Patents by Inventor Joseph Espinal

Joseph Espinal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thiazolidinedione compounds
    Patent number: 5506245
    Abstract: The compounds are 5-(4-substituted benzyl)thiazolidine-2,4-diones, enantiomers, diastereoisomers and pharmaceutically tolerable salts thereof, useful for treating conditions of insulin-resistance and/or non insulin-dependent diabetes.A compound disclosed is: .(R,S)-5-{4-[2-benzofuran-2-yl)carbonylamino)ethyl]benzyl}thiazolidine-2,4 -dione.
    Type: Grant
    Filed: January 19, 1995
    Date of Patent: April 9, 1996
    Assignee: ADIR et Compagnie
    Inventors: Gilbert Regnier, Yves Charton, Jacques Duhault, Joseph Espinal
  • Thazolidinedione compounds
    Patent number: 5478853
    Abstract: The compounds are 5-(4-substituted benzyl)thiazolidine-2,4-diones, enantiomers, diastereoisomers and pharmaceutically tolerable salts thereof, useful for treating conditions of insulin-resistance and/or non insulin-dependent diabetes.A compound disclosed is: 5-{4-[2-(2-methoxy-5-chlorobenzamido)ethyl]benzyl}thiazolidine-2,4-dione.
    Type: Grant
    Filed: January 20, 1995
    Date of Patent: December 26, 1995
    Assignee: Adir et Compagnie
    Inventors: Gilbert Regnier, Yves Charton, Jacques Duhault, Joseph Espinal
  • Naphthalene compounds
    Patent number: 5422365
    Abstract: A compound selected from those of formula (I): ##STR1## wherein: R.sub.1, R'.sub.1 and R.sub.2 are each selected, independently of the others, from hydrogen and an alkyl radical, the two R.sub.2 groups being in the cis position in relation to the rings,and R, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9, R.sub.10, R'a and R'b are as defined in the description,useful therapeutically in the regulation of the secretion of insulin.
    Type: Grant
    Filed: August 12, 1994
    Date of Patent: June 6, 1995
    Assignee: Adir et Compagnie
    Inventors: David Billington, Francoise Perron-Sierra, Isabelle Picard, Jacques Duhault, Joseph Espinal
  • Diacylglycerol nicotinates
    Patent number: 5385920
    Abstract: Compounds of formula (I): ##STR1## in which: R.sub.1 and R.sub.2, which are identical or different, represent a higher alkyl or higher alkenyl radical,R.sub.3 represents a pyridyl or pyrazinyl radical,their isomers and their addition salts with a pharmaceutically acceptable acid and medicaments for the reduction of plasma lipids containing the same.
    Type: Grant
    Filed: June 9, 1993
    Date of Patent: January 31, 1995
    Assignee: Adir et Compagnie
    Inventors: Alex Cordi, Jean-Michel Lacoste, Jacques Duhault, Joseph Espinal, Michelle Boulanger