Patents by Inventor Joseph H. Phillips

Joseph H. Phillips has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated mammalian monocyte cell genes; related reagents
    Publication number: 20040143858
    Abstract: Nucleic acids encoding various monocyte cell proteins from a primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Application
    Filed: February 11, 2004
    Publication date: July 22, 2004
    Applicant: Schering Corporation, a New Jersey corporation
    Inventors: Gosse Jan Adema, Linde Meyaard, Daniel M. Gorman, Terrill K. McClanahan, Sandra M. Zurawski, Gerard Zurawski, Lewis L. Lanier, Joseph H. Phillips
  • Mammalian cell membrane proteins; related reagents
    Publication number: 20040132085
    Abstract: The purification and isolation of various genes which encode mammalian cell surface polypeptides. Nucleic acids, proteins, antibodies, and other reagents useful in modulating development of cells, e.g., lymphoid and myeloid, are provided, along with methods for their use.
    Type: Application
    Filed: February 10, 2004
    Publication date: July 8, 2004
    Applicant: Schering Corporation, a New Jersey corporation
    Inventors: Alexander B.H. Bakker, Joseph H. Phillips, Lewis L. Lanier
  • Methods of modulating CD200 receptors
    Publication number: 20030223991
    Abstract: Provided are methods for modulating activity of the immune system using agonists or antagonists of a CD200 receptor. Also provided are methods of treatment and diagnosis of immune disorders.
    Type: Application
    Filed: March 13, 2003
    Publication date: December 4, 2003
    Inventors: Holly M. Cherwinski, Michael E. Bigler, Jonathon D. Sedgwick, Joseph H. Phillips
  • Isolated mammalian membrane protein genes; related reagents
    Publication number: 20030162955
    Abstract: Nucleic acids encoding various lymphocyte cell proteins from a primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Application
    Filed: October 11, 2002
    Publication date: August 28, 2003
    Inventors: Lionel Chalus, Ahn B. Quan, Elizabeth Esther Mary Bates, Daniel M. Gorman, Sem Saeland, Serge J. E. Lebecque, Joseph H. Phillips
  • Isolated mammalian monocyte cell genes; related reagents
    Publication number: 20030105303
    Abstract: Nucleic acids encoding various monocyte cell proteins from a primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Application
    Filed: November 8, 2002
    Publication date: June 5, 2003
    Applicant: Schering Corporation, a New Jersey corporation
    Inventors: Gosse Jan Adema, Linde Meyaard, Daniel M. Gorman, Terrill K. McClanahan, Sandra M. Zurawski, Gerard Zurawski, Lewis L. Lanier, Joseph H. Phillips
  • Use of bispecific antibodies to regulate immune responses
    Publication number: 20030077282
    Abstract: The invention relates generally to the field of immunology, in particular, to bispecific antibodies. Methods for designing a bispecific antibody for use in treating diseases relating to the immune system are disclosed. Specific examples relate to bispecific antibodies which recognize an activating receptor and an inhibiting receptor.
    Type: Application
    Filed: October 11, 2002
    Publication date: April 24, 2003
    Inventors: Michael Eric Bigler, Holly Marie Cherwinski, Joseph H. Phillips
  • Antibodies that specifically bind DNAX leukocyte associated immunoglobulin-like receptor
    Patent number: 6479638
    Abstract: Nucleic acids encoding various monocyte cell proteins from a primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using reagents relating to nucleic acids encoding monocyte cell proteins, and diagnostic kits, are also provided.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: November 12, 2002
    Assignee: Schering Corporation
    Inventors: Gosse Jan Adema, Linde Meyaard, Daniel M. Gorman, Terrill K. McClanahan, Sandra M. Zurawski, Gerard Zurawski, Lewis L. Lanier, Joseph H. Phillips, Jr.
  • Nucleic acids encoding mammalian cell membrane protein MDL-1
    Patent number: 6416973
    Abstract: The purification and isolation of various genes which encode mammalian cell surface polypeptides. Nucleic acids, proteins, antibodies, and other reagents useful in modulating development of cells, e.g., lymphoid and myeloid, are provided, along with methods for their use.
    Type: Grant
    Filed: July 31, 1998
    Date of Patent: July 9, 2002
    Assignee: Schering Corporation
    Inventors: Alexander B. H. Bakker, Joseph H. Phillips, Lewis L. Lanier
  • Ig superfamily `dlair` receptors expressed in monocytes
    Patent number: 6140076
    Abstract: DNA clones encoding a receptor in the Ig superfamily and a related soluble variant have been isolated from a human monocyte library. The invention provides receptor polypeptides, nucleic acids encoding them, expression vectors, and transformed cells for recombinant production of the polypeptides.
    Type: Grant
    Filed: December 5, 1997
    Date of Patent: October 31, 2000
    Assignee: Schering Corporation
    Inventors: Gosse Jan Adema, Linde Meyaard, Daniel M. Gorman, Terrill K. McClanahan, Lewis L. Lanier, Joseph H. Phillips, Jr.
  • Purified mammalian NK antigens and related reagents
    Patent number: 5965401
    Abstract: NK cell surface antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this antigen. Methods of using those reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: October 24, 1996
    Date of Patent: October 12, 1999
    Assignee: Schering Corporation
    Inventors: Chiwen Chang, Lewis L. Lanier, Joseph H. Phillips, Jr.
  • Nucleic acids encoding kp43 protein and antigenic fragments thereof
    Patent number: 5811284
    Abstract: The invention provides nucleic acids and polypeptides encoding an NK cell surface antigen from a mammal, as well as antibodies that specifically bind the NK cell surface antigen. Methods of using the nucleic acids, polypeptides, and antibodies are provided, including diagnostic kits comprising one or more of these reagents.
    Type: Grant
    Filed: May 20, 1996
    Date of Patent: September 22, 1998
    Assignees: Schering Corporation, Jose Aramburu Beltran, Miguel Lopez-Botet
    Inventors: Chiwen Chang, Jose Aramburu Beltran, Miguel Lopez-Botet, Joseph H. Phillips, Jr., Lewis L. Lanier
  • Antibodies to mammalian NK antigens and uses
    Patent number: 5770387
    Abstract: Antibodies which specifically bind to an NK cell surface antigen from a mammal, reagents related thereto, including purified proteins, specific antibodies, and nucleic acids encoding said antigen. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: June 28, 1996
    Date of Patent: June 23, 1998
    Assignees: Schering Corporation, The Board of Trustees of The Leland Stanford Junior University
    Inventors: Virginia M. Litwin, Jennifer E. Gumperz, Peter R. Parham, Joseph H. Phillips, Jr., Lewis L. Lanier
  • CD3 .zeta. co-associated complex on CD16.sup.- NK cells
    Patent number: 5124251
    Abstract: A novel protein complex is disclosed which is co-associated with CD3.zeta. on CD16.sup.- NK cells. A purified form of the protein complex, a gene encoding the protein complex and method of producing the purified protein complex also are disclosed. Antibodies that bind to the protein complex and methods for their use further are disclosed.
    Type: Grant
    Filed: January 31, 1990
    Date of Patent: June 23, 1992
    Assignee: Becton, Dickinson and Company
    Inventors: Lewis L. Lanier, Joseph H. Phillips
  • Method of purging residual tumor cells in vitro with lymphokine activated cytotoxic cells
    Patent number: 5041289
    Abstract: A method is disclosed for removing residual tumor cells from a patient with a neoplastic disorder by treating in vitro cell preparation with lymphokine activated cytotoxic cells.
    Type: Grant
    Filed: November 13, 1987
    Date of Patent: August 20, 1991
    Assignee: Becton Dickinson and Company
    Inventors: Joseph H. Phillips, Arnon Nagler, Lewis L. Lanier
  • Identification of NK cells and cytotoxic T lymphocytes
    Patent number: 4895796
    Abstract: A method for distinguishing between NK cells and T lymphocytes is provided, which comprises contacting a sample containing lymphocytes with a first reagent comprising anti-CD3 and a first detectable label and a second reagent comprising a mixture of anti-CD16 and anti-GP160 (Leu-19) both labeled with a second detectable label, and identifying cells that react with the reagents, whereby cells that react with the first reagent are identified as T lymphocytes, and cells that react only with the second reagent are identified as NK cells. Cells that react with both reagents are identified as a unique subset of T lymphocytes some of which may mediate MHC unrestricted cytolysis.
    Type: Grant
    Filed: January 6, 1988
    Date of Patent: January 23, 1990
    Assignee: Becton Dickinson and Company
    Inventors: Lewis L. Lanier, Joseph H. Phillips, Anne L. Jackson