Patents by Inventor Joseph D. Irr

Joseph D. Irr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Blood cryopreservation container
    Patent number: 5250044
    Abstract: This invention relates to bags for the cryopreservation of mammalian cells and particularly for the long-term freezing of red blood cell. This invention also relates to methods of manufacturing such bags.
    Type: Grant
    Filed: February 6, 1990
    Date of Patent: October 5, 1993
    Assignee: Du Pont Merck Pharmaceutical Company
    Inventors: Joseph D. Irr, John D. Walker
  • Blood cryopreservation container
    Patent number: 5209745
    Abstract: This invention relates to containers for the cryopreservation of mammalian cells and particularly for the long-term freezing of red blood cell. This invention also relates to methods of manufacturing such containers.
    Type: Grant
    Filed: October 23, 1990
    Date of Patent: May 11, 1993
    Inventors: Joseph D. Irr, John D. Walker, George F. Dunn, Jr., Viet X. Nguyen
  • Dot matrix membrane cell expansion
    Patent number: 5139946
    Abstract: There is disclosed a perfusable cell culture device capable of expansion and maintenance of biological cells, including mammalian, microbial, plant and insect cells in culture. The device comprises an upper and lower polymeric film layer and a gas and liquid permeable flow divider membrane. The flow divider membrane is affixed between the upper and lower polymeric layers and to the lower polymeric layer in a manner providing channels for fluid distribution of culture medium which is perfused at a controlled rate, uniformly across the flow divider membrane and to a bed of cells dispersed on the flow divider membrane.
    Type: Grant
    Filed: July 9, 1991
    Date of Patent: August 18, 1992
    Assignee: Du Pont Merck Pharmaceutical Company
    Inventors: Gary W. Howell, Joseph D. Irr, Ara T. Nahapetian
  • Enhances LAK cell activation by treatment of human peripheral blood mononuclear cells with amino acid amides
    Patent number: 5108760
    Abstract: There is provided an improved process for enhanced LAK cell activation wherein the peripheral blood mononuclear cells are treated with an amino acid amide to yield depletion, prior to the lymphocytes being cultured at high density. Also provided are pharmaceutical compositions and methods of using them in combination with IL-2 to treat cancer in a mammal.
    Type: Grant
    Filed: July 21, 1989
    Date of Patent: April 28, 1992
    Assignee: Terumo Corporation
    Inventors: Joseph D. Irr, Kam Leung
  • Dot matrix membrane cell expansion and maintenance vessel
    Patent number: 5068195
    Abstract: There is disclosed a perfusable cell culture device capable of expansion and maintenance of biological cells, including mammalian, microbial, plant and insect cells in culture. The device comprises an upper and lower polymeric film layer and a gas and liquid permeable flow divider membrane. The flow divider membrane is affixed between the upper and lower polymeric layers and to the lower polymeric layer in a manner providing channels for fluid distribution of culture medium which is perfused at a controlled rate, uniformly across the flow divider membrane and to a bed of cells dispersed on the flow divider membrane.
    Type: Grant
    Filed: November 2, 1988
    Date of Patent: November 26, 1991
    Assignee: Du Pont Merck Pharmaceutical Company
    Inventors: Gary W. Howell, Joseph D. Irr, Ara T. Nahapetian
  • Simplified method for the preparation of human lymphokine activated killer cells
    Patent number: 4808151
    Abstract: A lymphocyte-containing white blood cell fraction obtained by standard leukapheresis, elutriation leukapheresis or standard centrifugation can be used for production of lymphokine activated killer cells by incubation with IL-2. Removal of red blood cells and granulocytes by centrifugation on ficoll is not necessary.
    Type: Grant
    Filed: April 27, 1987
    Date of Patent: February 28, 1989
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: George F. Dunn, Jr., Joseph D. Irr, Lise N. Halpern