Patents by Inventor Joseph H. Hedley

Joseph H. Hedley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Design, synthesis and use of synthetic nucleotides comprising charge mass tags
    Patent number: 11180523
    Abstract: Embodiments of the present disclosure relate generally to reporter compositions which are synthetic nucleotides that comprise nucleotides with a high charge mass moiety attached thereto via a linker molecule. The linker molecules can vary in length in part to enable the high charge mass moiety to extend out from a DNA polymerase complex so that polymerization may not be influenced.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: November 23, 2021
    Assignee: QUANTUMDX GROUP LIMITED
    Inventors: Jonathan J. O'Halloran, Joseph H. Hedley
  • Sorbent material for separating bio-macromolecules
    Patent number: 10792640
    Abstract: A sorbent material is disclosed for the one-step separation of bio-macromolecules in a single pass extraction of DNA from complex mixtures of molecules and chemicals. In one embodiment, the sorbent material comprises a silanized material at least partially coated or formed with a polymer selected from the group consisting of a poly(aryl methacrylate), a poly(aryl acrylate), a poly(heteroaryl methacrylate, a poly(heteroaryl acrylate) and a copolymer thereof.
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: October 6, 2020
    Assignee: QUANTUMDX GROUP LIMITED
    Inventors: Jonathan James O'Halloran, Joseph H. Hedley, Sam Whitehouse, Marc Flanagan, John Tyson, Rachael Dixon, Sam Bhatt, Emily Crozier, Chris Howell
  • Design, synthesis and use of synthetic nucleotides comprising charge mass tags
    Patent number: 10759824
    Abstract: Embodiments of the present disclosure relate generally to reporter compositions which are synthetic nucleotides that comprise nucleotides with a high charge mass moiety attached thereto via a linker molecule. The linker molecules can vary in length in part to enable the high charge mass moiety to extend out from a DNA polymerase complex so that polymerization may not be influenced.
    Type: Grant
    Filed: January 4, 2016
    Date of Patent: September 1, 2020
    Assignee: QUANTUMDX GROUP LIMITED
    Inventors: Jonathan O'Halloran, Joseph H. Hedley
  • DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS
    Publication number: 20190248827
    Abstract: Embodiments of the present disclosure relate generally to reporter compositions which are synthetic nucleotides that comprise nucleotides with a high charge mass moiety attached thereto via a linker molecule. The linker molecules can vary in length in part to enable the high charge mass moiety to extend out from a DNA polymerase complex so that polymerization may not be influenced.
    Type: Application
    Filed: April 26, 2019
    Publication date: August 15, 2019
    Inventors: Jonathan J. O'Halloran, Joseph H. Hedley
  • Design, synthesis and use of synthetic nucleotides comprising charge mass tags
    Patent number: 10273261
    Abstract: Embodiments of the present disclosure relate generally to reporter compositions which are synthetic nucleotides that comprise nucleotides with a high charge mass moiety attached thereto via a linker molecule. The linker molecules can vary in length in part to enable the high charge mass moiety to extend out from a DNA polymerase complex so that polymerization may not be influenced.
    Type: Grant
    Filed: January 3, 2017
    Date of Patent: April 30, 2019
    Assignee: QUANTUMDX GROUP LIMITED
    Inventors: Jonathan J. O'Halloran, Joseph H. Hedley
  • DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS
    Publication number: 20190004055
    Abstract: Embodiments of the present disclosure relate generally to reporter compositions which are synthetic nucleotides that comprise nucleotides with a high charge mass moiety attached thereto via a linker molecule. The linker molecules can vary in length in part to enable the high charge mass moiety to extend out from a DNA polymerase complex so that polymerization may not be influenced.
    Type: Application
    Filed: January 3, 2017
    Publication date: January 3, 2019
    Inventors: Jonathan J. O'Halloran, Joseph H. Hedley
  • SORBENT MATERIAL FOR SEPARATING BIO-MACROMOLECULES
    Publication number: 20170282154
    Abstract: A sorbent material is disclosed for the one-step separation of bio-macromolecules in a single pass extraction of DNA from complex mixtures of molecules and chemicals. In one embodiment, the sorbent material comprises a silanized material at least partially coated or formed with a polymer selected from the group consisting of a poly(aryl methacrylate), a poly(aryl acrylate), a poly(heteroaryl methacrylate, a poly(heteroaryl acrylate) and a copolymer thereof.
    Type: Application
    Filed: September 10, 2015
    Publication date: October 5, 2017
    Applicant: QuantuMDx Group Limited
    Inventors: Jonathan James O'HALLORAN, Joseph H. HEDLEY, Sam WHITEHOUSE, Marc FLANAGAN, John TYSON, Rachael DIXON, Sam BHATT, Emily CROZIER, Chris HOWELL
  • DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS
    Publication number: 20160139133
    Abstract: Embodiments of the present disclosure relate generally to reporter compositions which are synthetic nucleotides that comprise nucleotides with a high charge mass moiety attached thereto via a linker molecule. The linker molecules can vary in length in part to enable the high charge mass moiety to extend out from a DNA polymerase complex so that polymerization may not be influenced.
    Type: Application
    Filed: January 4, 2016
    Publication date: May 19, 2016
    Inventors: Jonathan O'Halloran, Joseph H. Hedley
  • METHODS AND KIT FOR NUCLEIC ACID SEQUENCING
    Publication number: 20150276709
    Abstract: Various embodiments of the present disclosure generally relate to molecular biological protocols, equipment and reagents for the sequencing of long individual polynucleotide molecules.
    Type: Application
    Filed: August 5, 2013
    Publication date: October 1, 2015
    Applicant: QuantuMDx Group Limited
    Inventors: Jonathan O'Halloran, Christopher Adams, Joseph H. Hedley, Sam Whitehouse