Abstract: The present disclosure relates generally to compounds and compositions, and their use as kinase inhibitors.

Abstract: The present application provides tricyclic urea compounds that modulate the activity of the V617F variant of JAK2, which are useful in the treatment of various diseases, including cancer.

Abstract: This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment may determine at least one of a downlink path loss value or an uplink path loss value associated with a base station; receive system information, a semi-persistently configured grant via RRC or a dynamic uplink grant via DCI from the base station, wherein the RRC signaling or the dynamic uplink grant identifies a power control value associated with one user or a plurality of users associated with the base station; and determine a transmit power for a data or control transmission based at least in part on at least one of the downlink path loss value or the uplink path loss value and the power control value. Numerous other aspects are provided.

Abstract: There is set forth herein a device comprising structure defining a detector surface configured for supporting biological or chemical substances, and a sensor array comprising light sensors and circuitry to transmit data signals using photons detected by the light sensors. The device can include one or more features for reducing fluorescence range noise in a detection band of the sensor array.

Abstract: A magnetic write design for reducing Wide Area Track Erasure (WATEr). The write head design includes a magnetic pole and a non-magnetic, electrically conductive eddy current confining structure (ECC structure) formed adjacent to the write pole at the air bearing surface (ABS). The design can be embodied in a longitudinal write head having a magnetic pole, such as a P2 pole pedestal, with a non-magnetic, electrically conductive material surrounding three sides of the pole. For further protection against WATEr, a first, or bottom pole (P1) can be constructed with a high permeability, high Bs material at the write gap, and a low permeability, low Bs material formed there under. Another layer of high permeability, high Bs material can optionally be provided beneath the low permeability low Bs material layer. The invention can also be embodied in a perpendicular write head having a write pole with a non-magnetic, electrically conductive material surrounding all or a portion of the write pole at the ABS.

Abstract: A magnetic write design for reducing Wide Area Track Erasure (WATEr). The write head design includes a magnetic pole and a non-magnetic, electrically conductive eddy current confining structure (ECC structure) formed adjacent to the write pole at the air bearing surface (ABS). The design can be embodied in a longitudinal write head having a magnetic pole, such as a P2 pole pedestal, with a non-magnetic, electrically conductive material surrounding three sides of the pole. For further protection against WATEr, a first, or bottom pole (P1) can be constructed with a high permeability, high Bs material at the write gap, and a low permeability, low Bs material formed there under. Another layer of high permeability, high Bs material can optionally be provided beneath the low permeability low Bs material layer. The invention can also be embodied in a perpendicular write head having a write pole with a non-magnetic, electrically conductive material surrounding all or a portion of the write pole at the ABS.

Abstract: A method for identifying victim tracks distanced from an aggressor track in a hard disk drive that are deleteriously affected by long range fringe effects causing adjacent track interference (ATI) when the aggressor track is written includes writing first and second frequencies to candidate victim tracks, and writing a third frequency to the aggressor track. The amplitudes of the remaining frequencies are read and output and if desired normalized as an indication of ATI to distant victim tracks. Or, data can be written and on-track error rates (OTER) used to determine ATI.