Patents by Inventor Joseph E. Rice

Joseph E. Rice has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic compounds
    Patent number: 8993607
    Abstract: The invention provides compounds of formula I, II, and III as defined herein, as well as salts thereof. The compounds may have activity as anti-proliferative agents.
    Type: Grant
    Filed: August 1, 2008
    Date of Patent: March 31, 2015
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Edmond J. LaVoie, Joseph E. Rice
  • Therapeutic compounds
    Patent number: 8796300
    Abstract: The invention provides compounds of formula (I) wherein u, d, v, m, n, R1, W, X, Y, and Z have any values defined herein, as well as salts thereof. The compounds have activity as anti-proliferative agents.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: August 5, 2014
    Assignees: Rutgers, the State University of New Jersey, University of Medicine and Dentistry of New Jersey
    Inventors: Edmond J. LaVoie, Joseph E. Rice, Suzanne G. Rzuczek, Daniel S. Pilch
  • Macrocyclic polyoxazole compounds and use thereof
    Patent number: 8729060
    Abstract: The invention provides compounds of formula (I) wherein A, B, R1, F, G, n, n? and the dotted line have any values defined herein, as well as salts thereof. The compounds have activity as anti-proliferative agents.
    Type: Grant
    Filed: August 1, 2008
    Date of Patent: May 20, 2014
    Assignee: Rutgers, the State University of New Jersey
    Inventors: Edmond J. LaVoie, Joseph E. Rice, Satyanarayana Mavurapu
  • Therapeutic compounds
    Patent number: 8518928
    Abstract: The invention provides compounds of formula I: wherein A, B, D, E, R1, R2, R3, R4, R5, X, and - - - have any values defined herein, as well as salts thereof. The compounds have activity as G-quadruplex DNA stabilizers and as anti-proliferative agents.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: August 27, 2013
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Edmond J. Lavoie, Joseph E. Rice, Leroy F. Liu
  • THERAPEUTIC COMPOUNDS
    Publication number: 20120238595
    Abstract: The invention provides compounds of formula (I) wherein u, d, v, m, n, R1, W, X, Y, and Z have any values defined herein, as well as salts thereof. The compounds have activity as anti-proliferative agents.
    Type: Application
    Filed: November 5, 2010
    Publication date: September 20, 2012
    Applicants: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY, RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Edmond J. LaVoie, Joseph E. Rice, Suzanne G. Rzuczek, Daniel S. Pilch
  • THERAPEUTIC COMPOUNDS
    Publication number: 20120071527
    Abstract: The invention provides compounds of formula I: wherein A, B, D, E, R1, R2, R3, R4, R5, X, and - - - have any values defined herein, as well as salts thereof. The compounds have activity as G-quadruplex DNA stabilizers and as anti-proliferative agents.
    Type: Application
    Filed: November 30, 2011
    Publication date: March 22, 2012
    Applicants: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY, RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Edmond J. Lavoie, Joseph E. Rice, Leroy F. Liu
  • THERAPEUTIC COMPOUNDS
    Publication number: 20120046234
    Abstract: The invention provides compounds of formula I, II, and III as defined herein, as well as salts thereof. The compounds may have activity as anti-proliferative agents.
    Type: Application
    Filed: August 1, 2008
    Publication date: February 23, 2012
    Inventors: Edmond J. LaVoie, Joseph E. Rice
  • Macrocyclic compounds which stabilize G-Quadruplex DNA and RNA
    Patent number: 8093235
    Abstract: The invention provides compounds of formula I: wherein A, B, D, E, R1, R2, R3, R4, R5, X, and ----- have any values defined herein, as well as salts thereof. The compounds have activity as G-quadruplex DNA stabilizers and as anti-proliferative agents.
    Type: Grant
    Filed: October 24, 2008
    Date of Patent: January 10, 2012
    Assignees: Rutgers, The State University of New Jersey, University of Medicine and Dentistry of New Jersey
    Inventors: Edmond J. Lavoie, Joseph E. Rice, Leroy F. Liu
  • THERAPEUTIC COMPOUNDS
    Publication number: 20110230531
    Abstract: The invention provides compounds of formula (I) wherein A, B, R1, F, G, n, n? and the dotted line have any values defined herein, as well as salts thereof. The compounds have activity as anti-proliferative agents.
    Type: Application
    Filed: August 1, 2008
    Publication date: September 22, 2011
    Inventors: Edmond J. LaVoie, Joseph E. Rice, Satyanarayana Mavurapu
  • THERAPEUTIC COMPOUNDS
    Publication number: 20090156627
    Abstract: The invention provides compounds of formula I: wherein A, B, D, E, R1, R2, R3, R4, R5, X, and ----- have any values defined herein, as well as salts thereof. The compounds have activity as G-quadruplex DNA stabilizers and as anti-proliferative agents.
    Type: Application
    Filed: October 24, 2008
    Publication date: June 18, 2009
    Inventors: Edmond J. Lavoie, Joseph E. Rice, Leroy F. Liu
  • High pressure synthesis of substituted tetrathiafulvalenes
    Patent number: 4600784
    Abstract: A process is disclosed for one-step preparation of substituted tetrathiafulvalenes by reaction of carbon disulfide with acetylenic compounds under pressures of at least about 1,000 atmospheres. Substituted tetrathiafulvalenes made by this process are particularly useful as precursors to very pure tetrathiafulvalene, a compound which can complex with tetracyano-p-quinodimethane to form a charge-transfer salt having very high electrical conductivity.
    Type: Grant
    Filed: December 27, 1985
    Date of Patent: July 15, 1986
    Assignee: Koppers Company, Inc.
    Inventors: Yoshiyuki Okamoto, Joseph E. Rice