Patents by Inventor Joseph J. Florio

Joseph J. Florio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190162013
    Abstract: A method for applying a patch to a spacer discontinuity or other seal breach includes the step of applying pressure to the patch during the application of the patch to cause sealant carried by the patch to be injected into the spacer discontinuity. This step can be performed with or without the application of heat. Pressure is applied to the patch long enough to position the sealant entirely across the gap between the lites such that the sealant wets out against both interior glass surfaces. Pressure is also applied to the patch long enough to inject sealant into openings defining the discontinuity. A sealant is then applied over the entire patch. The structure of the patch and the patched IG unit are provided.
    Type: Application
    Filed: January 10, 2019
    Publication date: May 30, 2019
    Inventors: Leslie M. Canning, JR., Nathan T. Tuttle, Cody J. Walsh, Joseph D. Florio, Kenneth F. Wayman
  • Patent number: 8818510
    Abstract: A coupled/paired stimulus pulse is delivered to the heart at an inter-pulse interval following one of i) detection of an intrinsic depolarization or ii) delivery of a primary stimulus pulse. Capture resulting from the coupled/paired stimulus pulse is sensed for. In response to capture by a coupled/paired stimulus pulse, the inter-pulse interval is incrementally decreased by a first amount until there is no capture by a coupled/paired stimulus pulse. In response to no capture by a coupled/paired stimulus pulse, the inter-pulse interval is incrementally increased by a second amount greater than the first amount, until capture by a coupled/paired stimulus pulse is detected. Once capture is again detected, paired/coupled pacing is delivered at the inter-pulse interval which resulted in capture for a predetermined period of time or until loss of capture occurs.
    Type: Grant
    Filed: December 10, 2009
    Date of Patent: August 26, 2014
    Assignee: Pacesetter, Inc.
    Inventors: Gene A. Bornzin, Joseph J. Florio
  • Patent number: 8706224
    Abstract: Techniques are described for use with an implantable cardiac stimulation device for performing paired/coupled pacing either alone or in conjunction with dynamic overdrive/underdrive pacing. In one technique, dynamic overdrive/underdrive pacing is delivered to the ventricles using paired pulses during an episode of atrial fibrillation. The use of paired pulses during dynamic ventricular overdrive/underdrive pacing helps lower and stabilize the ventricular rate to thereby reduce the risk of a ventricular arrhythmia. In another technique, the inter-pulse interval between paired pulses is optimized to lengthen the resulting refractory period to improve hemodynamics. Preferably, the optimized inter-pulse interval is used when applying dynamic ventricular overdrive/underdrive pacing with paired pulses so that the benefits of both techniques are obtained. The optimization technique is also applicable to setting the coupling interval for use with coupled pacing.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: April 22, 2014
    Assignee: Pacesetter, In.
    Inventors: Gene A. Bornzin, Joseph J. Florio, Peter Boileau
  • Patent number: 8504144
    Abstract: Techniques for detecting tachyarrhythmia and also for preventing T-wave oversensing use signals filtered by a narrowband bradycardia filter in combination with signals filtered by a narrowband tachycardia filter. A separate wideband filter may also be used.
    Type: Grant
    Filed: July 11, 2007
    Date of Patent: August 6, 2013
    Assignee: Pacesetter, Inc.
    Inventors: Rupinder Bharmi, Jeffery D. Snell, Gene A. Bornzin, Joseph J. Florio, Peter Boileau
  • Patent number: 8265739
    Abstract: Techniques are provided for use in a pacemaker or implantable cardioverter/defibrillator (ICD) for distinguishing cardiac ischemia from other conditions affecting the morphology of electrical cardiac signals sensed within a patient, such as hypoglycemia, hyperglycemia or other systemic conditions. In one example, the device detects changes in morphological features of cardiac signals indicative of possible cardiac ischemia within the patient, such as changes in ST segment elevation within an intracardiac electrogram (IEGM). The device determines whether the changes in the morphological features are the result of spatially localized changes within a portion of the heart and then distinguishes cardiac ischemia from other conditions affecting the morphology of electrical cardiac signals based on that determination. In another example, the device exploits the interval between the peak of a T-wave (Tmax) and the end of the T-wave (Tend).
    Type: Grant
    Filed: January 17, 2008
    Date of Patent: September 11, 2012
    Assignee: Pacesetter, Inc.
    Inventors: Peter Boileau, Xiaoyi Min, Jong Gill, Rupinder Bharmi, Joseph J. Florio, Michael E. Benser, Gene A. Bornzin
  • Patent number: 8260404
    Abstract: Techniques for detecting tachyarrhythmia and also for preventing T-wave oversensing use signals filtered by a narrowband bradycardia filter in combination with signals filtered by a narrowband tachycardia filter. A separate wideband filter may also be used.
    Type: Grant
    Filed: July 11, 2007
    Date of Patent: September 4, 2012
    Assignee: Pacesetter, Inc.
    Inventors: Rupinder Bharmi, Jeffery D. Snell, Gene A. Bornzin, Joseph J. Florio, Peter Boileau
  • Publication number: 20120197149
    Abstract: Techniques are described for detecting ischemia, hypoglycemia or hyperglycemia based on intracardiac electrogram (IEGM) signals. Ischemia is detected based on a shortening of the interval between the QRS complex and the end of a T-wave (QTmax), alone or in combination with a change in ST segment elevation. Alternatively, ischemia is detected based on a change in ST segment elevation combined with minimal change in the interval between the QRS complex and the end of the T-wave (QTend). Hypoglycemia is detected based on a change in ST segment elevation along with a lengthening of either QTmax or QTend. Hyperglycemia is detected based on a change in ST segment elevation along with minimal change in QTmax and in QTend. By exploiting QTmax and QTend in combination with ST segment elevation, changes in ST segment elevation caused by hypo/hyperglycemia can be properly distinguished from changes caused by ischemia.
    Type: Application
    Filed: April 11, 2012
    Publication date: August 2, 2012
    Applicant: PACESETTER, INC.
    Inventors: Jong Gill, Peter Boileau, Rupinder Bharmi, Xiaoyi Min, Joseph J. Florio, Michael E. Benser, Gene A. Bornzin
  • Patent number: 8180441
    Abstract: Techniques are described for detecting ischemia, hypoglycemia or hyperglycemia based on intracardiac electrogram (IEGM) signals. Ischemia is detected based on a shortening of the interval between the QRS complex and the end of a T-wave (QTmax), alone or in combination with a change in ST segment elevation. Alternatively, ischemia is detected based on a change in ST segment elevation combined with minimal change in the interval between the QRS complex and the end of the T-wave (QTend). Hypoglycemia is detected based on a change in ST segment elevation along with a lengthening of either QTmax or QTend. Hyperglycemia is detected based on a change in ST segment elevation along with minimal change in QTmax and in QTend. By exploiting QTmax and QTend in combination with ST segment elevation, changes in ST segment elevation caused by hypo/hyperglycemia can be properly distinguished from changes caused by ischemia.
    Type: Grant
    Filed: January 27, 2009
    Date of Patent: May 15, 2012
    Assignee: Pacesetter, Inc.
    Inventors: Jong Gill, Peter Boileau, Rupinder Bharmi, Xiaoyi Min, Joseph J. Florio, Michael E. Benser, Gene A. Bornzin
  • Patent number: 8180439
    Abstract: An implanted cardiac rhythm management device is disclosed that is operative to detect myocardial ischemia. This is done by evaluating electrogram features to detect an electrocardiographic change; specifically, changes in electrogram segment during the early part of an ST segment. The early part of the ST segment is chosen to avoid the T-wave.
    Type: Grant
    Filed: July 29, 2010
    Date of Patent: May 15, 2012
    Assignee: Pacesetter, Inc.
    Inventors: Jong Gill, Peter Boileau, Gene A. Bornzin, Joseph J. Florio, Mohssen Fard
  • Patent number: 8162842
    Abstract: Methods and systems are presented for using an ICD to detect myocardial ischemia. One such method includes sensing via an implantable cardiac-rhythm-management device (ICRMD) a signal indicative of cardiac pressure; determining via a processor associated with the ICRMD, a derivative signal that is a first derivative of the sensed signal; measuring via the processor, a maximum positive value of the derivative signal; measuring via the processor, a maximum negative value of the derivative signal; and indicating via the processor, an ischemia based on a comparison of a ratio of the maximum positive value to the maximum negative value with a predetermined value.
    Type: Grant
    Filed: December 7, 2009
    Date of Patent: April 24, 2012
    Assignee: Pacesetter, Inc.
    Inventors: Jong Gill, Peter Boileau, Gene A. Bornzin, Joseph J. Florio, Xiaoyi Min
  • Patent number: 8090435
    Abstract: Techniques are described for detecting ischemia, hypoglycemia or hyperglycemia based on intracardiac electrogram (IEGM) signals. Ischemia is detected based on a shortening of the interval between the QRS complex and the end of a T-wave (QTmax), alone or in combination with a change in ST segment elevation. Alternatively, ischemia is detected based on a change in ST segment elevation combined with minimal change in the interval between the QRS complex and the end of the T-wave (QTend). Hypoglycemia is detected based on a change in ST segment elevation along with a lengthening of either QTmax or QTend. Hyperglycemia is detected based on a change in ST segment elevation along with minimal change in QTmax and in QTend. By exploiting QTmax and QTend in combination with ST segment elevation, changes in ST segment elevation caused by hypo/hyperglycemia can be properly distinguished from changes caused by ischemia.
    Type: Grant
    Filed: January 27, 2009
    Date of Patent: January 3, 2012
    Assignee: Pacesetter, Inc.
    Inventors: Jong Gill, Peter Boileau, Rupinder Bharmi, Xiaoyi Min, Joseph J. Florio, Michael E. Benser, Gene A. Bornzin
  • Publication number: 20110004111
    Abstract: An implanted cardiac rhythm management device is disclosed that is operative to detect myocardial ischemia. This is done by evaluating electrogram features to detect an electrocardiographic change; specifically, changes in electrogram segment during the early part of an ST segment. The early part of the ST segment is chosen to avoid the T-wave.
    Type: Application
    Filed: July 29, 2010
    Publication date: January 6, 2011
    Applicant: PACESETTER, INC.
    Inventors: Jong Gill, Peter Boileau, Gene A. Bornzin, Joseph J. Florio, Mohssen Fard
  • Patent number: 7792572
    Abstract: An implanted cardiac rhythm management device is disclosed that is operative to detect myocardial ischemia. This is done by evaluating electrogram features to detect an electrocardiographic change; specifically, changes in electrogram segment during the early part of an ST segment. The early part of the ST segment is chosen to avoid the T-wave.
    Type: Grant
    Filed: May 16, 2005
    Date of Patent: September 7, 2010
    Assignee: Pacesetter, Inc.
    Inventors: Jong Gill, Peter Boileau, Gene A. Bornzin, Joseph J. Florio, Mohssen Fard
  • Publication number: 20100094371
    Abstract: A coupled/paired stimulus pulse is delivered to the heart at an inter-pulse interval following one of i) detection of an intrinsic depolarization or ii) delivery of a primary stimulus pulse. Capture resulting from the coupled/paired stimulus pulse is sensed for. In response to capture by a coupled/paired stimulus pulse, the inter-pulse interval is incrementally decreased by a first amount until there is no capture by a coupled/paired stimulus pulse. In response to no capture by a coupled/paired stimulus pulse, the inter-pulse interval is incrementally increased by a second amount greater than the first amount, until capture by a coupled/paired stimulus pulse is detected. Once capture is again detected, paired/coupled pacing is delivered at the inter-pulse interval which resulted in capture for a predetermined period of time or until loss of capture occurs.
    Type: Application
    Filed: December 10, 2009
    Publication date: April 15, 2010
    Inventors: Gene A. Bornzin, Joseph J. Florio
  • Publication number: 20100081952
    Abstract: Methods and systems are presented for using an ICD to detect myocardial ischemia. One such method includes sensing via an implantable cardiac-rhythm-management device (ICRMD) a signal indicative of cardiac pressure; determining via a processor associated with the ICRMD, a derivative signal that is a first derivative of the sensed signal; measuring via the processor, a maximum positive value of the derivative signal; measuring via the processor, a maximum negative value of the derivative signal; and indicating via the processor, an ischemia based on a comparison of a ratio of the maximum positive value to the maximum negative value with a predetermined value.
    Type: Application
    Filed: December 7, 2009
    Publication date: April 1, 2010
    Applicant: PACESETTER, INC.
    Inventors: Jong Gill, Peter Boileau, Gene A. Bornzin, Joseph J. Florio, Xiaoyi Min
  • Patent number: 7648464
    Abstract: Methods and systems are presented for using an ICD to detect myocardial ischemia. In one embodiment, a method includes sensing a signal indicative of cardiac pressure, measuring a height of the sensed signal at a peak amplitude of the sensed signal, and measuring a duration of the sensed signal. The method further includes indicating an ischemia based on a comparison of a ratio of the height to the duration with a predetermined value. In another embodiment, a method includes sensing a signal indicative of cardiac pressure, determining a derivative signal that is a first derivative of the sensed signal, measuring a maximum positive value of the derivative signal, and measuring a maximum negative value of the derivative signal. The method further includes indicating an ischemia based on a comparison of a ratio of the maximum positive value to the maximum negative value with a predetermined value.
    Type: Grant
    Filed: July 19, 2006
    Date of Patent: January 19, 2010
    Assignee: Pacesetter, Inc.
    Inventors: Jong Gill, Peter Boileau, Gene A. Bornzin, Joseph J. Florio, Xiaoyi Min
  • Publication number: 20090177105
    Abstract: Techniques are described for detecting ischemia, hypoglycemia or hyperglycemia based on intracardiac electrogram (IEGM) signals. Ischemia is detected based on a shortening of the interval between the QRS complex and the end of a T-wave (QTmax), alone or in combination with a change in ST segment elevation. Alternatively, ischemia is detected based on a change in ST segment elevation combined with minimal change in the interval between the QRS complex and the end of the T-wave (QTend). Hypoglycemia is detected based on a change in ST segment elevation along with a lengthening of either QTmax or QTend. Hyperglycemia is detected based on a change in ST segment elevation along with minimal change in QTmax and in QTend. By exploiting QTmax and QTend in combination with ST segment elevation, changes in ST segment elevation caused by hypo/hyperglycemia can be properly distinguished from changes caused by ischemia.
    Type: Application
    Filed: January 27, 2009
    Publication date: July 9, 2009
    Applicant: PACESETTER, INC.
    Inventors: Jong Gill, Peter Boileau, Rupinder Bharmi, Xiaoyi Min, Joseph J. Florio, Michael E. Benser, Gene A. Bornzin
  • Publication number: 20090177104
    Abstract: Techniques are described for detecting ischemia, hypoglycemia or hyperglycemia based on intracardiac electrogram (IEGM) signals. Ischemia is detected based on a shortening of the interval between the QRS complex and the end of a T-wave (QTmax), alone or in combination with a change in ST segment elevation. Alternatively, ischemia is detected based on a change in ST segment elevation combined with minimal change in the interval between the QRS complex and the end of the T-wave (QTend). Hypoglycemia is detected based on a change in ST segment elevation along with a lengthening of either QTmax or QTend. Hyperglycemia is detected based on a change in ST segment elevation along with minimal change in QTmax and in QTend. By exploiting QTmax and QTend in combination with ST segment elevation, changes in ST segment elevation caused by hypo/hyperglycemia can be properly distinguished from changes caused by ischemia.
    Type: Application
    Filed: January 27, 2009
    Publication date: July 9, 2009
    Applicant: PACESETTER, INC.
    Inventors: Jong Gill, Peter Boileau, Rupinder Bharmi, Xiaoyi Min, Joseph J. Florio, Michael E. Benser, Gene A. Bornzin
  • Patent number: 7502644
    Abstract: Techniques are described for detecting ischemia, hypoglycemia or hyperglycemia based on intracardiac electrogram (IEGM) signals. Ischemia is detected based on a shortening of the interval between the QRS complex and the end of a T-wave (QTmax), alone or in combination with a change in ST segment elevation. Alternatively, ischemia is detected based on a change in ST segment elevation combined with minimal change in the interval between the QRS complex and the end of the T-wave (QTend). Hypoglycemia is detected based on a change in ST segment elevation along with a lengthening of either QTmax or QTend. Hyperglycemia is detected based on a change in ST segment elevation along with minimal change in QTmax and in QTend. By exploiting QTmax and QTend in combination with ST segment elevation, changes in ST segment elevation caused by hypo/hyperglycemia can be properly distinguished from changes caused by ischemia.
    Type: Grant
    Filed: January 25, 2005
    Date of Patent: March 10, 2009
    Assignee: Pacesetter, Inc.
    Inventors: Jong Gill, Peter Boileau, Rupinder Bharmi, Xiaoyi Min, Joseph J. Florio, Michael Benser, Gene A. Bornzin
  • Publication number: 20090018595
    Abstract: Techniques are described for detecting tachyarrhythmia and also for preventing T-wave oversensing using a narrowband bradycardia filter in combination with a narrowband tachycardia filter. In some embodiments, a separate wideband filter is also exploited. In one illustrative example, ventricular tachycardia (VT) is detected by: detecting a preliminary indication of VT using signals filtered by the bradycardia filter and, in response, confirming the detection of VT using signals filtered by the tachycardia filter. That is, the bradycardia filter, traditionally used only to detect bradycardia, is additionally used to provide a preliminary indication of VT. The tachycardia filter is then activated to confirm the detection of VT before therapy is delivered. In this manner, the tachycardia filter need not run continuously, but is instead activated only when there is some indication of possible VT, and hence power is saved.
    Type: Application
    Filed: July 11, 2007
    Publication date: January 15, 2009
    Applicant: PACESETTER, INC.
    Inventors: Rupinder Bharmi, Jeffery D. Snell, Gene A. Bornzin, Joseph J. Florio, Peter Boileau