Patents by Inventor Joseph C. Loftus

Joseph C. Loftus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of sensitizing a patient with glioma to a therapeutic agent by administering small hairpin RNA targeting PDZ-RHOGEF
    Patent number: 10624895
    Abstract: The technology encompasses methods of treating a patient with cancer, such as glioblastoma. The methods may include the administration of one or more pharmaceutical compositions that are capable of inhibiting TROY to treat the patient with cancer.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: April 21, 2020
    Assignees: The Translational Genomics Research Institute, Mayo Foundation for Medical Education and Research
    Inventors: Nhan Tran, Joseph C. Loftus, Harshil Dhruv
  • Methods used to treat cancer
    Patent number: 10426777
    Abstract: The invention encompasses methods of treating a patient with cancer, such as glioblastoma. The methods may include the administration of one or more pharmaceutical compositions that are capable of inhibiting TROY to treat the patient with cancer.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: October 1, 2019
    Assignees: The Translational Genomics Research Institute, Mayo Foundation for Medical Education and Research
    Inventors: Nhan Tran, Joseph C. Loftus, Harshil Dhruv
  • METHODS USED TO TREAT CANCER
    Publication number: 20190054089
    Abstract: The technology encompasses methods of treating a patient with cancer, such as glioblastoma. The methods may include the administration of one or more pharmaceutical compositions that are capable of inhibiting TROY to treat the patient with cancer.
    Type: Application
    Filed: April 8, 2016
    Publication date: February 21, 2019
    Inventors: Nhan Tran, Joseph C. Loftus, Harshil Dhruv
  • METHODS USED TO TREAT CANCER
    Publication number: 20180092922
    Abstract: The invention encompasses methods of treating a patient with cancer, such as glioblastoma. The methods may include the administration of one or more pharmaceutical compositions that are capable of inhibiting TROY to treat the patient with cancer.
    Type: Application
    Filed: December 14, 2017
    Publication date: April 5, 2018
    Inventors: Nhan Tran, Joseph C. Loftus, Harshil Dhruv
  • Methods of using propentofylline to treat glioma and glioblastoma
    Patent number: 9872857
    Abstract: The invention encompasses methods of treating a patient with cancer, such as glioblastoma. The methods may include the administration of one or more pharmaceutical compositions that are capable of inhibiting TROY to treat the patient with cancer.
    Type: Grant
    Filed: March 14, 2016
    Date of Patent: January 23, 2018
    Assignees: The Translational Genomics Research Institutet, Mayo Foundation for Medical Education and Research
    Inventors: Nhan Tran, Joseph C. Loftus, Harshil Dhruv
  • Anti-Pyk2 antibodies
    Patent number: 8552155
    Abstract: This document provides methods and materials related to anti-Pyk2 antibodies. For example, anti-Pyk2 antibodies, methods for making anti-Pyk2 antibodies, and methods for using an anti-Pyk2 antibody to inhibit glioma cell migration are provided.
    Type: Grant
    Filed: May 28, 2009
    Date of Patent: October 8, 2013
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Christopher A. Lipinski, Joseph C. Loftus
  • ANTI-PYK2 ANTIBODIES
    Publication number: 20110136232
    Abstract: This document provides methods and materials related to anti-Pyk2 antibodies. For example, anti-Pyk2 antibodies, methods for making anti-Pyk2 antibodies, and methods for using an anti-Pyk2 antibody to inhibit glioma cell migration are provided.
    Type: Application
    Filed: May 28, 2009
    Publication date: June 9, 2011
    Inventors: Christopher A. Lipinski, Joseph C. Loftus
  • Peptides and antibodies that inhibit platelet adhesion
    Patent number: 5498499
    Abstract: A polypeptide analog capable of immunologically mimicking a linear hGPIIb antigenic determinant expressed when platelet-associated GPIIb-IIIa binds fibrinogen is disclosed. An antibody that immunoreacts with the polypeptide and hGPIIb when hGPIIb is present as a platelet-associated GPIIb-IIIa/fibrinogen complex is also disclosed. Further disclosed are diagnostic systems and methods for assaying fibrinogen-bound platelets in a vascular fluid sample using the polypeptides and/or antibodies of the invention.
    Type: Grant
    Filed: May 15, 1992
    Date of Patent: March 12, 1996
    Assignee: The Scripps Research Institute
    Inventors: Edward F. Flow, Mark H. Ginsberg, Joseph C. Loftus