Abstract: An ammonia slip catalyst (ASC) comprising a first SCR catalyst, an oxidation catalyst comprising ruthenium or a Ru mixture, such as a Pt and Ru mixture, on a support comprising a rutile phase and a substrate is described. In some configurations, the ASC comprises a second oxidation catalyst. In other configurations, the ASC comprises a second oxidation catalyst and a third oxidation catalyst. The ASC's are useful for selective catalytic reduction (SCR) of NOx in exhaust gases and in reducing the amount of ammonia slip. Methods for producing such articles are described. Methods of using the ammonia slip catalyst in an SCR process, where the amount of ammonia slip is reduced, are also described.