Patents by Inventor Joseph Irudayaraj

Joseph Irudayaraj has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11821892
    Abstract: The present invention provides oxygenized nanobubbles and their uses in imaging and cancer treatment when combined with therapeutic drugs and precise ultrasound beam steering.
    Type: Grant
    Filed: April 17, 2020
    Date of Patent: November 21, 2023
    Assignee: Purdue Research Foundation
    Inventors: Joseph Irudayaraj, Pushpak Bhandari
  • Publication number: 20220146522
    Abstract: The present disclosure relates to a novel method for lateral flow immunoassay (LFIA) by utilizing plasmonic enhancement strategy. More specifically, the present disclosure provides a plasmonic enhanced lateral flow sensor (pLFS) concept by introducing a liposome-based amplification of the colorimetric signals on the lateral flow platform for ultrasensitive detection of pathogens.
    Type: Application
    Filed: October 15, 2021
    Publication date: May 12, 2022
    Applicant: Purdue Research Foundation
    Inventors: Joseph Irudayaraj, Wen Ren
  • Publication number: 20200249221
    Abstract: The present invention provides oxygenized nanobubbles and their uses in imaging and cancer treatment when combined with therapeutic drugs and precise ultrasound beam steering.
    Type: Application
    Filed: April 17, 2020
    Publication date: August 6, 2020
    Applicant: Purdue Research Foundation
    Inventors: Joseph Irudayaraj, Pushpak Bhandari
  • Patent number: 10670581
    Abstract: The present invention provides oxygenized nanobubbles and their uses in imaging and cancer treatment when combined with therapeutic drugs and precise ultrasound beam steering.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: June 2, 2020
    Assignee: Purdue Research Foundation
    Inventors: Joseph Irudayaraj, Pushpak Bhandari
  • Publication number: 20200116729
    Abstract: The present disclosure relates to a novel method for lateral flow immunoassay (LFIA) by utilizing plasmonic enhancement strategy. More specifically, the present disclosure provides a plasmonic enhanced lateral flow sensor (pLFS) concept by introducing a liposome-based amplification of the colorimetric signals on the lateral flow platform for ultrasensitive detection of pathogens.
    Type: Application
    Filed: September 9, 2019
    Publication date: April 16, 2020
    Applicant: Purdue Research Foundation
    Inventor: Joseph Irudayaraj
  • Publication number: 20180252702
    Abstract: The present invention provides oxygenized nanobubbles and their uses in imaging and cancer treatment when combined with therapeutic drugs and precise ultrasound beam steering.
    Type: Application
    Filed: March 7, 2018
    Publication date: September 6, 2018
    Applicant: Purdue Research Foundation
    Inventors: Joseph Irudayaraj, Pushpak Bhandari
  • Patent number: 9968692
    Abstract: The present invention provides a nanobubble comprising a continuous outer shell, the outer shell comprising a cross-linked polymeric material, an inner wall of the continuous outer shell and a hollow core within the continuous outer shell. The nanobubble may be less than 250 nm in diameter. In a further aspect of the invention, the cross-linked polymeric material is a cellulose-based material.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: May 15, 2018
    Assignee: PURDUE RESEARCH FOUNDATION
    Inventors: Joseph Irudayaraj, Pushpak Bhandari
  • Publication number: 20160166716
    Abstract: The present invention provides a nanobubble comprising a continuous outer shell, the outer shell comprising a cross-linked polymeric material, an inner wall of the continuous outer shell and a hollow core within the continuous outer shell. The nanobubble may be less than 250 nm in diameter. In a further aspect of the invention, the cross-linked polymeric material is a cellulose-based material.
    Type: Application
    Filed: October 2, 2015
    Publication date: June 16, 2016
    Applicant: PURDUE RESEARCH FOUNDATION
    Inventors: Joseph Irudayaraj, Pushpak Bhandari
  • Publication number: 20120164717
    Abstract: An apparatus and method of characterizing cells having surface markers includes the use of functionalized probes, the probes having absorption spectra characteristic of a probe geometry. The probes are functionalized with biomolecules (biomarkers) capable of binding to the surface markers, and cells having a particular combination of probes having specific bound biomarkers are measured using a spectrum analyzer. A plurality of surface markers may be simultaneously measured using the spectral properties of the probes to differentiate the cells. The relative abundance of a plurality of surface markers may be determined simultaneously. Functionalized probes with several different aspect ratios were used in an experiment to demonstrate the use of functionalized probes for characterizing cancer cells. The functionalized gold nanorod probes when attached to magnetic particles may be used as a dual contrast agent for magnetic resonance imaging (MRI) and optical imaging and as a targeted drug delivery system.
    Type: Application
    Filed: July 11, 2008
    Publication date: June 28, 2012
    Inventor: Joseph Irudayaraj