Patents by Inventor Joseph Fortunak

Joseph Fortunak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF COPPER DISORDERS
    Publication number: 20250114312
    Abstract: The present disclosure relates to compositions comprising fixed doses of triethylenetetramine disuccinate, and methods for their use in the prophylaxis and treatment of copper-related diseases, disorders and conditions.
    Type: Application
    Filed: August 9, 2024
    Publication date: April 10, 2025
    Inventors: Joseph FORTUNAK, Garth COOPER, Margaret COOPER
  • METHOD FOR TRIETHYLENETETRAMINE PURIFICATION
    Publication number: 20240043370
    Abstract: Methods for the purification of impure triethylenetetramine into highly pure triethylenetetramine are described. In particular, methods for the preparation of relatively pure salts of triethylenetetramine starting from crude triethylenetetramine and crude salts of trethylenetetramine are described.
    Type: Application
    Filed: August 7, 2023
    Publication date: February 8, 2024
    Inventor: Joseph FORTUNAK
  • PREVENTION AND TREATMENT OF CORONAVIRUS AND RELATED RESPIRATORY INFECTIONS
    Publication number: 20220280450
    Abstract: The present disclosure relates to compositions comprising copper-depriving compounds, including copper chelators, useful for the prophylaxis and treatment of SARS-CoV-2, SARS-CoV-2 variants and mutations, and other coronavirus infections.
    Type: Application
    Filed: March 4, 2022
    Publication date: September 8, 2022
    Inventors: Joseph FORTUNAK, Garth COOPER, Margaret COOPER
  • TREATMENT OF COPPER DISORDER
    Publication number: 20220280451
    Abstract: The present disclosure relates to compositions comprising fixed doses of triethylenetetramine disuccinate, and methods for their use in the prophylaxis and treatment of copper-related diseases, disorders and conditions.
    Type: Application
    Filed: March 4, 2022
    Publication date: September 8, 2022
    Inventors: Joseph FORTUNAK, Garth COOPER, Margaret COOPER
  • Intermediates useful in camptothecin synthesis
    Patent number: 5700939
    Abstract: The present invention provides a process for the asymmetric synthesis of camptothecin analogues as well as novel chemical intermediates of Formula I, II, and III. In general, the present process comprises conversion of a cis dioxolanone, having the same desired absolute configuration as the desired camptothecin analogue, to a compound of Formula I, II, or III, which compound is then converted to the desired camptothecin analogue.
    Type: Grant
    Filed: May 31, 1996
    Date of Patent: December 23, 1997
    Assignee: SmithKline Beecham Corporation
    Inventor: Joseph Fortunak
  • Intermediates prepared in an asymmetric total synthesis of camptothecin analogs
    Patent number: 5541329
    Abstract: The present invention provides a process for the asymmetric synthesis of camptothecin analogues as well as novel chemical intermediates of Formula I, II, and III. In general, the present process comprises conversion of a cis dioxolanone, having the same desired absolute configuration as the desired camptothecin analogue, to a compound of Formula I, II, or III, which compound is then converted to the desired camptothecin analogue.
    Type: Grant
    Filed: December 23, 1994
    Date of Patent: July 30, 1996
    Assignee: SmithKline Beecham Corporation
    Inventor: Joseph Fortunak
  • Process for asymmetric total synthesis of camptothecin analogues
    Patent number: 5468859
    Abstract: The present invention provides a process for the asymmetric synthesis of camptothecin analogs as well as novel chemical intermediates of Formula I, II, and III. In general, the present process comprises conversion of a cis dioxolanone, having the same desired absolute configuration as the desired camptothecin analog, to a compound of Formula I, II, or III, which compound is then converted to the desired camptothecin analog.
    Type: Grant
    Filed: December 23, 1994
    Date of Patent: November 21, 1995
    Assignee: SmithKline Beecham Corporation
    Inventors: Joseph Fortunak, John Kitteringham, Nicholas Sisti, Jeffery Wood
  • Process for asymmetric total synthesis of camptothecin analogues
    Patent number: 5405963
    Abstract: The present invention provides a process for the asymmetric synthesis of camptothecin analogues as well as novel chemical intermediates of Formula I, II, and III. In general, the present process comprises conversion of a cis dioxolanone, having the same desired absolute configuration as the desired camptothecin analogue, to a compound of Formula I, II, or III, which compound is then converted to the desired camptothecin analogue.
    Type: Grant
    Filed: June 10, 1993
    Date of Patent: April 11, 1995
    Assignee: SmithKline Beecham Corporation
    Inventors: Joseph Fortunak, John Kitteringham, Nicholas Sisti, Jeffery Wood