Patents by Inventor Joseph J. Kenny

Joseph J. Kenny has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 12 human secreted proteins
    Patent number: 8372948
    Abstract: The present invention relates to 12 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Grant
    Filed: November 3, 2008
    Date of Patent: February 12, 2013
    Assignee: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Paul E. Young, Joseph J. Kenny, Henrik S. Olsen, Paul A. Moore, Ying-Fei Wei, John M. Greene, Steven M. Ruben, Ding Liu, Paul R. Crocker
  • 12 Human Secreted Proteins
    Publication number: 20090311256
    Abstract: The present invention relates to 12 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: November 3, 2008
    Publication date: December 17, 2009
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Paul E. Young, Joseph J. Kenny, Henrik S. Olsen, Paul A. Moore, Ying-Fei Wei, John M. Greene, Steven M. Ruben, Ding Liu, Paul R. Crocker
  • I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1 and CD-95 induced apoptosis
    Patent number: 7056516
    Abstract: The present invention relates to a novel I-FLICE-1 or I-FLICE-2 protein which is a novel inhibitor of TNFR-1 and CD-95 induced apoptosis. In particular, isolated nucleic acid molecules are provided encoding the human I-FLICE-1 or I-FLICE-2 protein. I-FLICE-1 or I-FLICE-2 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of I-FLICE-1 or I-FLICE-2 activity. Also provided are therapeutic methods for treating diseases and disorders associated with apoptosis.
    Type: Grant
    Filed: November 17, 2003
    Date of Patent: June 6, 2006
    Assignees: Human Genome Sciences, Inc., The Regents of the University
    Inventors: Jian Ni, Craig A. Rosen, Vishva M. Dixit, Reiner L. Gentz, Joseph J. Kenny
  • Interleukin-19 antibodies
    Patent number: 7056681
    Abstract: The present invention concerns a novel human cytokine. In particular, isolated nucleic acid molecules are provided encoding interleukin-19 (IL-19). IL-19 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The IL-19 polypeptides of the present invention can also be used to raise polyclonal and monoclonal antibodies. The invention further concerns therapeutic methods for modulating cytokine production.
    Type: Grant
    Filed: April 30, 2003
    Date of Patent: June 6, 2006
    Assignee: Human Genome Sciences, Inc.
    Inventors: Craig A Rosen, Joseph J Kenny
  • I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1 and CD 95 induced apoptosis
    Publication number: 20040121387
    Abstract: The present invention relates to a novel I-FLICE-1 or I-FLICE-2 protein which is a novel inhibitor of TNFR-1 and CD-95 induced apoptosis. In particular, isolated nucleic acid molecules are provided encoding the human I-FLICE-1 or I-FLICE-2 protein. I-FLICE-1 or I-FLICE-2 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of I-FLICE-1 or I-FLICE-2 activity. Also provided are therapeutic methods for treating diseases and disorders associated with apoptosis.
    Type: Application
    Filed: November 17, 2003
    Publication date: June 24, 2004
    Applicants: Human Genome Sciences, Inc., The Regents of the University of Michigan
    Inventors: Jian Ni, Craig A. Rosen, Vishva M. Dixit, Reiner L. Gentz, Joseph J. Kenny
  • I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1 and CD-95 induced apoptosis
    Patent number: 6680171
    Abstract: The present invention relates to a novel I-FLICE-1 or I-FLICE-2 protein which is a novel inhibitor of INFR-1 and CD-95 induced apoptosis. In particular, isolated nucleic acid molecules are provided encoding the human I-FLICE-1 or I-FLICE-2 protein. I-FLICE-1 or I-FLICE-2 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of I-FLICE-1 or I-FLICE-2 activity. Also provided are therapeutic methods for treating diseases and disorders associated with apoptosis.
    Type: Grant
    Filed: January 21, 2000
    Date of Patent: January 20, 2004
    Assignees: Human Genome Sciences, Inc., The Regents of the University of Michigan
    Inventors: Jian Ni, Craig A. Rosen, Vishva M. Dixit, Reiner L. Gentz, Joseph J. Kenny
  • Interleukin-19
    Publication number: 20030181664
    Abstract: The present invention concerns a novel human cytokine. In particular, isolated nucleic acid molecules are provided encoding interleukin-19 (IL-19). IL-19 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention further concerns therapeutic methods for modulating cytokine production.
    Type: Application
    Filed: April 30, 2003
    Publication date: September 25, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Craig A. Rosen, Joseph J. Kenny
  • I-flice, a novel inhibitor of tumor necrosis factor receptor-1 and CD-95 induced apoptosis
    Patent number: 6623938
    Abstract: The present invention relates to a novel I-FLICE-1 or I-FLICE-2 protein which is a novel inhibitor of TNFR-1 and CD-95 induced apoptosis. In particular, isolated nucleic acid molecules are provided encoding the human I-FLICE-1 or I-FLICE-2 protein. I-FLICE-1 or I-FLICE-2 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of I-FLICE-1 or I-FLICE-2 activity. Also provided are therapeutic methods for treating diseases and disorders associated with apoptosis.
    Type: Grant
    Filed: January 21, 1998
    Date of Patent: September 23, 2003
    Assignees: Human Genome Sciences, Inc., The Regents of the University of Michigan
    Inventors: Jian Ni, Craig A. Rosen, Vishva M. Dixit, Reiner L. Gentz, Joseph J. Kenny
  • 12 human secreted proteins
    Publication number: 20030129685
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: April 18, 2001
    Publication date: July 10, 2003
    Inventors: Jian Ni, Paul E. Young, Joseph J. Kenny, Henrik S. Olsen, Paul A. Moore, Ying-Fei Wei, John M. Greene, Steven M. Ruben
  • Interleukin-19
    Patent number: 6583270
    Abstract: The present invention concerns a novel human cytokine. In particular, isolated nucleic acid molecules are provided encoding interleukin-19 (IL-19). IL-19 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention further concerns therapeutic methods for modulating cytokine production.
    Type: Grant
    Filed: August 31, 1999
    Date of Patent: June 24, 2003
    Assignee: Human Genome Sciences, Inc.
    Inventors: Craig A. Rosen, Joseph J. Kenny
  • 12 human secreted proteins
    Publication number: 20030055231
    Abstract: The present invention relates to 12 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: October 29, 2001
    Publication date: March 20, 2003
    Inventors: Jian Ni, Paul E. Young, Joseph J. Kenny, Henrik S. Olsen, Paul A. Moore, Ying-Fei Wei, John M. Greene, Steven M. Ruben, Ding Liu, Paul R. Crocker
  • Immune system-related polynucleotides, polypeptides, and antibodies
    Publication number: 20020164692
    Abstract: The present invention relates to novel human immune system-related polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human immune system-related polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human immune system-related polypeptides.
    Type: Application
    Filed: September 12, 2001
    Publication date: November 7, 2002
    Inventors: Jian Ni, David Hilbert, Joseph J. Kenny, Paul A. Moore, Gil H. Choi, Daniel R. Soppet, Reinhard Ebner, Joachim R. Gruber, Gregory A. Endress, Steven M. Ruben
  • Polynucleotides encoding interleukin-19
    Patent number: 5985614
    Abstract: The present invention concerns a novel human cytokine. In particular, isolated nucleic acid molecules are provided encoding interleukin-19 (IL-19). IL-19 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention further concerns therapeutic methods for modulating cytokine production.
    Type: Grant
    Filed: August 29, 1997
    Date of Patent: November 16, 1999
    Assignee: Human Genome Sciences, Inc.
    Inventors: Craig A. Rosen, Joseph J. Kenny