Patents by Inventor Joseph Contessa

Joseph Contessa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10765638
    Abstract: Compositions and methods for efficient delivery of therapeutic agents in vivo are provided. Typically, the compositions are in the form of polymeric particles formed from one or more therapeutic agent complexed with a polycationic polymer which is further encapsulated in one or more amphiphilic polymers, preferably diblock copolymer of a polyalkylene oxide and a polyester such as poly(D,L-lactide)-poly(ethylene glycol) (PLA-PEG). In the preferred embodiments, the chemotherapeutic agent reduces, or inhibits N-glycosylation of one or more receptor tyrosine kinases of cancer cells. Methods of using the particles to treat cancer are also provided.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: September 8, 2020
    Assignee: YALE UNIVERSITY
    Inventors: W. Mark Saltzman, Joseph Contessa, Amanda King
  • Publication number: 20190133962
    Abstract: Compositions and methods for efficient delivery of therapeutic agents in vivo are provided. Typically, the compositions are in the form of polymeric particles formed from one or more therapeutic agent complexed with a polycationic polymer which is further encapsulated in one or more amphiphilic polymers, preferably diblock copolymer of a polyalkylene oxide and a polyester such as poly(D,L-lactide)-poly(ethylene glycol) (PLA-PEG). In the preferred embodiments, the chemotherapeutic agent reduces, or inhibits N-glycosylation of one or more receptor tyrosine kinases of cancer cells. Methods of using the particles to treat cancer are also provided.
    Type: Application
    Filed: November 2, 2018
    Publication date: May 9, 2019
    Inventors: W. Mark Saltzman, Joseph Contessa, Amanda King
  • Patent number: D764930
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: August 30, 2016
    Assignee: Hex Performance, LLC
    Inventors: Joseph Contessa, Drew Westervelt, Andrew C. White
  • Patent number: D785462
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: May 2, 2017
    Assignee: HEX PERFORMANCE, LLC
    Inventors: Joseph Contessa, Drew Westervelt, Andrew C. White
  • Patent number: D795703
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: August 29, 2017
    Assignee: Hex Performance, LLC
    Inventors: Joseph Contessa, Drew Westervelt, Andrew C. White