Abstract: In an embodiment, a respiratory device is disclosed. The respiratory device may include a nasal device. The respiratory device may also include a conveyor device coupled with the nasal device. The respiratory device may further include an oral device, wherein the oral device may include an adjustment nut sized to couple with the conveyor device.

Abstract: In an embodiment, a respiratory device is disclosed. The respiratory device may include or comprise a nasal device. The respiratory device may also include or comprise a conveyor device coupled with the nasal device. The respiratory device may further include or comprise an oral device, wherein the oral device may include or comprise an adjustment nut sized to couple with the conveyor device.

Abstract: In an embodiment, a respiratory shield is disclosed. The respiratory shield is sized to be coupled with a respiratory device having a nasal air intake member so as to be positioned along an oral airflow axis.

Abstract: In an embodiment, a respiratory shield is disclosed. The respiratory shield is sized to be coupled with a respiratory device having a nasal air intake member so as to be positioned along an oral airflow axis.

Abstract: Two nasal breathing devices are supplied with continuous positive airway pressure for alleviation of sleep apnea. The two nasal breathing devices are each supported on a spiral flexible supply tube. The supply tubes pass through a block. The block is supported on the patient's head below his nostrils. A stop nut is threaded on each of the spiral flexible supply tubes. The supply tubes and nasal breathing devices are individually adjustable by rotating the stop nut on each of the supply tubes. In this way, the nasal breathing devices are individually adjusted for proper nasal contact and sealing.

Abstract: Agents that modulate an interaction of an FBL2 protein with an NS5A or NS5B Flaviviridae protein in a mixture are identified by contacting the mixture with a candidate agent under conditions wherein but for the presence of the agent, the FBL2 protein and the Flaviviridae protein engage in a reference interaction; and detecting an agent-biased interaction. Flaviviridae replication is inhibited by contacting a Flaviviridae-infected cell with an FBL2-specific reagent; and detecting a resultant Flaviviridae replication inhibition.

Abstract: Permissiveness of human cells to replication of susceptible pathogenic human viruses is reduced by treating the cells with a selective inhibitor of prenylation of a host cell protein. Target viruses, especially Flaviviridae, are predetermined to lack a CXXX box and prenylated viral protein, and to be replication-dependent on host protein prenylation. The general method comprises (a) contacting human cells subject to infection by the virus with an effective amount of a selective inhibitor of a prenylation enzyme of the cells; and (b) confirming a resultant reduction in permissiveness of the cells to replication of the virus. Targeted enzymes include prenyl biosynthetic enzyme like HMG CoA reductase farnesyl and/or geranylgeranyl transferase enzymes.

Abstract: The apparatus is configured to deliver breathable air under continuous positive air pressure to a person who requires such treatment. The apparatus includes a dentally stabilized platform and a nose mask, nose piece or nasal tubes resiliently mounted on the platform and urged toward nasal engagement and rhinal seal. In the case of configurations including nose masks and nose pieces, the force applied from the dentally stabilized platform is through a resilient connection. Various nose masks, nose piece and nostril engaging air tubes carrying nasal pads are disclosed. In each case, the resilient mounting on the dentally stabilized platform provides the necessary air seal. Air which is enhanced by medication or added oxygen may be supplied by the apparatus.

Abstract: Apparatus for alleviating a variety of breathing disorders, having a moldable mouthpiece clamped between the upper and lower teeth of the user so that a bracket outwardly projects from between the lips of the user in cantilevered fashion. The mouthpiece maintains the lower jaw forward to alleviate snoring problems by maintaining the throat clear. A nasal air delivery device is supported on the bracket and includes a pair of breathable air conducting tubes which terminate immediately adjacent to the user's nostrils. A sealing device disposed between the bracket and the nose prevents breathable air leakage, and a chin support carried on the tubes cooperates with the mouthpiece to stabilize and retain the nasal air delivery device in position on the facial area of the user.

Abstract: Two identical handles are configured for insertion into the core of a stretch-wrap roll. A substantially rigid hand grip is forward on each handle so that the hand grips can be grasped in the two hands for position guidance of the stretch-wrap roll. The handle grips can be carried in the gloved hand and can be run free or squeezed for braking control during stretch-wrap film winding. Each handle is molded of synthetic polymer composition material to be sufficiently rigid to provide the necessary support, but the plug inserted into the core is configured and sized to be somewhat resilient to facilitate insertion into and removal from the core.

Abstract: Stretch-wrap film on a roll is utilized by manual grasp on handles mounted on each end of the roll and freely rotatable thereon. A brake ring under at least one index finger can be clamped by that finger onto the spindle running with the stretch-wrap film roll, to apply braking and consequent stretch-wrap film tension.

Abstract: Stretch wrap film is wound on a mandrel or core which is longer than the roll of film to extend out of both ends. A rotatable handle is mounted on the core outboard of the film. Relative braking between the handle and core is adjusted by means of a screwthread which tightens a friction brake. The dispenser is carried around an article to be wrapped and the tension of the film is controlled by adjusting the brake by rotating its controlling nut. With a large core, an extension can be attached to a plug therein. Furthermore, instead of a spiral surface as on a nut and stud, a spring may be used to control brake force.

Abstract: Stretch wrapper machine is mounted upon a pallet carrier so that, as a loaded pallet is carried, it is stretch-wrapped.