Patents by Inventor Joseph Gerace Rico

Joseph Gerace Rico has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INDAZOLE DERIVATIVES
    Publication number: 20110028447
    Abstract: This invention relates to compounds, pharmaceutical compositions and methods for the treatment of a condition mediated by CB1 receptor activity in a mammalian subject including a human, which comprises administering to a mammal in need of such treatment a therapeutically effective amount of the compound of formula (I) wherein R1, R2 and R3 are as defined in this specification.
    Type: Application
    Filed: February 26, 2009
    Publication date: February 3, 2011
    Inventors: Ingrid Price Buchler, Michael Joseph Hayes, Shridhar Gajanan Hegde, Susan Landis Hockerman, Darin Eugene Jones, Steven Wade Kortum, Joseph Gerace Rico, Ruth Elizabeth TenBrink, Kun Ken Wu
  • Pyrimidine compounds and derivatives thereof
    Patent number: 6831199
    Abstract: The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, wherein A is pharmaceutical compositions thereof and methods of using such compounds and compositions as &agr;v&bgr;3 antagonists.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: December 14, 2004
    Assignee: G. D. Searle & Co.
    Inventors: Peter Gerrard Ruminski, Michael Clare, Paul Waddell Collins, Bipinchandra Nanubhai Desai, Richard John Lindmark, Joseph Gerace Rico, Thomas Edward Rogers, Mark Andrew Russell
  • Heterocyclic glycyl beta-alanine derivatives
    Publication number: 20040127477
    Abstract: The present invention relates to a class of compounds represented by the Formula I 1
    Type: Application
    Filed: November 20, 2003
    Publication date: July 1, 2004
    Applicant: G. D. Searle & Co.
    Inventors: Nizal Samuel Chandrakumar, Bipinchandra Nanubhai Desai, Balekudru Devadas, Alan Frank Gasiecki, Renee Huff, Ish K. Khanna, James W. Malecha, Julie M. Miyashiro, Shashidhar N. Rao, Joseph Gerace Rico, Thomas Edward Rogers, Peter Gerrard Ruminski, Mark Andrew Russell, Yi Yu
  • Aromatic sulfone hydroxamic acid metalloprotease inhibitor
    Publication number: 20040048852
    Abstract: A treatment process is disclosed that comprises administering an effective amount of an aromatic sulfone hydroxamic acid that exhibits excellent inhibitory activity of one or more matrix metalloprotease (MMP) enzymes, such as MMP-2, MMP-9, and MMP-13, while exhibiting substantially less inhibition at least of MMP-1 to a host having a condition associated with pathological matrix metalloprotease activity. The administered enzyme inhibitor corresponds in structure to formula (I), below, or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are both hydrido or R1 and R2 together with the atoms to which they are bonded form a 5- to 8-membered ring containing one, two, or three heteroatoms in the ring that are oxygen, sulfur, or nitrogen. R3 in formula (I) is an optionally substituted aryl or optionally substituted heteroaryl radical.
    Type: Application
    Filed: January 7, 2003
    Publication date: March 11, 2004
    Inventors: Thomas E. Barta, Daniel P. Becker, Terri L. Boehm, Gary A. DeCrezcenzo, John N. Freskos, Daniel P. Getman, Joseph J. McDonald, Clara I. Villamil, Louis John Bedell, Jeffery N. Carroll, Theresa R. Fletcher, Susan Landis Hockerman, Stephen A. Kolodziej, Madeleine H. Li, Deborah A. Mischke, Patrick B. Mullins, Carol Pearcy Howard, Joseph Gerace Rico, Nathan W. Stehle
  • Heterocyclic glycyl &bgr;-alanine derivatives
    Patent number: 6689754
    Abstract: The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salts thereof, pharmaceutical compositions containing such compounds and methods of treating conditions mediated by the &agr;v&bgr;3 integrin.
    Type: Grant
    Filed: April 8, 1999
    Date of Patent: February 10, 2004
    Assignee: G. D. Searle & Co.
    Inventors: Nizal Samuel Chandrakumar, Bipinchandra Nanubhai Desai, Balekudru Devadas, Alan Frank Gasiecki, Renee Huff, Ish K. Khanna, James W. Malecha, Julie M. Miyashiro, Shashidhar N. Rao, Joseph Gerace Rico, Thomas Edward Rogers, Peter Gerrard Ruminski, Mark Andrew Russell, Yi Yu
  • Amino benzenepropanoic acid compounds and derivatives thereof
    Patent number: 6100423
    Abstract: The present invention is directed to compounds of the formula ##STR1## where R.sup.1 is BOC or H, R is H or lower alkyl; X and Y are the same or different halo atoms selected from the group consisting of Cl, Br or I and pharmaceutically acceptable salts and isomers thereof.
    Type: Grant
    Filed: March 3, 1999
    Date of Patent: August 8, 2000
    Assignee: G. D. Searle & Co.
    Inventors: Joe T. Collins, Balekudru Devadas, Hwang-fun Lu, James W. Malecha, Julie Marion Miyashiro, Srinivasan Nagarajan, Joseph Gerace Rico, Thomas E. Rogers
  • Aminobenzamidinosuccinyl lactone derivatives useful as inhibitors of platelet aggregation
    Patent number: 6037365
    Abstract: This invention provides a compound of the formula ##STR1## or a pharmaceutically acceptable salt thereof. The invention also provides pharmaceutical compositions of such compounds and a method of treatment to inhibit aggregation of platelets.
    Type: Grant
    Filed: September 25, 1998
    Date of Patent: March 14, 2000
    Assignee: G.D. Searle & Co.
    Inventors: Philippe Roger Bovy, Joseph Gerace Rico, Thomas Edward Rogers
  • Meta-guanidine, urea, thiourea or azacyclic amino benzoic acid compounds and derivatives thereof
    Patent number: 6028223
    Abstract: The present invention relates to a class of compounds represented by the Formula I ##STR1## or a pharmaceutically acceptable salt thereof, wherein A is ##STR2## pharmaceutical compositions thereof and methods of using such compounds and compositions as .alpha..sub.v .beta..sub.3 antagonists.
    Type: Grant
    Filed: August 27, 1996
    Date of Patent: February 22, 2000
    Assignee: G. D. Searle & Co.
    Inventors: Peter Gerrard Ruminski, Michael Clare, Paul Waddell Collins, Bipinchandra Nanubhai Desai, Richard John Lindmark, Joseph Gerace Rico, Thomas Edward Rogers, Mark Andrew Russell
  • Platelet aggregation inhibitors containing C-terminal aminergic side chain amino acid residues
    Patent number: 5811398
    Abstract: This invention relates to compounds having the following formula ##STR1## or pharmaceutically acceptable salt thereof which are useful in the inhibition of platelet aggregation, to pharmaceutical compositions containing such compounds, and to a method of inhibiting platelet aggregation in mammals by administering such compounds and compositions.
    Type: Grant
    Filed: April 11, 1995
    Date of Patent: September 22, 1998
    Assignee: G. D. Searle & Co.
    Inventors: Norman Anthony Abood, Philippe Roger Bovy, Daniel Lee Flynn, Joseph Gerace Rico, Thomas Edward Rogers