Patents by Inventor Joseph Gardecki
Joseph Gardecki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240131267Abstract: An injection apparatus, including: a needle configured to be inserted into a tissue; a light source to deliver light to the tissue to generate reflected light; a detector to detect the reflected light from the tissue; a processor coupled to the detector and configured to: analyze the reflected light from the tissue to identify a tissue type associated with the reflected light, and provide an output to a user based on the identified tissue type.Type: ApplicationFiled: February 25, 2022Publication date: April 25, 2024Inventors: Molly Wanner, William Farinelli, Richard Rox Anderson, Joseph A. Gardecki, Matthew J. Beatty, Guillermo J. Tearney
-
Publication number: 20240074643Abstract: In some embodiments, devices, systems, and methods for advancing and positioning tethered capsule microendoscopes are provided. In some embodiments, a device for capsule endomicroscopy is provided, comprising: a tether having a proximal end and distal end; an optical fiber disposed within the tether; a tube enclosing at least a portion of the tether, the tube having a proximal end and a distal end, a diameter of the tube being larger than the diameter of the tether; a housing coupled to the distal end of the tether and the distal end of the tube; and an optical element disposed within the housing, the optical element being optically coupled to the distal end of the optical fiber and configured to direct light received from the optical fiber toward a periphery of the housing.Type: ApplicationFiled: September 22, 2023Publication date: March 7, 2024Inventors: Guillermo J. Tearney, Chulho Daryl Hyun, Joseph A. Gardecki
-
Patent number: 11890077Abstract: Exemplary method and apparatus for diagnosing or characterizing an inflammation within an anatomical structure can be provided. For example, using at least one source arrangement, it is possible to provide at least one first electro-magnetic radiation to the anatomical structure at at least one first wavelength in vivo. With at least one detector arrangement, it is possible to detect at least one second electro-magnetic radiation at at least one second wavelength provided from the anatomical structure. The second radiation can be associated with the first radiation, and the first wavelength can be shorter than the second wavelength. The second radiation can be provided from the anatomical structure due to at least one change in the anatomical structure caused by the inflammation without providing an artificial fluorescence substance.Type: GrantFiled: January 28, 2021Date of Patent: February 6, 2024Assignee: The General Hospital CorporationInventors: Hao Wang, Joseph A. Gardecki, Guillermo J. Tearney
-
Publication number: 20240032855Abstract: An apparatus for determining a shape of a luminal sample including: a catheter including a lens, the catheter disposed within a strain-sensing sheath such that the lens rotates and translates; a structural imaging system optically coupled to the catheter; a strain-sensing system optically coupled to the catheter; and a controller coupled to the strain-sensing system and the structural imaging system. The controller determines: a first position of the catheter relative to the luminal sample at a first location within the strain-sensing sheath; a second position of the catheter relative to the luminal sample at a second location within the strain-sensing sheath; a first strain of the strain-sensing sheath at the first location; a second strain of the strain-sensing sheath at the second location; a local curvature of the luminal sample relative to the catheter; a local curvature of the catheter; and a local curvature of the luminal sample.Type: ApplicationFiled: October 10, 2023Publication date: February 1, 2024Applicant: The General Hospital CorporationInventors: Guillermo J. Tearney, Joseph A. Gardecki, Kanwarpal Singh
-
Patent number: 11864743Abstract: Apparatus and method can be provided for obtaining at least one anatomical sample. For example, it is possible to provide and insert a housing into a body or provided on a hydrated anatomical structure. Further, with a source, it is possible to emit an electromagnetic radiation which causes at least the anatomical sample(s) to attach to at least one portion of the housing. A compound can be provided on a surface of the housing, and the source provides the radiation to the compound and changes properties thereof to be adhesive. The source can provide the radiation to the housing, and can change properties of a surface thereof to be adhesive. A component can be provided on a surface of the anatomical structure, and the source provides the radiation to the compound and changes properties thereof to be adhesive.Type: GrantFiled: February 5, 2021Date of Patent: January 9, 2024Assignee: The General Hospital CorporationInventors: Guillermo J. Tearney, Joseph Gardecki, Chia-Pin Liang
-
Patent number: 11813068Abstract: An apparatus for determining a shape of a luminal sample including: a catheter including a lens, the catheter disposed within a strain-sensing sheath such that the lens rotates and translates; a structural imaging system optically coupled to the catheter; a strain-sensing system optically coupled to the catheter; and a controller coupled to the strain-sensing system and the structural imaging system. The controller determines: a first position of the catheter relative to the luminal sample at a first location within the strain-sensing sheath; a second position of the catheter relative to the luminal sample at a second location within the strain-sensing sheath; a first strain of the strain-sensing sheath at the first location; a second strain of the strain-sensing sheath at the second location; a local curvature of the luminal sample relative to the catheter; a local curvature of the catheter; and a local curvature of the luminal sample.Type: GrantFiled: June 24, 2022Date of Patent: November 14, 2023Assignee: The General Hospital CorporationInventors: Guillermo J. Tearney, Joseph A. Gardecki, Kanwarpal Singh
-
Patent number: 11793396Abstract: In some embodiments, devices, systems, and methods for advancing and positioning tethered capsule microendoscopes are provided. In some embodiments, a device for capsule endomicroscopy is provided, comprising: a tether having a proximal end and distal end; an optical fiber disposed within the tether; a tube enclosing at least a portion of the tether, the tube having a proximal end and a distal end, a diameter of the tube being larger than the diameter of the tether; a housing coupled to the distal end of the tether and the distal end of the tube; and an optical element disposed within the housing, the optical element being optically coupled to the distal end of the optical fiber and configured to direct light received from the optical fiber toward a periphery of the housing.Type: GrantFiled: January 11, 2019Date of Patent: October 24, 2023Assignee: The General Hospital CorporationInventors: Guillermo J. Tearney, Chulho Daryl Hyun, Joseph A. Gardecki
-
Publication number: 20230238135Abstract: A computer-implemented method for diagnosing a medical condition of a patient is provided. The method can include causing, using one or more processors, an excitation source to emit an excitation light towards a region of interest of an artery, receiving, using the one or more processors and a detector, imaging data of the region of interest of the artery, generating, using the one or more processors and the imaging data, an image of the region of interest, determining, using the one or more processors, a risk region of an atheromatous plaque, based on the imaging data, and determining, using the one or more processors, that the patient has a severe case of an atheromatous plaque, based on the determined risk region of the atheromatous plaque.Type: ApplicationFiled: June 21, 2021Publication date: July 27, 2023Applicant: The General Hospital CorporationInventors: Farouc Amin Jaffer, Guillermo Tearney, Joseph Gardecki, Mazen Albaghdadi, Ryutaro Ikegami, Mohamad Kassab
-
Patent number: 11633104Abstract: Exemplary embodiments of systems and methods can be provided which can generate data associated with at least one portion of a sample. For example, at least one first radiation can be forwarded to the portion through at least one optical arrangement. At least one second radiation can be received from the portion which is based on the first radiation. Based on an interaction between the optical arrangement and the first radiation and/or the second radiation, the optical arrangement can have a first transfer function. Further, it is possible to forward at least one third radiation to the portion through such optical arrangement (or through another optical arrangement), and receive at least one fourth radiation from the portion which is based on the third radiation. Based on an interaction between the optical arrangement (or the other optical arrangement) and the third radiation and/or the fourth radiation, the optical arrangement (or the other optical arrangement) can have a second transfer function.Type: GrantFiled: September 20, 2019Date of Patent: April 25, 2023Assignee: The General Hospital CorporationInventors: Guillermo J. Tearney, Brett Eugene Bouma, Joseph A. Gardecki, Linbo Liu
-
Patent number: 11553841Abstract: Exemplary systems, devices, methods, apparatus and computer-accessible media for providing and/or utilizing optical frequency domain imaging (OFDI) and fluorescence of structures and, e.g., multimodality imaging using OFDI techniques and fluorescence imaging techniques are described. For example, an arrangement can provide at least one electro-magnetic radiation to an anatomical structure. Such exemplary arrangement can include at least one optical core and at least one cladding at least partially surrounding the fiber(s). A region between the optical core(s) and the cladding(s) can have an index that is different from indexes of the optical core(s) and the cladding(s). The arrangement can also include at least one apparatus which is configured to transmit the radiation(s) via the optical core(s) and the cladding(s) to the anatomical structure.Type: GrantFiled: March 3, 2021Date of Patent: January 17, 2023Assignee: The General Hospital CorporationInventors: Guillermo J. Tearney, Brett Eugene Bouma, Hongki Yoo, Milen Shishkov, Joseph Gardecki, Roman Shubochkin, Theodore Morse, Farouc Amin Jaffer
-
Publication number: 20220330881Abstract: An apparatus for determining a shape of a luminal sample including: a catheter including a lens, the catheter disposed within a strain-sensing sheath such that the lens rotates and translates; a structural imaging system optically coupled to the catheter; a strain-sensing system optically coupled to the catheter; and a controller coupled to the strain-sensing system and the structural imaging system. The controller determines: a first position of the catheter relative to the luminal sample at a first location within the strain-sensing sheath; a second position of the catheter relative to the luminal sample at a second location within the strain-sensing sheath; a first strain of the strain-sensing sheath at the first location; a second strain of the strain-sensing sheath at the second location; a local curvature of the luminal sample relative to the catheter; a local curvature of the catheter; and a local curvature of the luminal sample.Type: ApplicationFiled: June 24, 2022Publication date: October 20, 2022Applicant: The General Hospital CorporationInventors: Guillermo J. Tearney, Joseph A. Gardecki, Kanwarpal Singh
-
Patent number: 11406318Abstract: An apparatus for determining a shape of a luminal sample including: a catheter including a lens, the catheter disposed within a strain-sensing sheath such that the lens rotates and translates; a structural imaging system optically coupled to the catheter; a strain-sensing system optically coupled to the catheter; and a controller coupled to the strain-sensing system and the structural imaging system. The controller determines: a first position of the catheter relative to the luminal sample at a first location within the strain-sensing sheath; a second position of the catheter relative to the luminal sample at a second location within the strain-sensing sheath; a first strain of the strain-sensing sheath at the first location; a second strain of the strain-sensing sheath at the second location; a local curvature of the luminal sample relative to the catheter; a local curvature of the catheter; and a local curvature of the luminal sample.Type: GrantFiled: March 23, 2018Date of Patent: August 9, 2022Assignee: The General Hospital CorporationInventors: Guillermo J. Tearney, Joseph A. Gardecki, Kanwarpal Singh
-
Publication number: 20210401414Abstract: Apparatus and method can be provided for obtaining at least one anatomical sample. For example, it is possible to provide and insert a housing into a body or provided on a hydrated anatomical structure. Further, with a source, it is possible to emit an electromagnetic radiation which causes at least the anatomical sample(s) to attach to at least one portion of the housing. A compound can be provided on a surface of the housing, and the source provides the radiation to the compound and changes properties thereof to be adhesive. The source can provide the radiation to the housing, and can change properties of a surface thereof to be adhesive. A component can be provided on a surface of the anatomical structure, and the source provides the radiation to the compound and changes properties thereof to be adhesive.Type: ApplicationFiled: February 5, 2021Publication date: December 30, 2021Inventors: Guillermo J. Tearney, Joseph Gardecki, Chia-Pin Liang
-
Publication number: 20210267460Abstract: Exemplary systems, devices, methods, apparatus and computer-accessible media for providing and/or utilizing optical frequency domain imaging (OFDI) and fluorescence of structures and, e.g., multimodality imaging using OFDI techniques and fluorescence imaging techniques are described. For example, an arrangement can provide at least one electro-magnetic radiation to an anatomical structure. Such exemplary arrangement can include at least one optical core and at least one cladding at least partially surrounding the fiber(s). A region between the optical core(s) and the cladding(s) can have an index that is different from indexes of the optical core(s) and the cladding(s). The arrangement can also include at least one apparatus which is configured to transmit the radiation(s) via the optical core(s) and the cladding(s) to the anatomical structure.Type: ApplicationFiled: March 3, 2021Publication date: September 2, 2021Inventors: Guillermo J. Tearney, Brett Eugene Bouma, Hongki Yoo, Milen Shishkov, Joseph Gardecki, Roman Shubochkin, Theodore Morse, Farouc Amin Jaffer
-
Publication number: 20210177265Abstract: Probes, catheters, systems, methods, and ferrofluids are provides for acquiring direct visualization medical images of internal structures. The probes can include a channel, an optical waveguide, and a ferrofluid attractor. The ferrofluid attractor can be configured to magnetically attract the ferrofluid when exiting a distal port of the channel The medical image can be acquired through the ferrofluid, which is excluding blood from the area that the ferrofluid is occupying. The ferrofluid has a lower optical absorbance than blood, so the acquiring the image through the ferrofluid rather than through blood provides improved images.Type: ApplicationFiled: October 25, 2018Publication date: June 17, 2021Inventors: Serguei Melnitochouk, Guillermo J. Tearney, Grace E. Baldwin, Joseph A. Gardecki
-
Publication number: 20210161387Abstract: Exemplary method and apparatus for diagnosing or characterizing an inflammation within an anatomical structure can be provided. For example, using at least one source arrangement, it is possible to provide at least one first electro-magnetic radiation to the anatomical structure at at least one first wavelength in vivo. With at least one detector arrangement, it is possible to detect at least one second electro-magnetic radiation at at least one second wavelength provided from the anatomical structure. The second radiation can be associated with the first radiation, and the first wavelength can be shorter than the second wavelength. The second radiation can be provided from the anatomical structure due to at least one change in the anatomical structure caused by the inflammation without providing an artificial fluorescence substance.Type: ApplicationFiled: January 28, 2021Publication date: June 3, 2021Inventors: Hao Wang, Joseph A. Gardecki, Guillermo J. Tearney
-
Patent number: 10959712Abstract: Apparatus and method can be provided for obtaining at least one anatomical sample. For example, it is possible to provide and insert a housing into a body or provided on a hydrated anatomical structure. Further, with a source, it is possible to emit an electromagnetic radiation which causes at least the anatomical sample(s) to attach to at least one portion of the housing. A compound can be provided on a surface of the housing, and the source provides the radiation to the compound and changes properties thereof to be adhesive. The source can provide the radiation to the housing, and can change properties of a surface thereof to be adhesive. A component can be provided on a surface of the anatomical structure, and the source provides the radiation to the compound and changes properties thereof to be adhesive.Type: GrantFiled: March 10, 2016Date of Patent: March 30, 2021Assignee: The General Hospital CorporationInventors: Guillermo J. Tearney, Joseph Gardecki, Chia-Pin Liang
-
Patent number: 10939825Abstract: Exemplary systems, devices, methods, apparatus and computer-accessible media for providing and/or utilizing optical frequency domain imaging (OFDI) and fluorescence of structures and, e.g., multimodality imaging using OFDI techniques and fluorescence imaging techniques are described. For example, an arrangement can provide at least one electro-magnetic radiation to an anatomical structure. Such exemplary arrangement can include at least one optical core and at least one cladding at least partially surrounding the fiber(s). A region between the optical core(s) and the cladding(s) can have an index that is different from indexes of the optical core(s) and the cladding(s). The arrangement can also include at least one apparatus which is configured to transmit the radiation(s) via the optical core(s) and the cladding(s) to the anatomical structure.Type: GrantFiled: November 22, 2016Date of Patent: March 9, 2021Assignees: The General Hospital Corporation, Trustees of Boston UniversityInventors: Guillermo J. Tearney, Brett Eugene Bouma, Hongki Yoo, Milen Shishkov, Joseph Gardecki, Roman Shubochkin, Theodore Morse, Farouc Amin Jaffer
-
Patent number: 10912462Abstract: Exemplary method and apparatus for diagnosing or characterizing an inflammation within an anatomical structure can be provided. For example, using at least one source arrangement, it is possible to provide at least one first electro-magnetic radiation to the anatomical structure at least one first wavelength in vivo. With at least one detector arrangement, it is possible to detect at least one second electro-magnetic radiation at least one second wavelength provided from the anatomical structure. The second radiation can be associated with the first radiation, and the first wavelength can be shorter than the second wavelength. The second radiation can be provided from the anatomical structure due to at least one change in the anatomical structure caused by the inflammation without providing an artificial fluorescence substance.Type: GrantFiled: July 27, 2015Date of Patent: February 9, 2021Assignee: The General Hospital CorporationInventors: Hao Wang, Joseph A. Gardecki, Guillermo J. Tearney
-
Patent number: 10893806Abstract: An apparatus according to an exemplary embodiment of the present disclosure can include a first section(s) and a second section(s) which can have a cross-section that can be smaller than that of the first section. The first and second sections can be a particular section and can include memory-forming characteristics. An imaging arrangement can be in communication with the first section or the second section. The particular section can have a first shape when the particular section can be constrained, and the particular section can have a second shape when the particular section can be unconstrained. The second shape can be more curved than the first shape.Type: GrantFiled: January 29, 2014Date of Patent: January 19, 2021Assignee: The General Hospital CorporationInventors: Guillermo J. Tearney, William C. Warger, II, Joseph Gardecki, Jose L. Guerrero, Farouc Jaffer, Kevin Gallagher