Abstract: Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries without the administration of a hyperemic agent.

Abstract: Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries without the administration of a hyperemic agent.

Abstract: Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries without the administration of a hyperemic agent. In some embodiments, the devices, systems, and methods of the present disclosure are configured to assess a vessel by automatically correcting for drift in the equipment utilized to obtain measurements related to the vessel.

Abstract: Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed.

Abstract: The invention generally relates to systems and methods for determining coronary flow reserve (CFR). The invention provides systems and methods for determining coronary flow reserve using a flow reserve index obtained at rest and during hyperemia. One flow reserve index obtained under the two conditions can be used to compute coronary flow reserve. The difference between the resting value and the hyperemic value of the index correlates to a coronary flow reserve value.

Abstract: The invention generally relates to an auxiliary guidewire for an intravascular procedure. The invention provides an auxiliary guidewire that slips over a primary guidewire and can provide a very fine extension beyond the end of the primary guidewire. The primary guidewire can be taken to its limit within the fine vasculature, and the auxiliary guidewire can then extend further into the fine vasculature. The primary guidewire can be taken to a bifurcation. The primary guidewire and the auxiliary guidewire can be sent down separate branches of the bifurcation. A physician can select which of the primary guidewire and the auxiliary guidewire are within the branch that needs to be treated by, for example, consulting an angiography display.

Abstract: The invention generally relates to systems and methods for predicting impact of a catheter on curvature of a vessel. In certain aspects, the invention provides a system for predicting impact of a catheter on curvature of a vessel. The system includes a central processing unit (CPU) and storage coupled to the CPU for storing instructions. The stored instructions, when executed by the CPU, cause the CPU to accept as input data representative of stiffness of a catheter. The CPU is additionally caused to compare the data to a material parameters data set. The material parameters data set includes vessel displacement values for catheters of different stiffness. The CPU is additionally caused to predict impact of the catheter on a curvature of a vessel based on the comparison of the data to the material parameters data set, and to provide the prediction as an output.

Abstract: Systems and methods for obtaining and processing data collected using a multi-site intravascular sensing device are provided. Some embodiments are directed to locating a structure within a vessel and performing an examination of the structure once it has been located. In one embodiment, an elongate member has a plurality of sensors and set of measurements is obtained using the plurality of sensors, the set of measurements including at least one measurement from each sensor of the plurality of sensors. The various sensor measurements are compared and a difference in a vascular characteristic is determined from the compared measurements. The location of the structure may be determined based on the adjacent sensors.

Abstract: Systems and methods for aiding users in viewing, assessing and analyzing images, especially images of lumens and medical devices contained within the lumens. Systems and methods for interacting with images of lumens and medical devices, for example through a graphical user interface.