHANCING LIVER REGENERATION
    Publication number: 20190099409
    Abstract: The invention includes methods, kits, and pharmaceutical compositions for enhancing liver regeneration in a mammal in need thereof, comprising administering a therapeutically effective amount of an agent that increases nicotinamide adenine dinucleotide (NAD) activity. The methods may include administering a therapeutically effective amount of an agent that increases nicotinamide adenine dinucleotide (NAD) activity and a sirtuin 1 (Sirt1) agonist. The agent that increases NAD activity may be a NAD precursor. The NAD precursor may include one or more of tryptophan, nicotinic acid, nicotinic acid riboside, nicotinamide riboside (NR), nicotinamide, NADP, and NAD itself and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: February 22, 2017
    Publication date: April 4, 2019
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Joseph BAUR, Sarmistha MUKHERJEE
  • XENOHORMESIS BASED COMPOSITIONS AND METHODS
    Publication number: 20100242139
    Abstract: The present invention provides methods and compositions for improving the health of subjects, such as their resistance to stress.
    Type: Application
    Filed: January 12, 2007
    Publication date: September 23, 2010
    Applicant: President and Fellows of Harvard College
    Inventors: David A. Sinclair, Joseph A. Baur, Sean M. Armour
  • Methods and Compositions for Treatment Cell Proliferative Disorders
    Publication number: 20090182003
    Abstract: The present invention provides methods for treating and preventing cell proliferative disorders and conditions comprising administering to a subject resveratrol or an analog thereof.
    Type: Application
    Filed: January 12, 2007
    Publication date: July 16, 2009
    Applicant: President and Fellows of Harvard College
    Inventors: David A. Sinclair, Joseph A. Baur, Sean M. Armour