Patents by Inventor Joseph Hirschberg

Joseph Hirschberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TOMATO PLANTS HAVING FRUIT WITH HIGH ZEAXANTHIN CONTENT
    Publication number: 20240052434
    Abstract: The present invention relates to tomato plants having fruit with elevated nutritional and health benefits, particularly fruit with elevated content of the carotenoid zeaxanthin, a carotenoid offering a range of health benefits, particularly thought to inhibit the progression of age-related macular degradation (AMD), the most prevalent cause of blindness in developed countries.
    Type: Application
    Filed: September 9, 2020
    Publication date: February 15, 2024
    Inventors: Joseph Hirschberg, Daniel Zamir, Uri Karniel, Amit Koch
  • Tomato plants having fruit with yellow and red segments
    Patent number: 10750693
    Abstract: Provided are tomato plants having fruit with red and yellow segments that appear across the fruit from the internal seed area to the most external layer of the epidermis. The present invention discloses that this phenotype, designated Arlecchino, is linked to insertion mutation within the Phytoene synthase 1 (Psy1) gene.
    Type: Grant
    Filed: July 5, 2016
    Date of Patent: August 25, 2020
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Joseph Hirschberg, Dani Zamir, Yaacov Micha Brog, Itay Zemach, Orly Dery
  • TOMATO PLANTS HAVING FRUIT WITH YELLOW AND RED SEGMENTS
    Publication number: 20190021251
    Abstract: Provided are tomato plants having fruit with red and yellow segments that appear across the fruit from the internal seed area to the most external layer of the epidermis. The present invention discloses that this phenotype, designated Arlecchino, is linked to insertion mutation within the Phytoene synthase 1 (Psy1) gene.
    Type: Application
    Filed: July 5, 2016
    Publication date: January 24, 2019
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Joseph HIRSCHBERG, Dani ZAMIR, Yaacov Micha BROG, Itay ZEMACH, Orly DERY
  • Organism with altered carotenoid content and method of producing same
    Patent number: 9453237
    Abstract: The present invention relates to means and methods for modifying the expression of a component in the carotenoid biosynthetic pathway to modify the production of carotenoid towards accumulation of at least one of phytoene, phytofluene, zeta carotene or combinations thereof. The present invention further relates to genetically altered organisms having elevated content of these carotenoids. The present invention further relates to genetically altered organisms having elevated content of these carotenoids, particularly in chromoplast-containing cells.
    Type: Grant
    Filed: March 9, 2011
    Date of Patent: September 27, 2016
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Joseph Hirschberg, Dani Zamir
  • ORGANISM WITH ALTERED CAROTENOID CONTENT AND METHOD OF PRODUCING SAME
    Publication number: 20130036518
    Abstract: The present invention relates to means and methods for modifying the expression of a component in the carotenoid biosynthetic pathway to modify the production of carotenoid towards accumulation of at least one of phytoene, phytofluene, zeta carotene or combinations thereof. The present invention further relates to genetically altered organisms having elevated content of these carotenoids. The present invention further relates to genetically altered organisms having elevated content of these carotenoids, particularly in chromoplast-containing cells.
    Type: Application
    Filed: March 9, 2011
    Publication date: February 7, 2013
    Applicant: YISSUM RESSEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD
    Inventors: Joseph Hirschberg, Dani Zamir
  • Tocopherol biosynthesis related genes and uses thereof
    Patent number: 7230165
    Abstract: The present invention relates to genes associated with the tocopherol biosynthesis pathway. More particularly, the present invention provides and includes nucleic acid molecules and proteins associated with genes that encode polypeptides associated with the tocopherol biosynthesis pathway. The present invention also provides methods for utilizing such agents, for example in gene isolation, gene analysis, and the production of transgenic plants. Moreover, the present invention includes transgenic plants modified to express the aforementioned polypeptides. In addition, the present invention includes methods for the production of products from the tocopherol biosynthesis pathway as well as in production of plants that are drought resistant.
    Type: Grant
    Filed: August 5, 2003
    Date of Patent: June 12, 2007
    Assignee: Monsanto Technology LLC
    Inventors: Susan R. Norris, Kim Lincoln, Mark S. Abad, Robert J. Eilers, Karen Kindle Hartsuyker, Joseph Hirschberg, Balasulojini Karunanandaa, Farhad Moshiri, Joshua C. Stein, Henry E. Valentin, Tyamagondlu V. Venkatesh
  • POLYNUCLEOTIDE MOLECULE FROM HAEMATOCOCCUS PLUVIALIS ENCODING A POLYPEPTIDE HAVING A ?-C-4-OXYGENASE ACTIVITY FOR BIOTECHNOLOGICAL PRODUCTION OF (3S,3'S) ASTAXANTHIN AND ITS SPECIFIC EXPRESSION IN CHROMOPLASTS OF HIGHER PLANTS
    Patent number: 6903245
    Abstract: The present invention relates, in general, to a biotechnological method for production of (3S,3?S) astaxanthin. In particular, the present invention relates to a peptide having a ?-C-4-oxygenase activity; a DNA segment coding for this peptide; an RNA segments coding for this peptide; a recombinant DNA molecule comprising a vector and the DNA segment; a host cell or organism containing the above described recombinant DNA molecule or DNA segment; and to a method of biotechnologically producing (3S,3?S) astaxanthin or a food additive containing (3S,3?S) astaxanthin, using the host.
    Type: Grant
    Filed: February 26, 2001
    Date of Patent: June 7, 2005
    Assignee: Yissum Research Development Company of The Hebrew University of Jerusalem
    Inventors: Joseph Hirschberg, Tamar Lotan
  • Polypeptides having carotenoids isomerase catalytic activity, nucleic acids encoding same and uses thereof
    Publication number: 20050022269
    Abstract: An isolated nucleic acid which comprises a polynucleotide encoding a polypeptide having an amino acid sequence at least 50%, similar to SEQ ID NO: 15 (carotenoid isomerase of tomato (Lycopersicon esculentum)), as determined using the Standard protein-protein BLAST [blastp] software of the NCBI, the polypeptide having carotenoids isomerase catalytic activity, the polypeptide encoded thereby and their uses.
    Type: Application
    Filed: July 18, 2002
    Publication date: January 27, 2005
    Inventors: Joseph Hirschberg, Tal Isaacson, Dani Zamir
  • Tocopherol biosynthesis related genes and uses thereof
    Publication number: 20040045051
    Abstract: The present invention relates to genes associated with the tocopherol biosynthesis pathway. More particulary the present invention provides and includes nucleic acid molecules and proteins associated with genes that encode polypeptides associated with the tocopherol biosynthesis pathway. The present invention also provides methods for utilizing such agents, for example in gene isolation, gene analysis, and the production of transgenic plants. Moreover, the present invention includes transgenic plants modified to express the aforementioned polypeptides. In addition, the present invention includes methods for the production of products from the tocopherol biosynthesis pathway as well as in production of plants that are drought resistant.
    Type: Application
    Filed: August 5, 2003
    Publication date: March 4, 2004
    Inventors: Susan R. Norris, Kim Lincoln, Mark S. Abad, Robert J. Eilers, Karen Kindle Hartsuyker, Joseph Hirschberg, Balasulojini Karunanandaa, Farhad Moshiri, Joshua C. Stein, Henry E. Valentin, Tyamagondlu V. Venkatesh
  • Polynucleotide molecule from Haematococcus pluvialis encoding a polypeptide having a beta-C-4-oxygenase activity for biotechnological production of (3S,3'S) astaxanthin and its specific expression in chromoplasts of higher plants
    Publication number: 20020053096
    Abstract: The present invention relates, in general, to a biotechnological method for production of (3S,3′S) astaxanthin. In particular, the present invention relates to a peptide having a &bgr;-C-4-oxygenase activity; a DNA segment coding for this peptide; an RNA segments coding for this peptide; a recombinant DNA molecule comprising a vector and the DNA segment; a host cell or organism containing the above described recombinant DNA molecule or DNA segment; and to a method of biotechnologically producing (3S,3′S) astaxanthin or a food additive containing (3S,3′S) astaxanthin, using the host.
    Type: Application
    Filed: February 26, 2001
    Publication date: May 2, 2002
    Inventors: Joseph Hirschberg, Tamar Lotan
  • Tomato gene B polynucleotides coding for lycopene cyclase
    Patent number: 6252141
    Abstract: An isolated complementary and genomic DNA segment encoding lycopene cyclase of the B locus of tomato are provided.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: June 26, 2001
    Assignee: Yissum Research and Development Company of the Hebrew University of Jerusalem
    Inventors: Joseph Hirschberg, Gil Ronen, Dany Zamir
  • Polynucleotide molecule from Haematococcus pluvialis encoding a polypeptide having a &bgr;-C-4-oxygenase activity for biotechnological production of (3S, 3'S) astaxanthin and its specific expression in chromoplasts of higher plants
    Patent number: 6218599
    Abstract: The present invention relates, in general, to a biotechnological method for production of (3S,3′S) astaxanthin. In particular, the present invention relates to a peptide having a &bgr;-C-4-oxygenase activity; a DNA segment coding for this peptide; an RNA segments coding for this peptide; a recombinant DNA molecule comprising a vector and the DNA segment; a host cell or organism containing the above described recombinant DNA molecule or DNA segment; and to a method of biotechnologically producing (3S,3′S) astaxanthin or a food additive containing (3S,3′S) astaxanthin, using the host.
    Type: Grant
    Filed: March 1, 1999
    Date of Patent: April 17, 2001
    Assignee: Yissum Research and Development Company of the Hebrew University of Jerusalem
    Inventors: Joseph Hirschberg, Tamar Lotan
  • Polynucleotide molecule from Haematococcus pluvialis encoding a polypeptide having a beta-C-4-oxygenase activity for biotechnological production of (3S, 3'S) astaxanthin and its specific expression in chromoplasts of higher plants
    Patent number: 5965795
    Abstract: The present invention relates, in general, to a biotechnological method for production of (3S,3'S) astaxanthin. In particular, the present invention relates to a peptide having a .beta.-C-4-oxygenase activity; a DNA segment coding for this peptide; an RNA segments coding for this peptide; a recombinant DNA molecule comprising a vector and the DNA segment; a host cell or organism containing the above described recombinant DNA molecule or DNA segment; and to a method of biotechnologically producing (3S,3'S) astaxanthin or a food additive containing (3S,3'S) astaxanthin, using the host.
    Type: Grant
    Filed: October 28, 1996
    Date of Patent: October 12, 1999
    Assignee: Yissum Research and Development Company of the Hebrew University of Jerusalem
    Inventors: Joseph Hirschberg, Tamar Lotan
  • Carotenoid-producing bacterial species and process for production of carotenoids using same
    Patent number: 5935808
    Abstract: A novel Paracoccus species type strain DSM 11574 which produces and secretes carotenoids such as .beta.-carotene, echinenone, .beta.-cryptoxanthin, canthaxanthin, adonirubin, cis-adonixanthin, adonixanthin, astaxanthin and zeaxanthin in vesicles; carotenoid containing vesicles; and a process for production of carotenoids comprising (a) culturing a bacterial species in an nutrient medium including sources of carbon, nitrogen and inorganic substances; and (b) recovering an individual carotenoid pigment or a mixture of carotenoid pigments from the cells, vesicles and/or medium.
    Type: Grant
    Filed: July 29, 1997
    Date of Patent: August 10, 1999
    Assignee: Yissum Research and Development Company of the Hebrew University of Jerusalem
    Inventors: Joseph Hirschberg, Mark Harker
  • Polynucleotide molecule from Haematococcus pluvialis encoding a polypeptide having a .beta.--C--4--oxygenase activity for biotechnological production of (3S,3S)astaxanthin
    Patent number: 5916791
    Abstract: The present invention relates, in general, to a biotechnological method for production of (3S,3'S) astaxanthin. In particular, the present invention relates to a peptide having a .beta.-C-4-oxygenase activity; a DNA segment coding for this peptide; a RNA segments coding for this peptide; a recombinant DNA molecule comprising a vector and the DNA segment; a host cell or organism containing the above described recombinant DNA molecule or DNA segment; and to a method of biotechnologically producing (3S,3'S) astaxanthin or a food additive containing (3S,3'S) astaxanthin, using the host.
    Type: Grant
    Filed: November 24, 1995
    Date of Patent: June 29, 1999
    Inventors: Joseph Hirschberg, Tamar Lotan
  • Lycopene cyclase gene
    Patent number: 5792903
    Abstract: A purified and isolated DNA sequence encoding lycopene cyclase.
    Type: Grant
    Filed: March 7, 1995
    Date of Patent: August 11, 1998
    Assignees: Yissum Research Development Company of Hebrew University of Jerusalem, University of Maryland
    Inventors: Joseph Hirschberg, Francis Xavier Cunningham, Jr., Elisabeth Gantt