Patents by Inventor Joseph Hellerbach

Joseph Hellerbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thienotriazolodiazepine derivatives
    Patent number: 4155913
    Abstract: Novel thienotriazolodiazepine derivatives and processes for their preparation are described. These compounds are useful as anticonvulsants, muscle-relaxants and sedatives.
    Type: Grant
    Filed: October 14, 1977
    Date of Patent: May 22, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Joseph Hellerbach, Paul Zeller, Dieter Binder, Otto Hromatka
  • Benzophenone derivatives
    Patent number: 4005085
    Abstract: Benzophenone derivatives are produced which have the formula ##STR1## wherein R.sub.1 signifies hydrogen, nitro, halogen or trifluoromethyl; R.sub.2 represents hydrogen or halogen; R.sub.3, R.sub.4 and R.sub.5 are the same or different and signify hydrogen or lower alkyl; R.sub.6 and R.sub.7 each represent lower alkyl or together with the nitrogen atom form a morpholino, 4-(lower alkyl)-1-piperazinyl, 1-pyrrolidinyl or piperidino group, A signifies an alkylene group with 2 to 8 C atoms and Y represents oxygen or a group ##STR2## R.sub.8 and R.sub.9 each signifying lower alkyl or together signifying lower alkylene.The benzophenone derivatives and their pharmaceutically acceptable salts exhibit sedative, anti-convulsant, muscle relaxant and anxiolytic activities.Also provided are methods for the preparation of these compounds.
    Type: Grant
    Filed: November 22, 1974
    Date of Patent: January 25, 1977
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Joseph Hellerbach, Andre Szente
  • 1-Polyhydroxy alkyl-1,4-benzodiazepin-2-ones
    Patent number: 3963777
    Abstract: Novel 1,4-benzodiazepin-2-ones bearing a polyhydroxyalkyl group in the 1-position are disclosed. These 1-substituted benzodiazepins are useful as muscle relaxant, anti-convulsant and sedative agents.
    Type: Grant
    Filed: October 20, 1975
    Date of Patent: June 15, 1976
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Joseph Hellerbach, Henri Hoffmann, Guido Zanetti
  • Process for preparing alkyl (n-phenylsulfonyloxy) carbamates
    Patent number: 3954838
    Abstract: 1,4-Benzodiazepin-2-ones bearing an acylamidoalkyl-substituent in the 1-position and methods for the preparation thereof are disclosed. These 1,4-benzodiazepin-2-ones exhibit sedative, anti-convulsant and muscle relaxant activity.
    Type: Grant
    Filed: August 29, 1974
    Date of Patent: May 4, 1976
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Joseph Hellerbach, Armin Walser, Hermann Bretschneider, Werner Rudolph