Patents by Inventor Joseph H. Smith

Joseph H. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and apparatus for sequential amplification reactions
    Patent number: 12123052
    Abstract: The invention provides methods and apparatus for carrying out multiple amplification reactions in a single reaction chamber by successive cycles of loading reaction mixture, amplifying, and removing spent reaction mixture in a fluidly closed reaction system. In particular, the present invention allows amplification of a plurality of target polynucleotides from a single sample by carrying out under closed-loop control successive amplifications of different target polynucleotides from different portions of the sample.
    Type: Grant
    Filed: December 22, 2020
    Date of Patent: October 22, 2024
    Assignee: Cepheid
    Inventors: Joseph H. Smith, David H. Persing, Alan Wortman, Ronald Chang, David Swenson
  • METHODS AND APPARATUS FOR SEQUENTIAL AMPLIFICATION REACTIONS
    Publication number: 20210285025
    Abstract: The invention provides methods and apparatus for carrying out multiple amplification reactions in a single reaction chamber by successive cycles of loading reaction mixture, amplifying, and removing spent reaction mixture in a fluidly closed reaction system. In particular, the present invention allows amplification of a plurality of target polynucleotides from a single sample by carrying out under closed-loop control successive amplifications of different target polynucleotides from different portions of the sample.
    Type: Application
    Filed: December 22, 2020
    Publication date: September 16, 2021
    Inventors: Joseph H. Smith, David H. Persing, Alan Wortman, Ronald Chang, David Swenson
  • Methods and apparatus for sequential amplification reactions
    Patent number: 10907202
    Abstract: The invention provides methods and apparatus for carrying out multiple amplification reactions in a single reaction chamber by successive cycles of loading reaction mixture, amplifying, and removing spent reaction mixture in a fluidly closed reaction system. In particular, the present invention allows amplification of a plurality of target polynucleotides from a single sample by carrying out under closed-loop control successive amplifications of different target polynucleotides from different portions of the sample.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: February 2, 2021
    Assignee: Cepheid
    Inventors: Joseph H. Smith, David H. Persing, Alan Wortman, Ronald Chang, David Swenson
  • METHODS AND APPARATUS FOR SEQUENTIAL AMPLIFICATION REACTIONS
    Publication number: 20180187243
    Abstract: The invention provides methods and apparatus for carrying out multiple amplification reactions in a single reaction chamber by successive cycles of loading reaction mixture, amplifying, and removing spent reaction mixture in a fluidly closed reaction system. In particular, the present invention allows amplification of a plurality of target polynucleotides from a single sample by carrying out under closed-loop control successive amplifications of different target polynucleotides from different portions of the sample.
    Type: Application
    Filed: December 20, 2017
    Publication date: July 5, 2018
    Inventors: Joseph H. Smith, David H. Persing, Alan Wortman, Ronald Chang, David Swenson
  • Methods and apparatus for sequential amplification reactions
    Patent number: 9873909
    Abstract: The invention provides methods and apparatus for carrying out multiple amplification reactions in a single reaction chamber by successive cycles of loading reaction mixture, amplifying, and removing spent reaction mixture in a fluidly closed reaction system. In particular, the present invention allows amplification of a plurality of target polynucleotides from a single sample by carrying out under closed-loop control successive amplifications of different target polynucleotides from different portions of the sample.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: January 23, 2018
    Assignee: Cepheid
    Inventors: Joseph H. Smith, David H. Persing, Alan Wortman, Ronald Chang, David Swenson
  • METHODS AND APPARATUS FOR SEQUENTIAL AMPLIFICATION REACTIONS
    Publication number: 20150176057
    Abstract: The invention provides methods and apparatus for carrying out multiple amplification reactions in a single reaction chamber by successive cycles of loading reaction mixture, amplifying, and removing spent reaction mixture in a fluidly closed reaction system. In particular, the present invention allows amplification of a plurality of target polynucleotides from a single sample by carrying out under closed-loop control successive amplifications of different target polynucleotides from different portions of the sample.
    Type: Application
    Filed: November 25, 2014
    Publication date: June 25, 2015
    Inventors: Joseph H. Smith, David H. Persing, Alan Wortman, Ronald Chang, David Swenson
  • Methods and apparatus for sequential amplification reactions
    Patent number: 8900828
    Abstract: The invention provides methods and apparatus for carrying out multiple amplification reactions in a single reaction chamber by successive cycles of loading reaction mixture, amplifying, and removing spent reaction mixture in a fluidly closed reaction system. In particular, the present invention allows amplification of a plurality of target polynucleotides from a single sample by carrying out under closed-loop control successive amplifications of different target polynucleotides from different portions of the sample.
    Type: Grant
    Filed: April 30, 2007
    Date of Patent: December 2, 2014
    Assignee: Cepheid
    Inventors: Joseph H. Smith, David H. Persing, Alan Wortman, Ronald Chang, David Swenson
  • Tilt to clean gutter system
    Patent number: 5335460
    Abstract: A hinged hanger system for pivotably attaching a rain gutter to the fascia of a building beneath the edge of a roof comprising a plurality of hinged hangers for mounting and supporting the rain gutter in a tiltable position, the hangers consisting of an "L" shaped bracket and a hinge section nestled within horizontal supports and pivotably hinged to the horizontal supports, and a pulley system with lines attached to the rain gutter for tilting the gutter to a dumping position and resetting the gutter to a receiving position.
    Type: Grant
    Filed: May 7, 1993
    Date of Patent: August 9, 1994
    Inventor: Joseph H. Smith, Jr.
  • Water purification process
    Patent number: 4336140
    Abstract: Water of low solids content is purified by ion exchange treatment in separate beds with anion and cation exchange resins, the rate of flow of water through the last bed at least being fast. The beds are usually shallow and the flow rate through the last bed at least, and generally through all the beds, is at least 100 meters per hour. Apparatus suitable for use in such a process comprises a tower including supports for holding the beds one above the other and means for passing the water to be treated vertically through the tower.
    Type: Grant
    Filed: September 12, 1980
    Date of Patent: June 22, 1982
    Assignee: Permutit-Boby Limited
    Inventors: Joseph H. Smith, Trevor A. Peploe