Patents by Inventor Joseph D. Fondell

Joseph D. Fondell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid molecules encoding nuclear hormone receptor coactivators and uses thereof
    Patent number: 6248520
    Abstract: Isolated nucleic acid molecules encoding Thyroid Receptor-Associated Proteins (TRAPS) are provided. TRAPS are members of protein complexes that bind to nuclear hormone receptors in a ligand-dependent manner so that the receptor, upon activation by a corresponding hormone, regulates the transcription of a particular gene. Also provided are methods of replicating and expressing such isolated nucleic acid molecules, pharmaceutical compositions comprising TRAPS, and methods of modulating gene expression via administration of therapeutically effective amounts of such pharmaceutical compositions.
    Type: Grant
    Filed: July 6, 1998
    Date of Patent: June 19, 2001
    Assignee: The Rockefeller University
    Inventors: Robert G. Roeder, Joseph D. Fondell, Chao Xingyuan, Mitsuhiro Ito