Patents by Inventor Joseph H. Burchenal

Joseph H. Burchenal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-leukemic beta-glycosyl C-nucleosides
    Patent number: 4584369
    Abstract: Beta-glycosyl C-nucleoside compounds showing growth inhibitory activity against leukemic cells, of the following formula, are provided: ##STR1## wherein X is NR.sub.10, S or OR.sub.10 is H or alkyl with 1 to 6 carbon atoms. ##STR2## wherein R.sub.6, R.sub.7 and R.sub.8 are independently selected from H or alkyl of 1 to 6 carbon atoms; or ##STR3## wherein R.sub.16, R.sub.11 and R.sub.12 are independently selected from H or alkyl of 1-6 carbon atoms;R.sub.3 is OH, SR.sub.13, or OR.sub.9 ;R.sub.4 is OH, SR.sub.14, or OR.sub.15 ;R.sub.9, R.sub.13, R.sub.14 and R.sub.15 are individually selected from C.sub.1 -C.sub.6 alkyl and C.sub.1 to C.sub.6 acyl;R.sub.5 is OH or H,R'.sub.5 is OH or H with the provison that at least one of R.sub.5 or R'.sub.5 is H; excluding 2-deazoxoformycin; andHCl salts thereof.
    Type: Grant
    Filed: April 2, 1984
    Date of Patent: April 22, 1986
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Robert S. Klein, Muill Lim, Wuyun Ren, Joseph H. Burchenal
  • Complexes of square planar platinum II compounds and N-methyl glucamine
    Patent number: 4376782
    Abstract: Complexes or salts of square planar platinum(II) compounds and N-methyl glucamine, prepared by reacting a platinum(II) compound with N-methyl glucamine in an aqueous medium, are effective anti-tumor agents.
    Type: Grant
    Filed: May 21, 1980
    Date of Patent: March 15, 1983
    Assignee: Research Corporation
    Inventors: John Turkevich, Joseph H. Burchenal
  • 2,2'-Anhydro-.beta.-D-arabinofuranosyl-5-fluorocytosine
    Patent number: 4104461
    Abstract: A novel derivative of 1-.beta.-D-arabinofuranose namely the 5-fluorocytosine derivative has been prepared and found to have excellent activity against mouse leukemia.
    Type: Grant
    Filed: April 16, 1973
    Date of Patent: August 1, 1978
    Assignee: Research Corporation
    Inventors: Jack J. Fox, Joseph H. Burchenal