Patents by Inventor Joseph D. Shore

Joseph D. Shore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide mediated enhancement of thrombolysis methods and compositions
    Patent number: 5639726
    Abstract: The invention relates generally to peptides which decrease the half-life of active plasminogen activator inhibitor-1. This invention further relates to methods and compositions for using peptides which decrease the half-life of active plasminogen activator inhibitor-1. Further, the invention includes methods and compositions useful in clot lysis.
    Type: Grant
    Filed: September 30, 1994
    Date of Patent: June 17, 1997
    Assignees: The Regents of the University of Michigan, Henry Ford Health System
    Inventors: Daniel A. Lawrence, David Ginsburg, Joseph D. Shore, William P. Fay, Steven T. Olson, Ann Marie Francis-Chmura, Daniel T. Eitzman, Dell Paielli
  • Active site labelling of plasminogen
    Patent number: 5187069
    Abstract: A plasminogen, which has a label incorporated into an active site thereof such that said plasminogen is enzymatically and catalytically inactive upon its conversion to plasmin, and an enzymatically and catalytically inactive plasmin with a label incorporated into an active site thereof.A method of making a labelled plasminogen which is enzymatically and catalytically inactive upon conversion to plasmin is provided along with an assay method which utilizes a labelled plasminogen.
    Type: Grant
    Filed: August 6, 1990
    Date of Patent: February 16, 1993
    Assignee: Henry Ford Health System
    Inventors: Joseph D. Shore, Paul E. Bock, Steven T. Olson, Duane E. Day