Abstract: A method for obtaining quantitative compositional information from a multilayer web containing a highly light-scattering component. The compositional information is obtained by measuring and analyzing the transmitted or diffusely reflected infrared spectrum. The method allows for separately determining the moisture content of hydrophobic (non-hydrogen bonding) layers and hydrophilic (hydrogen bonding) layers of multilayer webs. The separate measurements of moisture content can be made simultaneously in moving webs having both types of layers present. The method is used to determine further compositional information such as the thickness of the individual support and gelatin containing layers, plasticizer content, retained solvents content, and the presence of other components in webs, especially photographic webs.