Patents by Inventor Joseph F. Gardocki

Joseph F. Gardocki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chlorosulfate and azidosulfate esters of tetrahydro-2H-pyran-2-yl-methanol
    Patent number: 4582916
    Abstract: Sulfamates of the following formula (I): ##STR1## wherein X is O or CH.sub.2 and R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are as herein defined have been found to exhibit anticonvulsant activity and are thus useful in the treatment of conditions such as epilepsy. Further, pharmaceutical compositions containing a compound of formula (I) as well as methods for their use and intermediates form part of the present invention.
    Type: Grant
    Filed: February 11, 1985
    Date of Patent: April 15, 1986
    Assignee: McNeilab, Inc.
    Inventors: Bruce E. Maryanoff, Joseph F. Gardocki
  • Anticonvulsant sulfamate derivatives
    Patent number: 4513006
    Abstract: Sulfamates of the following formula (I): ##STR1## wherein X is O or CH.sub.2 and R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are as herein defined have been found to exhibit anticonvulsant activity and are thus useful in the treatment of conditions such as epilepsy. Further, pharmaceutical compositions containing a compound of formula (I) as well as methods for their use and intermediates form part of the present invention.
    Type: Grant
    Filed: September 26, 1983
    Date of Patent: April 23, 1985
    Assignee: McNeil Lab., Inc.
    Inventors: Bruce E. Maryanoff, Joseph F. Gardocki
  • Analgesic potentiation
    Patent number: 4338324
    Abstract: The analgesic effect of zomepirac is potentiated by simultaneously or sequentially administering to a subject suffering from pain, butorphanol, in a nonanalgesic amount thereby significantly reducing the dosage of zomepirac.
    Type: Grant
    Filed: March 17, 1981
    Date of Patent: July 6, 1982
    Assignee: McNeilab, Inc.
    Inventor: Joseph F. Gardocki
  • Analgesic potentiation
    Patent number: 4242353
    Abstract: A method for producing analgesia by administering a 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-.alpha.-methylbenzeneacetic acid compound with acetaminophen, and compositions therefor.
    Type: Grant
    Filed: December 18, 1978
    Date of Patent: December 30, 1980
    Assignee: McNeilab, Inc.
    Inventor: Joseph F. Gardocki
  • Analgesic potentiation
    Patent number: 4234601
    Abstract: A method of producing analgesia by employing 2-[(2,6-dichlorophenyl)amino]-benzeneacetic acid or salt thereof together with acetaminophen and compositions therefor.
    Type: Grant
    Filed: December 18, 1978
    Date of Patent: November 18, 1980
    Assignee: McNeilab, Inc.
    Inventor: Joseph F. Gardocki
  • Analgesic potentiation
    Patent number: 4233316
    Abstract: A method for producing analgesia by administering a 6-methoxy-.alpha.-methyl-2-naphthaleneacetic acid compound with acetaminophen and compositions therefor.
    Type: Grant
    Filed: December 18, 1978
    Date of Patent: November 11, 1980
    Assignee: McNeilab, Inc.
    Inventor: Joseph F. Gardocki
  • Analgesic potentiation
    Patent number: 4233315
    Abstract: A method of producing analgesia by administering m-benzoylhydratropic acid or a salt thereof together with acetaminophen and compositions therefor.
    Type: Grant
    Filed: December 18, 1978
    Date of Patent: November 11, 1980
    Assignee: McNeilab, Inc.
    Inventor: Joseph F. Gardocki
  • Analgesic potentiation
    Patent number: 4233314
    Abstract: A method of producing analgesia by administering .alpha.-methyl-3-phenoxybenzeneacetic acid or salt thereof together with acetaminophen and compositions therefor.
    Type: Grant
    Filed: December 18, 1978
    Date of Patent: November 11, 1980
    Assignee: McNeilab, Inc.
    Inventor: Joseph F. Gardocki
  • Analgesic potentiation
    Patent number: 4233317
    Abstract: A method for producing analgesia by administering a 3-(4-biphenylylcarbonyl)propionic acid compound together with acetaminophen and compositions therefor.
    Type: Grant
    Filed: December 18, 1978
    Date of Patent: November 11, 1980
    Assignee: McNeilab, Inc.
    Inventor: Joseph F. Gardocki
  • Analgesic potentiation
    Patent number: 4233313
    Abstract: A method of producing analgesia by orally administering 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid or salt thereof.
    Type: Grant
    Filed: December 18, 1978
    Date of Patent: November 11, 1980
    Assignee: McNeilab, Inc.
    Inventor: Joseph F. Gardocki
  • Analgesic potentiation
    Patent number: 4207340
    Abstract: A method of producing analgesia by administering (Z)-5-fluoro-2-methyl-1-{[4-methylsulfinyl)-phenyl]methylene}-1H-indene-3- acetic acid or a salt thereof together with acetaminophen and compositions therefor.
    Type: Grant
    Filed: December 18, 1978
    Date of Patent: June 10, 1980
    Assignee: McNeilab, Inc.
    Inventor: Joseph F. Gardocki