Patents by Inventor Joseph J. Buggy

Joseph J. Buggy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Uses of Selective Inhibitors of HDAC8 for Treatment of T-Cell Proliferative Disorders
    Publication number: 20080112889
    Abstract: Described herein are methods for treating a subject suffering from a T-cell lymphoma by administering to the subject a pharmaceutical composition containing a therapeutically effective amount of a selective inhibitor of histone deacetylase 8. Also described herein are methods for treating a subject suffering from a T-cell lymphoma by administering to the subject a population of autologous T-cells that have been exposed to a selective HDAC8 inhibitor composition ex vivo.
    Type: Application
    Filed: July 18, 2007
    Publication date: May 15, 2008
    Applicant: PHARMACYCLICS, INC.
    Inventors: Joseph J. Buggy, Sriram Balasubramanian
  • Hydroxamates as therapeutic agents
    Patent number: 7276612
    Abstract: The present invention is directed to certain hydroxamate derivatives that are useful in the treatment of hepatitis C. These compounds are also inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.
    Type: Grant
    Filed: April 6, 2004
    Date of Patent: October 2, 2007
    Assignee: Pharmacyclics, Inc.
    Inventors: Eric J. Verner, Martin Sendzik, Chitra Baskaran, Joseph J. Buggy, James Robinson