Patents by Inventor Joseph F. Gallelli

Joseph F. Gallelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bisulfite stabilization of 5-azacytidine
    Patent number: 4405611
    Abstract: A bisulfite addition product of 5-azacytidine and method wherein bisulfite is added to the azacytidine molecule at the 5-6 protonated imine bond. It is significant and advantageous to maintain the compound in this pro-drug form. At a pH above 6 and including higher physiological pH in animals, the bisulfite form reverts to the parent compound, rendering it readily available for utilization in the body. This product is produced as the bisulfite addition product at preferably a pH of 2.5.
    Type: Grant
    Filed: December 18, 1981
    Date of Patent: September 20, 1983
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Dulal C. Chatterji, Joseph F. Gallelli
  • Ethiodized oil emulsion for intravenous hepatography
    Patent number: 4404182
    Abstract: The present invention is directed towards the examination of formulations and evaluations of ethiodized oil emulsions. It is also concerned with formulations of ethiodized oil emulsified with lecithin which show about 30-35% of oil particles in the range 2-3 microns. A dosage utilized for animals, such as rabbits and monkeys for this ethiodized emulsion is 0.1-0.5 ml/kg utilizing computerized tomography, with a preferred dosage of 0.2 ml/kg for computerized tomography, and a dosage of 2 ml/kg for conventional X-rays.
    Type: Grant
    Filed: January 8, 1980
    Date of Patent: September 13, 1983
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Michael Vermess, Dulal C. Chatterji, George J. Grimes, Jr., Joseph F. Gallelli