Abstract: The pharmacokinetic profile of the SGLT2 inhibitor bexagliflozin can be improved by formulating it as an extended release tablet. Compared with standard immediate-release dosage forms these tablets can permit a lower peak plasma concentration, Cmax, while maintaining plasma concentrations at therapeutic levels for a desired period. This can be used, for instance, to administer lower doses while still providing the same pharmacological effect.

Abstract: A car tissue box holder is provided. The tissue box is secured to the sun visor of the vehicle by hook and loop or Velcro straps. A pair of straps securing a metal plate to the tissue box attaches to a magnet holder plate secured to the sun visor. The magnet holder plate has a magnetic component help by a plastic component of the magnet holder plate. The Velcro straps are thread through the respective plates. The plates allow adjustment to different sized of tissue box and sizes of sun visors and easy or removal of the tissue box.

Abstract: A detection system detects malfunctions in an autonomous farming vehicle during an autonomous routine using one or more models and data from sensors coupled to the autonomous farming vehicle. The models may include machine-learned models trained on the sensor data and configured to identify objects indicative of an operational or malfunctioning component within a tilling assembly such as a tilling shank or sweep. Additionally, a machine-learned model may be trained on sensor data to detect whether debris has plugged the tilling assembly of the autonomous farming vehicle. In response to detecting a malfunction or a plug, the detection system may modify the autonomous routine (e.g., pausing operation) or provide information for the malfunction to be addressed (e.g., the likely location of a malfunctioning sweep that has detached from the tilling assembly).

Abstract: Described herein is a protective coating composition that provides erosion and corrosion resistance to a coated article (such as a chamber component) upon the article's exposure to harsh chemical environment (such as hydrogen based and/or halogen based environment) and/or upon the article's exposure to high energy plasma. Also described herein is a method of coating an article with the protective coating using electronic beam ion assisted deposition, physical vapor deposition, or plasma spray. Also described herein is a method of processing wafer, which method exhibits, on average, less than about 5 yttrium based particle defects per wafer.

Abstract: A user equipment may determine a latency requirement of the user equipment, and may determine a first set of latencies between the user equipment and a first multi-access edge computing (MEC) device. The user equipment may determine a second set of latencies between the user equipment and a second MEC device, and may calculate a first violation probability based on the latency requirement and the first set of latencies. The user equipment may calculate a second violation probability based on the latency requirement and the second set of latencies, and may identify the first MEC device or the second MEC device based on the first violation probability and the second violation probability. The user equipment may selectively initiate a MEC handoff of the user equipment to the first MEC device or the second MEC device based on identifying the first MEC device or the second MEC device.

Abstract: A device may receive Internet of Things (IoT) data generated by a plurality of different IoT devices, and may group the IoT data into groups of data packages at configured time intervals or in response to events. The device may generate data notifications for the groups of data packages, and may provide the data notifications to a blockchain node, associated with the device and included in a network of blockchain nodes associated with data consumer devices, to cause the data notifications to be securely provided to corresponding ones of the data consumer devices. The device may receive, from one of the data consumer devices, a request for a data package of the groups, and may authenticate the one of the data consumer devices. The device may provide the data package to the one of the data consumer devices when authenticated.

Abstract: A car tissue box holder is provided. The tissue box is secured to the sun visor of the vehicle by hook and loop or Velcro straps. A pair of straps securing a metal plate to the tissue box attaches to a magnet holder plate secured to the sun visor. The magnet holder plate has a magnetic component help by a plastic component of the magnet holder plate. The Velcro straps are thread through the respective plates. The plates allow adjustment to different sized of tissue box and sizes of sun visors and easy or removal of the tissue box.

Abstract: A user equipment may determine a latency requirement of the user equipment, and may determine a first set of latencies between the user equipment and a first multi-access edge computing (MEC) device. The user equipment may determine a second set of latencies between the user equipment and a second MEC device, and may calculate a first violation probability based on the latency requirement and the first set of latencies. The user equipment may calculate a second violation probability based on the latency requirement and the second set of latencies, and may identify the first MEC device or the second MEC device based on the first violation probability and the second violation probability. The user equipment may selectively initiate a MEC handoff of the user equipment to the first MEC device or the second MEC device based on identifying the first MEC device or the second MEC device.

Abstract: A user equipment may determine a latency requirement of the user equipment, and may determine a first set of latencies between the user equipment and a first multi-access edge computing (MEC) device. The user equipment may determine a second set of latencies between the user equipment and a second MEC device, and may calculate a first violation probability based on the latency requirement and the first set of latencies. The user equipment may calculate a second violation probability based on the latency requirement and the second set of latencies, and may identify the first MEC device or the second MEC device based on the first violation probability and the second violation probability. The user equipment may selectively initiate a MEC handoff of the user equipment to the first MEC device or the second MEC device based on identifying the first MEC device or the second MEC device.

Abstract: A user equipment may determine a latency requirement of the user equipment, and may determine a first set of latencies between the user equipment and a first multi-access edge computing (MEC) device. The user equipment may determine a second set of latencies between the user equipment and a second MEC device, and may calculate a first violation probability based on the latency requirement and the first set of latencies. The user equipment may calculate a second violation probability based on the latency requirement and the second set of latencies, and may identify the first MEC device or the second MEC device based on the first violation probability and the second violation probability. The user equipment may selectively initiate a MEC handoff of the user equipment to the first MEC device or the second MEC device based on identifying the first MEC device or the second MEC device.

Abstract: The pharmacokinetic profile of the SGLT2 inhibitor bexagliflozin can be improved by formulating it as an extended release tablet. Compared with standard immediate-release dosage forms these tablets can permit a lower peak plasma concentration, Cmax, while maintaining plasma concentrations at therapeutic levels for a desired period. This can be used, for instance, to administer lower doses while still providing the same pharmacological effect.

Abstract: Techniques for fabricating ferroelectric materials and semiconductor devices using the materials. Material compositions including strontium, zirconium, titanium, and oxygen are disposed on a substrate material to produce ferroelectric devices.

Abstract: A salad shaker for selectively mixing a salad product with the dressing. In a storage/transportation position, salad stuffed in a bowl having a lid does not contact the dressing sealed in a container having a cover with a handle. In a mixing portion, the cover is removed from outside the shaker to release the dressing into the bowl for preparing the serving when desired.

Abstract: A modular, tree-like structure for holding or hanging potted plants is suitable as an indoor flower/herbs stand. A base on casters supports a height adjustable central stem. The central stem is assembled using a coupling device having means rotatably connecting a plurality of branch arms with brackets, or flower basket hooks, for supporting a plurality of potted plants in a horizontally tiered arrangement and un-obstructing tree configuration. The combination of various length/size brackets in a multi-tier arrangement which can rotate independent from the central stem, allows for an increased number of potted plants to be adequately displayed on a given floor surface.

Abstract: A method is provided for evaluating drug compounds based on their binding properties to human serum albumin wherein structural information at particular albumin binding regions is entered into a computer database and assessed with regard to particular contacting binding residues located in accordance with the invention. The information obtained through the computer database is thus useful in assessing and predicting drug interactions at albumin binding sites. Further, protein fragments including one or more albumin binding sites are provided which can be used in methods of assessing and designing drugs.

Abstract: A space division system (100) is disclosed, with the space division system (100) incorporating technology. The space division system (100) is disclosed as having a space divider (102) vertically suspended from a rail system (104). The rail system (104) includes a rail (106) with a pair of hanger clips (108) releasably secured to the rail (106) and capable of being moved along a continuum of the length of the rail (106). In one embodiment, the space divider (102) includes a main body (114) consisting of an opaque fabric. Associated with the main body (114) is lighting technology including a series of LED lights (116). Arrow lights (118) may be activated in an appropriate manner for emergency or other purposes. Color changing is also provided for purposes of wayfinding, signaling occupant activities or other external or internal circumstances.

Abstract: A high resolution structure of the hemalbumin binding complex is provided which includes the detailed atomic coordinates which reflect the binding site and the binding characteristics of the structure. This high resolution structure can be used in methods of determining the primary residues involved in gas binding, redox potential of iron, etc., and thus will be used to identify and optimize the gas binding characteristics of heme and albumin, so as to allow for the development of modified recombinant albumins containing heme and/or heme derivatives which have improved gas binding properties and which can be used for therapeutic purposes.

Abstract: A method is provided for evaluating drug compounds based on their binding properties to human serum albumin wherein structural information at particular albumin binding regions is entered into a computer database and assessed with regard to particular contacting binding residues located in accordance with the invention. The information obtained through the computer database is thus useful in assessing and predicting drug interactions at albumin binding sites. Further, protein fragments including one or more albumin binding sites are provided which can be used in methods of assessing and designing drugs.

Abstract: A space division system (100) is disclosed, with the space division system (100) incorporating technology. The space division system (100) is disclosed as having a space divider (102) vertically suspended from a rail system (104). The rail system (104) includes a rail (106) with a pair of hanger clips (108) releasably secured to the rail (106) and capable of being moved along a continuum of the length of the rail (106). In one embodiment, the space divider (102) includes a main body (114) consisting of an opaque fabric. Associated with the main body (114) is lighting technology including a series of LED lights (116). Arrow lights (118) may be activated in an appropriate manner for emergency or other purposes. Color changing is also provided for purposes of wayfinding, signaling occupant activities or other external or internal circumstances.

Abstract: A method is provided for increasing the safety and efficacy of albumin-binding drugs such as those used as anti-cancer, anti-infective, or anti-hypertensive drugs, or for numerous other conditions. In the preferred method, the invention modulates those drugs which bind at the IB site on human serum albumin by co-administering a compound which is highly tolerable to humans and which can bind competitively with those albumin-binding drugs at the IB binding site so as to increase the safety and efficacy of the drug. The invention is advantageous in that by administering the highly tolerable compound in a sufficient amount to compete with the targeted drug, the latter can be administered at a much lower dosage while maintaining or exceeding its potency. Compositions containing the combination of highly tolerable compound and albumin-bind drugs are also disclosed.