Patents by Inventor Joseph Ischia

Joseph Ischia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9205102
    Abstract: Castrate resistant prostate cancer cell lines exhibiting resistance to the androgen-receptor antagonist enzaluatamide overexpress one or both of IGFBP-2 or IGFBP-5 when compared to non-resistant cell lines. Oligonucleotides that target IGFBP-2 and IGFBP-5 can be used to overcome this resistance or as part of a treatment program when administered concurrently with the administration of androgen-receptor antagonist treatments.
    Type: Grant
    Filed: December 4, 2014
    Date of Patent: December 8, 2015
    Assignee: The University of British Columbia
    Inventors: Martin E. Gleave, Joseph Ischia
  • Publication number: 20150157656
    Abstract: Castrate resistant prostate cancer cell lines exhibiting resistance to the androgen-receptor antagonist enzaluatamide overexpress one or both of IGFBP-2 or IGFBP-5 when compared to non-resistant cell lines. Oligonucleotides that target IGFBP-2 and IGFBP-5 can be used to overcome this resistance or as part of a treatment program when administered concurrently with the administration of androgen-receptor antagonist treatments.
    Type: Application
    Filed: December 4, 2014
    Publication date: June 11, 2015
    Inventors: Martin E. Gleave, Joseph Ischia