Abstract: Z maps combined with a standardized stimulus in the form of a targeted arterial partial pressures of carbon dioxide provide suprisingly enhanced images for the assessment of pathological CVR. For example, the z-map assessment of patients with known steno-occlusive diseases of the cervico-cerebral vasculature showed an enhanced resolution of the presence, localization, and severity of the pathological CVR. Z-map have been found to be useful to reduce the confounding effects of test-to-test, subject-to-subject, and platform-to-platform variability for comparison of CVR images showing the importance of combining this analysis with the standardized stimulus.

Abstract: Data account management systems and methods are described. A server is in communication with one or more information source systems, at least one user device associated with at least one user and one or more electronic data accounts associated with the user. The server links the electronic data accounts, monitors data among the information source systems and the linked accounts for any changes in activity associated with the user, predicts a behavioral activity of the user via machine learning based on at least one of the monitored data and historical data associated with the user, identifies at least one notification instruction specific to the user based on the predicted behavioral activity, and generates an interactive graphical user interface (GUI) for display on the user device. The interactive GUI presents one or more of the notification instruction and a user profile of the at least one user among the linked accounts.

Abstract: A proppant container facilitates the transportation of wet sand for use in a hydraulic fracturing operation. The container is mounted in a cradle that tips downward in arcuate motion for discharge or proppant through a top opening The tipping mechanism may be driven by a system of gears or a hydraulic ram.

Abstract: Systems and methods for resolving discrepancies between recordings made by multiple scorekeepers for a game comprising discrete events. In an example, a discrepancy resolving system include at least two personal computing devices and a remote server connected thereto, wherein each of the personal computing devices and the server is equipped with software which enables the personal computing devices to receive recordings of game events from a different scorekeeper, sending such recordings to the server, where the recordings from different scorekeepers are compared and discrepancies detected. The discrepancies are sent back to the computing devices for further responses from the scorekeepers. When the responses from different scorekeepers agree with each other, the discrepancies are resolved.

Abstract: Z maps combined with a standardized stimulus in the form of a targeted arterial partial pressures of carbon dioxide provide surprisingly enhanced images for the assessment of pathological CVR. For example, the z-map assessment of patients with known steno-occlusive diseases of the cervico-cerebral vasculature showed an enhanced resolution of the presence, localization, and severity of the pathological CVR. Z-map have been found to be useful to reduce the confounding effects of test-to-test, subject-to-subject, and platform-to-platform variability for comparison of CVR images showing the importance of combining this analysis with the standardized stimulus.

Abstract: A respiratory gas delivery system monitors gas flow over the course of a breath in real time and uses this parameter to simulate, in whole or part, the function of a reference respiratory gas delivery system, in particular structural features, particularly structural components of parts of the reference system, to overcome a structural limitation of the reference system.

Abstract: The disclosure provides compounds useful as adjuvants in vaccines, as well as methods of synthesizing such compounds and methods of using such compounds in the formulation of a vaccine. The disclosure also features methods of administering such vaccines to a subject (e.g., a mammalian subject, such as a human) in order to treat or prevent one or more diseases, such as a disease caused by a viral or bacterial infection.

Abstract: A method and device for reducing the damaging effects of a blast or concussive event includes applying pressure to at least one jugular vein to reduce the egress of blood from the cranial cavity during the incidence of the concussive event. Reducing blood out flow from the cranial cavity increases intracranial pressure of the cerebrospinal fluid to reduce the risk of traumatic brain injury and injuries to the spinal column. Reducing blood out flow further increases the intracranial pressure, and thereby increases the pressure of the cochlear fluid, the vitreous humor and the cerebrospinal fluid to thereby reduce the risk of injury to the inner ear, internal structure of the eye and of the spinal column. In addition, increasing intracranial pressure reduces the likelihood of brain injury and any associated loss of olfactory function.

Abstract: A method and device for reducing the damaging effects of a blast or concussive event includes applying pressure to at least one jugular vein to reduce the egress of blood from the cranial cavity during the incidence of the concussive event. Reducing blood out flow from the cranial cavity increases intracranial pressure of the cerebrospinal fluid to reduce the risk of traumatic brain injury and injuries to the spinal column. Reducing blood out flow further increases the intracranial pressure, and thereby increases the pressure of the cochlear fluid, the vitreous humor and the cerebrospinal fluid to thereby reduce the risk of injury to the inner ear, internal structure of the eye and of the spinal column. In addition, increasing intracranial pressure reduces the likelihood of brain injury and any associated loss of olfactory function.

Abstract: A pre-insulated flexible hot water pipe comprising a flexible pipe core; a flexible insulator surrounding the flexible pipe core; and a coating surrounding the flexible insulator.

Abstract: Systems and methods for resolving discrepancies between recordings made by multiple scorekeepers for a game comprising discrete events. In an example, a discrepancy resolving system include at least two personal computing devices and a remote server connected thereto, wherein each of the personal computing devices and the server is equipped with software which enables the personal computing devices to receive recordings of game events from a different scorekeeper, sending such recordings to the server, where the recordings from different scorekeepers are compared and discrepancies detected. The discrepancies are sent back to the computing devices for further responses from the scorekeepers. When the responses from different scorekeepers agree with each other, the discrepancies are resolved.

Abstract: A method of controlling a gas delivery apparatus including an apparatus controllable variable using an iterative algorithm to deliver a test gas (TG) for non-invasively determining a subject's pulmonary blood flow comprising iteratively generating and evaluating test values of a iterated variable based on an iterative algorithm in order output a test value of the iterated variable that meets a test criterion wherein iterative algorithm is characterized in that it defines a test mathematical relationship between the at least one apparatus controllable variable, the iterated variable and an end tidal concentration of test gas attained by setting the apparatus controllable variable, such that the iterative algorithm is determinative of whether iteration on the test value satisfies a test criterion or iteratively generates a progressively refined test value.

Abstract: Systems and methods for resolving discrepancies between recordings made by multiple scorekeepers for a game comprising discrete events. In an example, a discrepancy resolving system include at least two personal computing devices and a remote server connected thereto, wherein each of the personal computing devices and the server is equipped with software which enables the personal computing devices to receive recordings of game events from a different scorekeeper, sending such recordings to the server, where the recordings from different scorekeepers are compared and discrepancies detected. The discrepancies are sent back to the computing devices for further responses from the scorekeepers. When the responses from different scorekeepers agree with each other, the discrepancies are resolved.

Abstract: A method for continuously processing at least two liquid feed streams is provided. A system for continuously processing at least two liquid feed streams is also provided.

Abstract: An apparatus and method for controlling the end tidal partial pressure of a gas X in a subject's lung, and to the use of such an apparatus and method for research, diagnostic and therapeutic purposes, wherein the method consists of: -obtaining input of a series of logistically attainable PetX values for a series of respective breaths: -determining an amount of gas X required to be inspired by the subject in an inspired gas to target the PetX for each of said respective breaths; and controlling a gas delivery device to deliver the amount of gas in a volume of gas delivered to the subject in each of said respective breaths to target the respective PetX for that breath.

Abstract: A method and device for reducing the damaging effects of a blast or concussive event includes applying pressure to at least one jugular vein to reduce the egress of blood from the cranial cavity during the incidence of the concussive event. Reducing blood out flow from the cranial cavity increases intracranial pressure of the cerebrospinal fluid to reduce the risk of traumatic brain injury and injuries to the spinal column. Reducing blood out flow further increases the intracranial pressure, and thereby increases the pressure of the cochlear fluid, the vitreous humor and the cerebrospinal fluid to thereby reduce the risk of injury to the inner ear, internal structure of the eye and of the spinal column. In addition, increasing intracranial pressure reduces the likelihood of brain injury and any associated loss of olfactory function.

Abstract: A method for continuously processing at least two liquid feed streams is provided. A system for continuously processing at least two liquid feed streams is also provided.

Abstract: Implementations described and claimed herein provide an underwater vehicle includes a vehicle body having a frame enclosed by a fairing. The vehicle body extends between a proximal end and a distal end and defining an interior. A nose is disposed at the proximal end of the vehicle body. The nose has a tow system configured to move between a tow position and a stow position. A propulsion system is disposed at the distal end of the vehicle body. The propulsion system includes a plurality of control fins and a thruster. A power distribution system is housed in the interior of the vehicle body. The power distribution system includes a first power system housed in a first pressure vessel and a second power system housed in a second pressure vessel. The first pressure vessel is isolated from the second pressure vessel.

Abstract: A method of identifying alveolar ventilation (VA) in a subject, the method comprising: (1) using a breathing circuit which, at exhalation, keeps exhaled gas separate from inhaled gas and at inhalation, when a first gas set (FGS) flow is less than the subject's minute ventilation (VE), results in a subject inhaling FGS first and then a second gas set (SGS), for the balance of inhalation; (2) setting the FGS flow at a rate greater that VE; (3) measuring an end tidal CO2 concentration at a steady state; (4) progressively lowering the FGS flow until a time equal to a recirculation time of CO2 in the subject; and (5) deriving VA as the rate of FGS flow at the intersection between an average PETCO2 in a steady state and a line fit to the PETCO2 values after the rise in PETCO2 values begins until the recirculation time.

Abstract: A pre-insulated flexible hot water pipe comprising a flexible pipe core; a flexible insulator surrounding the flexible pipe core; and a coating surrounding the flexible insulator.