Patents by Inventor Joseph J. Holbrook

Joseph J. Holbrook has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant modified thermostable NAD-dependent dehydrogenases and process for their production
    Patent number: 5354676
    Abstract: A recombinant thermophilic NAD-dependent dehydrogenase having a hydrophobic amino acid at position 104 and/or 102. The enzymes are effective in catalysing the dehydrogenation of homologues of pyruvic acid of formula CnH.sub.2n+1 COCOOH, wherein n is>1, to homologues of lactic acid of formula CH.sub.n H.sub.2n+1 CHOHCOOH, wherein n is>1.
    Type: Grant
    Filed: October 24, 1991
    Date of Patent: October 11, 1994
    Assignees: The University of Bristol, Public Health Laboratory Service Board
    Inventors: William N. Chia, Anthony R. Clarke, Joseph J. Holbrook, Helen M. Wilks, Anthony Atkinson