Patents by Inventor Joseph Charles Salamone
Joseph Charles Salamone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11839626Abstract: Antimicrobial polymer coating formulations are prepared that protect biological surfaces by treating, reducing, ameliorating, preventing or inhibiting pathogenic microorganism ingress to a human or animal host, reducing the potential for infection, particularly by necrotizing fasciitis originating microorganisms, through use of a polymer coating barrier containing antimicrobial agents that facilitates sustained release of biocidal agents active against such opportunistic microorganisms. Such formulations are effective for inhibiting microbial ingress pertaining to soft tissue and skin tears, abrasions, punctures and surgical wounds, and can be used as in water environments and as a skin protectant sunscreen and insect repellent.Type: GrantFiled: September 1, 2017Date of Patent: December 12, 2023Assignee: ROCHAL TECHNOLOGIES LLCInventors: Joseph Charles Salamone, Katelyn Elizabeth Reilly, Ronald Thomas Nixon, Ann Beal Salamone, Kelly Xiaoyu-Chen Leung
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Patent number: 11590259Abstract: This invention relates generally to water-insoluble but water-swellable and deformable crosslinked PEGylated microgel particles of proteins and protein-based macromolecules that are pseudoplastic (shear thinning) and flow in aqueous media under shear and which can be injected or made to flow, wherein said microgel particles can reform as a cluster of microgel particles when shearing forces are removed. The microgel particles function as a matrix to support cell growth, viability, and proliferation.Type: GrantFiled: June 15, 2021Date of Patent: February 28, 2023Assignee: ROCHAL TECHNOLOGIES LLCInventors: Joseph Charles Salamone, Ann Beal Salamone, Katelyn Elizabeth Reilly, Laura Jean Suggs, Eunna Chung, Kelly Xiaoyu-Chen Leung
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Publication number: 20210308323Abstract: This invention relates generally to water-insoluble but water-swellable and deformable crosslinked PEGylated microgel particles of proteins and protein-based macromolecules that are pseudoplastic (shear thinning) and flow in aqueous media under shear and which can be injected or made to flow, wherein said microgel particles can reform as a cluster of microgel particles when shearing forces are removed. The microgel particles function as a matrix to support cell growth, viability, and proliferation.Type: ApplicationFiled: June 15, 2021Publication date: October 7, 2021Applicant: ROCHAL INDUSTRIES, LLCInventors: Joseph Charles SALAMONE, Ann Beal SALAMONE, Katelyn Elizabeth REILLY, Laura Jean SUGGS, Eunna CHUNG, Kelly Xiaoyu-Chen LEUNG
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Patent number: 10688159Abstract: A treatment for pruritus is described that is based upon amylase. The amylases (?-, ?-, ?-amylase) are noted for the cleavage of the ?-glycosidic bonds of polysaccharides, yielding lower molecular weight carbohydrate/sugar fragments. It has now been found that ?-amylase is effective in the reduction of pruritus (itching) of affected tissue.Type: GrantFiled: March 23, 2016Date of Patent: June 23, 2020Assignee: ROCHAL INDUSTRIES, LLCInventors: Joseph Charles Salamone, Ann Beal Salamone, Kelly Xiaoyu Chen Leung, Katelyn Elizabeth Reilly
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Patent number: 10238719Abstract: A debridement enzyme for necrotic tissue is described that is not dependent upon proteolytic enzymatic activity but instead utilizes the amylase family of enzymes. The amylases (?-, ?-, ?-amylase) are noted for the cleavage of the ?-glycosidic bonds of polysaccharides, yielding lower molecular weight carbohydrate/sugar fragments. It has now been found that ?-amylase is effective in the debridement of devitalized tissue.Type: GrantFiled: January 24, 2017Date of Patent: March 26, 2019Assignee: ROCHAL INDUSTRIES, LLCInventors: Joseph Charles Salamone, Kelly Xiaoyu Chen Leung, Ann Beal Salamone, Katelyn Elizabeth Reilly
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Publication number: 20170360825Abstract: Antimicrobial polymer coating formulations are prepared that protect biological surfaces by treating, reducing, ameliorating, preventing or inhibiting pathogenic microorganism ingress to a human or animal host, reducing the potential for infection, particularly by necrotizing fasciitis originating microorganisms, through use of a polymer coating barrier containing antimicrobial agents that facilitates sustained release of biocidal agents active against such opportunistic microorganisms. Such formulations are effective for inhibiting microbial ingress pertaining to soft tissue and skin tears, abrasions, punctures and surgical wounds, and can be used as in water environments and as a skin protectant sunscreen and insect repellent.Type: ApplicationFiled: September 1, 2017Publication date: December 21, 2017Applicant: ROCHAL INDUSTRIES, LLCInventors: Joseph Charles SALAMONE, Katelyn Elizabeth REILLY, Ronald Thomas NIXON, Ann Beal SALAMONE, Kelly Xiaoyu-Chen LEUNG
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Publication number: 20170151314Abstract: A debridement enzyme for necrotic tissue is described that is not dependent upon proteolytic enzymatic activity but instead utilizes the amylase family of enzymes. The amylases (?-, ?-, ?-amylase) are noted for the cleavage of the ?-glycosidic bonds of polysaccharides, yielding lower molecular weight carbohydrate/sugar fragments. It has now been found that ?-amylase is effective in the debridement of devitalized tissue.Type: ApplicationFiled: January 24, 2017Publication date: June 1, 2017Inventors: Joseph Charles Salamone, Kelly Xiaoyu Chen Leung, Ann Beal Salamone, Katelyn Elizabeth Reilly
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Patent number: 9592280Abstract: A debridement enzyme for necrotic tissue is described that is not dependent upon proteolytic enzymatic activity but instead utilizes the amylase family of enzymes. The amylases (?-, ?-, ?-amylase) are noted for the cleavage of the ?-glycosidic bonds of polysaccharides, yielding lower molecular weight carbohydrate/sugar fragments. It has now been found that ?-amylase is effective in the debridement of devitalized tissue.Type: GrantFiled: October 10, 2014Date of Patent: March 14, 2017Assignee: ROCHAL INDUSTRIES LLCInventors: Joseph Charles Salamone, Kelly Xiaoyu Chen Leung, Ann Beal Salamone, Katelyn Elizabeth Reilly
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Publication number: 20160303281Abstract: This invention relates generally to water-insoluble but water-swellable and deformable crosslinked PEGylated microgel particles of proteins and protein-based macromolecules that are pseudoplastic (shear thinning) and flow in aqueous media under shear and which can be injected or made to flow, wherein said microgel particles can reform as a duster of microgel particles when shearing forces are removed. The microgel particles function as a matrix to support cell growth, viability, and proliferation.Type: ApplicationFiled: April 17, 2015Publication date: October 20, 2016Applicant: ROCHAL INDUSTRIES, LLCInventors: Joseph Charles Salamone, Ann Beal Salamone, Katelyn Elizabeth Reilly, Laura Jean Suggs, Eunna Chung, Kelly Xiaoyu-Chen Leung
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Publication number: 20160199459Abstract: A treatment for pruritus is described that is based upon amylase. The amylases (?-, ?-, ?-amylase) are noted for the cleavage of the ?-glycosidic bonds of polysaccharides, yielding lower molecular weight carbohydrate/sugar fragments. It has now been found that ?-amylase is effective in the reduction of pruritus (itching) of affected tissue.Type: ApplicationFiled: March 23, 2016Publication date: July 14, 2016Inventors: Joseph Charles SALAMONE, Ann Beal SALAMONE, Kelly Xiaoyu Chen LEUNG, Katelyn Elizabeth REILLY
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Publication number: 20160101165Abstract: A debridement enzyme for necrotic tissue is described that is not dependent upon proteolytic enzymatic activity but instead utilizes the amylase family of enzymes. The amylases (?-, ?-, ?-amylase) are noted for the cleavage of the ?-glycosidic bonds of polysaccharides, yielding lower molecular weight carbohydrate/sugar fragments. It has now been found that ?-amylase is effective in the debridement of devitalized tissue.Type: ApplicationFiled: October 10, 2014Publication date: April 14, 2016Inventors: Joseph Charles SALAMONE, Kelly Xiaoyu Chen LEUNG, Ann Beal SALAMONE, Katelyn Elizabeth REILLY
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Publication number: 20160101166Abstract: A treatment for pruritus is described that is based upon amylase. The amylases (?-, ?-, ?-amylase) are noted for the cleavage of the ?-glycosidic bonds of polysaccharides, yielding lower molecular weight carbohydrate/sugar fragments. It has now been found that ?-amylase is effective in the reduction of pruritus (itching) of affected tissue.Type: ApplicationFiled: October 10, 2014Publication date: April 14, 2016Inventors: Joseph Charles SALAMONE, Ann Beal SALAMONE, Kelly Xiaoyu Chen LEUNG, Katelyn Elizabeth REILLY
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Publication number: 20160095876Abstract: Antimicrobial polymer coating formulations are prepared that protect biological surfaces by treating, reducing, ameliorating, preventing or inhibiting pathogenic microorganism ingress to a human or animal host, reducing the potential for infection, particularly by necrotizing fasciitis originating microorganisms, through use of an polymer coating barrier containing antimicrobial agents that facilitates sustained release of biocidal agents active against such opportunistic microorganisms. Such formulations are effective for inhibiting microbial ingress pertaining to soft tissue and skin tears, abrasions, punctures and surgical wounds, and can be used as in water environments and as a skin protectant sunscreen and insect repellent.Type: ApplicationFiled: October 1, 2014Publication date: April 7, 2016Inventors: Joseph Charles SALAMONE, Katelyn Elizabeth REILLY, Ronald Thomas NIXON, Ann Beal SALAMONE, Kelly Xiaoyu-Chen LEUNG
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Patent number: 8877882Abstract: Liquid adhesive coating materials are prepared that protect surfaces, such as medical devices and biological surfaces, including skin and mucous membranes, from pressure, shear, and friction. The liquid coating materials utilize an amphiphilic siloxysilane/hydroxyalkyl ester polymer-containing coating material dissolved in a volatile solvent, with or without an antimicrobial agent, where when the polymer coating is formed after solvent evaporation and is folded against itself or placed against another material, the surface of said coating does not adhere, while the bottom of the coating remains attached to the original surface.Type: GrantFiled: October 4, 2013Date of Patent: November 4, 2014Assignee: Rochal Industries LLPInventors: Joseph Charles Salamone, Katelyn Elizabeth Reilly, Ann Beal Salamone, Xiaoyu Chen
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Patent number: 8852648Abstract: A composition and method adapted for delivery of hydrophilic, biologically-active agents are disclosed. The composition can include a reverse microemulsion formed from at least one hydrophilic, biologically-active agent solubilized by a hydrophobic reverse emulsion surfactant in a non-stinging, volatile, hydrophobic solvent. The non-stinging, volatile, hydrophobic solvent is selected from the group consisting of volatile linear and cyclic siloxanes, volatile linear, branched, and cyclic alkanes, volatile fluorocarbons and chlorofluorocarbons, liquid carbon dioxide under pressure, and combinations thereof. The reverse microemulsion can be an optically clear solution.Type: GrantFiled: October 21, 2013Date of Patent: October 7, 2014Assignee: Rochal Industries, LLPInventors: Joseph Charles Salamone, Xiaoyu Chen, Ann Beal Salamone, Katelyn Elizabeth Reilly
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Publication number: 20140127320Abstract: A composition and method adapted for delivery of hydrophilic, biologically-active agents are disclosed. The composition can include a reverse microemulsion formed from at least one hydrophilic, biologically-active agent solubilized by a hydrophobic reverse emulsion surfactant in a non-stinging, volatile, hydrophobic solvent. The non-stinging, volatile, hydrophobic solvent is selected from the group consisting of volatile linear and cyclic siloxanes, volatile linear, branched, and cyclic alkanes, volatile fluorocarbons and chlorofluorocarbons, liquid carbon dioxide under pressure, and combinations thereof. The reverse microemulsion can be an optically clear solution.Type: ApplicationFiled: October 21, 2013Publication date: May 8, 2014Applicant: ROCHAL INDUSTRIES, LLPInventors: Joseph Charles Salamone, Xiaoyu Chen, Ann Beal Salamone, Katelyn Elizabeth Reilly