Abstract: Systems and methods are provided for measuring electrical activity within a brain of a patient. An electrode array is configured to take measurements of electrical potential as raw electroencephalographic (EEG) data. A data processing component includes a spectral decomposition component configured to divide the raw EEG data into a plurality of frequency intervals, within a total range of frequencies and an inverse solution component configured to transform the raw EEG data associated with each frequency interval into a spatial mapping of electrical activity as to provide a set of parameters, with each parameter representing an average electrical activity at an associated location within the brain over an epoch of interest.

Abstract: The present invention describes a method and apparatus to localize the electrical signals measured from a subject's scalp surface, preferably in near-real time, and to generate dynamic three-dimensional information of the electrical activity occurring within the cerebral cortex of the brain. In the preferred embodiment, it can produce images that can be immediately inspected and analyzed by an operator in near-real time, resulting in a powerful new cortical imaging modality, which we denote as Dynamic Electrocortical Imaging (DECI). The present invention involves the use of a computer, an electroencephalographic (EEG) amplifier, EEG electrodes, and custom software. It can measure healthy and diseased cortical events and states in both conscious and unconscious subjects.

Abstract: An apparatus for exerting force on a subject tissue includes a linear motor for generating a force according to a predetermined force profile incorporating at least one motion control parameter. The linear motor is directly coupled to a motor output member to drivingly produce linear motion of the motor output member under direction of a motor controller executing the predetermined force profile. A tissue-contacting member is connected to the motor output member for directly proportional linear motion therewith. A load cell provides load cell feedback to the motor controller. The motor controller adjusts the motion of the motor output member responsive to the load cell feedback to substantially conform the motion to the predetermined force profile. The linear motor moves the tissue-contacting member to contact the subject tissue according to the predetermined force profile and responsively initiate a subject reaction to the exerted force.

Abstract: Systems and methods are provided for measuring electrical activity within a brain of a patient. An electrode array is configured to take measurements of electrical potential as raw electroencephalographic (EEG) data. A data processing component includes a spectral decomposition component configured to divide the raw EEG data into a plurality of frequency intervals, within a total range of frequencies and an inverse solution component configured to transform the raw EEG data associated with each frequency interval into a spatial mapping of electrical activity as to provide a set of parameters, with each parameter representing an average electrical activity at an associated location within the brain over an epoch of interest.

Abstract: An apparatus for exerting force on a subject tissue includes a linear motor for generating a force according to a predetermined force profile incorporating at least one motion control parameter. The linear motor is directly coupled to a motor output member to drivingly produce linear motion of the motor output member under direction of a motor controller executing the predetermined force profile. A tissue-contacting member is connected to the motor output member for directly proportional linear motion therewith. A load cell provides load cell feedback to the motor controller. The motor controller adjusts the motion of the motor output member responsive to the load cell feedback to substantially conform the motion to the predetermined force profile. The linear motor moves the tissue-contacting member to contact the subject tissue according to the predetermined force profile and responsively initiate a subject reaction to the exerted force.

Abstract: The present invention describes a method and apparatus to localize the electrical signals measured from a subject's scalp surface, preferably in near-real time, and to generate dynamic three-dimensional information of the electrical activity occurring within the cerebral cortex of the brain. In the preferred embodiment, it can produce images that can be immediately inspected and analyzed by an operator in near-real time, resulting in a powerful new cortical imaging modality, which we denote as Dynamic Electrocortical Imaging (DECI). The present invention involves the use of a computer, an electroencephalographic (EEG) amplifier, EEG electrodes, and custom software. It can measure healthy and diseased cortical events and states in both conscious and unconscious subjects.