Abstract: A thrombectomy system including a delivery catheter configured to support one or more thrombectomy instruments. The delivery catheter includes a delivery catheter hub and a deliver catheter having a collection shaft with a collection lumen. An aspiration flush valve includes an aspiration port, a flushing port and an outlet port in communication with the collection lumen. The outlet port is in selective communication with the aspiration port and the flushing port. A valve operator is movable relative to the aspiration, flushing and outlet ports. The valve operator includes flushing and aspiration configurations. In the flushing configuration the outlet port is in communication with the flushing port. In the aspiration configuration the outlet port is in communication with the aspiration port.